Prostaglandin E2 releases luteinizing hormone-releasing hormone from the female juvenile hypothalamus through a Ca2+-dependent, calmodulin-independent mechanism

Calmodulin Plays a Pivotal Role in Cellular Regulation

1980 • 2,441 citations

Radioimmunoassay for Cyclic Nucleotides

1972 • 2,057 citations

Calmodulin—an intracellular calcium receptor

1980 • 964 citations

Radioimmunoassay of cyclic AMP and cyclic GMP.

1979 • 553 citations

Identification of a calcium-binding protein as a calcium-dependent regulator of brain adenylate cyclase.

1975 • 546 citations

Inhibitory action of chlorpromazine, dibucaine, and other phospholipid-interacting drugs on calcium-activated, phospholipid-dependent protein kinase.

1980 • 464 citations

STUDIES ON THE MECHANISM OF ACTION OF A NEW Ca²⁺ ANTAGONIST, 8‐(N,N‐DIETHYLAMINO)OCTYL 3,4,5‐TRIMETHOXYBENZOATE HYDROCHLORIDE IN SMOOTH AND SKELETAL MUSCLES

1975 • 347 citations

PHARMACOLOGICAL REGULATION OF CALMODULIN*

1980 • 341 citations

Catecholaminergic Modulation of Luteinizing Hormone-Releasing Hormone Release by Median Eminence Terminalsin Vitro*

1979 • 270 citations

R 24571: A new powerful inhibitor of red blood cell Ca++-transport ATPase and of calmodulin-regulated functions

1981 • 260 citations

Phosphorylation of the calcium antagonist receptor of the voltage-sensitive calcium channel by cAMP-dependent protein kinase.

1985 • 253 citations

Phospholipid-sensitive calcium-dependent protein kinase: Inhibition by antipsychotic drugs

1981 • 243 citations

Calcium Release from Skeletal Muscle Sarcoplasmic Reticulum: Site of Action of Dantrolene Sodium?

1976 • 242 citations

R 24 571: A potent inhibitor of calmodulin-activated enzymes

1981 • 241 citations

Pharmacological evaluation of a new Ca2+ antagonist, 8-(N,N-diethylamino)-octyl-3,4,5-trimethoxybenzoate hydrochloride (TMB-8): Studies in smooth muscles

1974 • 217 citations

The cytoplasmic concentration of free calcium in platelets is controlled by stimulators of cyclic AMP production (PGD2, PGE1, forskolin)

1983 • 217 citations

Specificity of the binding of trifluoperazine to the calcium-dependent activator of phosphodiesterase and to a series of other calcium-binding proteins

1978 • 207 citations

In Vivo Release of Luteinizing Hormone-Releasing Hormone Estimated with Push-Pull Cannulae from the Mediobasal Hypothalami of Ovariectomized, Steroid- Primed Rats*

1980 • 203 citations

Calmodulin in neurotransmitter release and synaptic function.

1982 • 172 citations

Phorbol myristate acetate-induced release of granule enzymes from human neutrophils: Inhibition by the calcium antagonist, 8-(N,N-diethylamino)-octyl 3,4,5-trimethoxybenzoate hydrochloride

1979 • 169 citations

Hormone secretagogues increase cytosolic calcium by increasing cAMP in corticotropin-secreting cells.

1985 • 169 citations

Release of Prostaglandin Es by Hypothalamic Tissue:Evidence for Their Involvement in Catecholamine-Induced Luteinizing Hormone-Releasing Hormone Release*

1979 • 161 citations

Effect of dantrolene sodium on calcium movements in single muscle fibres

1974 • 133 citations

Calmodulin regulation of adenylate cyclase activity

1985 • 116 citations

Prostaglandin Involvement in Hypothalamic Control of Gonadotropin and Prolactin Release

1973 • 114 citations

Evidence for Involvement of α-Adrenergic Receptors in Norepinephrine-Induced Prostaglandin E_<and Luteinizing Hormone-Releasing Hormone Release from the Median Eminence*

1982 • 100 citations

Progesterone Action on the LHRH and the Nigrostriatal Dopamine Neuronal Systems: In Vitro and in Vivo Studies

1985 • 90 citations

Prostaglandin E₂-Induced Release of LHRH into Hypophysial Portal Blood¹

1975 • 90 citations

Calcium Entry Blockers and Tissue Protection

1985 • 84 citations

Development of Estradiol-Positive Feedback on Luteinizing Hormone Release in the Female Rat: A Quantitative Study*

1981 • 80 citations

Calcium as intracellular messenger: sensitivity modulation, C-kinase pathway, and sustained cellular response.

1984 • 79 citations

Trifluoperazine, a calmodulin inhibitor, blocks secretion in cultured chromaffin cells at a step distal from calcium entry

1982 • 76 citations

Estrogen Augmentation of Gonadotropin-Stimulated Progestin Biosynthesis in Cultured Rat Granulosa Cells*

1983 • 74 citations

Pharmacological Evaluation of a New Ca<sup>++</sup> Antagonist, 8-(N, N-Diethylamino)Octyl 3,4,5-Trimethoxybenzoate Hydrochloride (TMB-8): Studies in Skeletal Muscles

1974 • 69 citations

Blockade of hepatic α‐adrenergic receptors and responses by chlorpromazine and trifluoperazine

1981 • 68 citations

Effect of Inhibitors of Prostaglandin Synthesis on Gonadotropin Release in the Rat¹

1975 • 65 citations

Ca2+-dependent regulation of rat caudate nucleus adenylate cyclase and effects on the response to dopamine.

1981 • 63 citations

Responsiveness of Immature versus Adult Male Rat Hypothalami to Dibutyryl Cyclic AMP- and Forskolin-Induced LHRH Release in vitro

1985 • 56 citations

Noradrenaline and Prostaglandin E<sub>2</sub> Stimulate LH-RH Release from Rat Median Eminence through Distinct 1-Alpha-Adrenergic and PGE<sub>2</sub> Receptors

1984 • 56 citations

Prostaglandin E₂-Induced Luteinizing Hormone- Releasing Hormone Release Involves Mobilization of Intracellular Ca⁺²*

1985 • 54 citations

Activation of Estradiol-Positive Feedback at Puberty: Estradiol Sensitizes the LHRH-Releasing System at Two Different Biochemical Steps

1986 • 53 citations

An Increase in Hypothalamic Capacity to Synthesize Prostaglandin E₂Precedes the First Preovulatory Surge of Gonadotropins*

1982 • 52 citations

Activation of two different but complementary biochemical pathways stimulates release of hypothalamic luteinizing hormone-releasing hormone.

1986 • 52 citations

Ca2+ and calmodulin-regulated endogenous tubulin kinase activity in presynaptic nerve terminal preparations

1982 • 50 citations

Factors altering the secretion of LHRH from super-fused fragments of rat hypothalamus

1980 • 38 citations

Stimulation of Cyclic Adenosine 3′,5′-Monophosphate Production Enhances Hypothalamic Luteinizing Hormone-Releasing Hormone Release without Increasing Prostaglandin E₂Synthesis: Studies in Prepubertal Female Rats*

1985 • 38 citations

Identification of a novel calcium binding protein from bovine brain

1983 • 34 citations

Effects of prostaglandin E2, forskolin and cholera toxin on cAMP production and in vitro LH-RH release from the rat hypothalamus

1986 • 30 citations

Binding of dantrolene sodium to muscle intracellular membranes

1980 • 30 citations

Purification and characterization of a novel Ca2+-binding protein (CBP-18) from bovine brain.

1984 • 28 citations

Calcium Metabolism and Enzyme Secretion in Guinea Pig Pancreas

1978 • 26 citations

Release of E Prostaglandins into the Cerebrospinal Fluid and Its Inhibition by Melatonin after Cervical Stimulation in the Rabbit*

1982 • 25 citations

Postsynaptic inhibition of neuromuscular transmission by trifluoperazine.

1981 • 24 citations

Calmodulin Involvement on the Ca<sup>++</sup>-Dependent Release of LHRH and SRIF in vitro

1984 • 23 citations

Copper amplification of prostaglandin E2 stimulation of the release of luteinizing hormone-releasing hormone is a postreceptor event.

1987 • 15 citations

Evidence for the mobilization of cellular calcium by prostacyclin in cat adrenocortical cells: The effect of TMB-8

1980 • 15 citations

Effects of calcium antagonists and calmodulin inhibitors on angiotensin II-induced prostaglandin productions in the isolated dog renal arteries

1985 • 13 citations

Hazards of Chemical Carcinogens and Mutagens

1973 • 13 citations

Extra- and intracellular Ca2+ requirements for lysosomal enzyme secretion in human neutrophils

1982 • 9 citations

Dual effect of calmidazolium (R 24571) on transmitter release at the frog neuromuscular junction

1985 • 8 citations

Effects of 8-(N, N-Diethylamino)Octyl 3,4,5-Trimethoxybenzoate HCI (TMB-8) on Washed Blood Platelets with Special Reference to a Specific Loss of Serotonin

1982 • 6 citations