Dehydroepiandrosterone Modulates Nuclear Factor-κB Activation in Hippocampus of Diabetic Rats

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

[13] Catalase in vitro

1984 • 22,648 citations

[12] Assays of glutathione peroxidase

1984 • 4,695 citations

NF-κB Controls Expression of Inhibitor IκBα: Evidence for an Inducible Autoregulatory Pathway

1993 • 1,141 citations

Recent advances torwards understanding redox mechanisms in the activation of nuclear factor κb

2000 • 674 citations

NF-κB is activated and promotes cell death in focal cerebral ischemia

1999 • 648 citations

Mutual regulation of the transcriptional activator NF-kappa B and its inhibitor, I kappa B-alpha.

1993 • 639 citations

A COLORIMETRIC MICRO-METHOD FOR THE DETERMINATION OF GLUTATHIONE

1965 • 625 citations

Activation of NF-?B protects hippocampal neurons against oxidative stress-induced apoptosis: Evidence for induction of manganese superoxide dismutase and suppression of peroxynitrite production and protein tyrosine nitration

1997 • 572 citations

The NF-κB signal transduction pathway in aortic endothelial cells is primed for activation in regions predisposed to atherosclerotic lesion formation

2000 • 545 citations

The missing link: A single unifying mechanism for diabetic complications

2000 • 517 citations

The roles of hydrogen peroxide and superoxide as messengers in the activation of transcription factor NF-κB

1995 • 460 citations

Dehydroepiandrosterone (DHEA) and DHEA-sulfate (DHEAS) protect hippocampal neurons against excitatory amino acid-induced neurotoxicity

1998 • 444 citations

The Roles of Oxidative Stress and Antioxidant Treatment in Experimental Diabetic Neuropathy

1997 • 436 citations

Hyperglycemia-induced activation of nuclear transcription factor kappaB in vascular smooth muscle cells.

1999 • 320 citations

High Glucose Induces Antioxidant Enzymes in Human Endothelial Cells in Culture: Evidence Linking Hyperglycemia and Oxidative Stress

1996 • 312 citations

Molecular Mechanisms of Tumor Necrosis Factor α Gene Expression in Monocytic Cells via Hyperglycemia-induced Oxidant Stress-dependent and -independent Pathways

2000 • 308 citations

Activation of the Nuclear Factor-κB Is a Key Event in Brain Tolerance

2001 • 275 citations

Dehydroepiandrosterone (DHEA) protects hippocampal cells from oxidative stress-induced damage

1999 • 262 citations

Crucial Role of the Amino-Terminal Tyrosine Residue 42 and the Carboxyl-Terminal PEST Domain of IκBα in NF-κB Activation by an Oxidative Stress

2000 • 251 citations

Lack of the p50 subunit of nuclear factor-kappaB increases the vulnerability of hippocampal neurons to excitotoxic injury.

1999 • 241 citations

Transcription Factor Nuclear Factor-Kappa B is Activated in Neurons after Focal Cerebral Ischemia

2000 • 196 citations

Peripheral blood mononuclear cells isolated from patients with diabetic nephropathy show increased activation of the oxidative-stress sensitive transcription factor NF-kB

1999 • 190 citations

Vitamin E Decreases the Occurrence of Malformations in the Offspring of Diabetic Rats

1997 • 188 citations

Anti-oxidant treatment prevents the development of peripheral nerve dysfunction in streptozotocin-diabetic rats

1993 • 185 citations

Expression of influenza virus hemagglutinin activates transcription factor NF-kappa B

1995 • 181 citations

The association of hyperglycemia with cerebral edema in stroke.

1986 • 175 citations

Neuronal Actions of Dehydroepiandrosterone Possible Roles in Brain Development, Aging, Memory, and Affect

1995 • 172 citations

Activation of AP‐1 and Nuclear Factor‐κB Transcription Factors Is Involved in Hydrogen Peroxide‐Induced Apoptotic Cell Death of Olligodendrocytes

1999 • 171 citations

Possible involvement of the lipid-peroxidation product 4-hydroxynonenal in the formation of fluorescent chromolipids

1986 • 166 citations

Nuclear Factor-κB Regulates Induction of Apoptosis and Inhibitor of Apoptosis Protein-1 Expression in Vascular Smooth Muscle Cells

1999 • 165 citations

Dehydroepiandrosterone administration prevents the oxidative damage induced by acute hyperglycemia in rats

1997 • 143 citations

Hemorrhage Activates Myocardial NFκB and Increases TNF-α in the Heart

1997 • 136 citations

Dehydroepiandrosterone prevents oxidative injury induced by transient ischemia/reperfusion in the brain of diabetic rats.

2000 • 121 citations

Activation of NF-κB by Reactive Oxygen Intermediates in the Nervous System

1999 • 106 citations

Oxidative derangement in rat synaptosomes induced by hyperglycaemia: restorative effect of dehydroepiandrosterone treatment

2000 • 85 citations

Protective Effect of Dehydroepiandrosterone Against Copper-Induced Lipid Peroxidation in the Rat

1997 • 77 citations

Dehydroepiandrosterone selectively inhibits production of tumor necrosis factor α and Interlukin‐6 in astrocytes

1999 • 64 citations

Short-Term Effects of Dehydroepiandrosterone Treatment in Rats on Mitochondrial Respiration

1991 • 53 citations

Dehydroepiandrosterone protects bovine retinal capillary pericytes against glucose toxicity

1998 • 49 citations

Pathways of dehydroepiandrosterone formation in rat brain glia

2000 • 43 citations

Dehydroepiandrosterone pretreatment protects rats against the pro-oxidant and necrogenic effects of carbon tetrachloride

1993 • 37 citations

Influence of dehydroepiandrosterone on platelet aggregation, superoxide dismutase activity and serum lipid peroxide concentrations in rabbits with induced hypercholesterolemia.

2001 • 27 citations

THE BIOSYNTHESIS OF POLYSACCHARIDES. INCORPORATION OF <scp>d</scp>-(1-14C)GLUCOSE AND <scp>d</scp>-(6-14C)GLUCOSE INTO PLUM-LEAF POLYSACCHARIDES

1965 • 27 citations

Kinetic Mechanisms of IκB-related Kinases (IKK) Inducible IKK and TBK-1 Differ from IKK-1/IKK-2 Heterodimer

2002 • 26 citations

Breast duct fluid dehydroepiandrosterone sulphate in fibrocystic disease

1987 • 23 citations

Identification of an NADH plus iron dependent, Ca2+ activated hydrogen peroxide production in synaptosomes

1993 • 21 citations

Hemolytic effects of dehydroepiandrosterone in vitro

1997 • 10 citations

10 Linear Regression Models for Medical Data

2007 • 7 citations