Frequent Loss of Heterozygosity on Chromosome Arm 18q in Squamous Cell Carcinomas: Identification of 2 Regions of Loss--18q11.1-q12.3 and 18q21.1-q23

DPC4 , A Candidate Tumor Suppressor Gene at Human Chromosome 18q21.1

1996 • 2,320 citations

The 1993–94 Généthon human genetic linkage map

1994 • 1,870 citations

Identification of a Chromosome 18q Gene that Is Altered in Colorectal Cancers

1990 • 1,747 citations

MADR2 Maps to 18q21 and Encodes a TGFβ–Regulated MAD–Related Protein That Is Functionally Mutated in Colorectal Carcinoma

1996 • 855 citations

Allelic Loss of Chromosome 18q and Prognosis in Colorectal Cancer

1994 • 708 citations

DPC4 gene in various tumor types.

1996 • 680 citations

Allelotype of head and neck squamous cell carcinoma.

1994 • 349 citations

Recurrent cytogenetic abnormalities in squamous cell carcinomas of the head and neck region

1994 • 210 citations

An allelotype of squamous carcinoma of the head and neck using microsatellite markers.

1994 • 195 citations

DPC4, a candidate tumor suppressor gene, is altered infrequently in head and neck squamous cell carcinoma.

1996 • 164 citations

Sequential loss of heterozygosity at microsatellite motifs in preinvasive and invasive head and neck squamous carcinoma.

1995 • 160 citations

A Microsatellite Genetic Linkage Map of Human Chromosome 18

1993 • 153 citations

Allelic Loss at Chromosomes 3p, 8p, 13q, and l7p Associated With Poor Prognosis in Head and Neck Cancer

1994 • 126 citations

The DCC gene suppresses the malignant phenotype of transformed human epithelial cells.

1995 • 88 citations

Consistent Chromosome Abnormalities in Squamous Cell Carcinoma of the Vulva

1991 • 78 citations

Frequent loss of heterozygosity on chromosome 18 in ovarian adenocarcinoma which does not always include the DCC locus.

1992 • 78 citations

Evidence that loss of chromosome 18q is associated with tumor progression.

1997 • 68 citations

Nonrandom chromosome aberrations and clonal populations in head and neck cancer.

1993 • 49 citations

Alteration of the DCC tumor-suppressor gene in tumorigenic HPV-18 immortalized human keratinocytes transformed by nitrosomethylurea.

1993 • 47 citations

Chromosome 18: a possible site for a tumour suppressor gene deletion in squamous cell carcinoma of the head and neck

1995 • 29 citations

Loss of 18q and homozygosity for the DCC locus: possible markers for clinically aggressive squamous cell carcinoma.

1996 • 27 citations