Prognostic value oferb-B2 andmyc amplification in breast cancer imprints

Regression Models and Life-Tables

1992 • 27,454 citations

Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/ neu Oncogene

1987 • 11,429 citations

Design and analysis of randomized clinical trials requiring prolonged observation of each patient. II. Analysis and examples

1977 • 8,468 citations

Quantitative analysis of MDR1 (multidrug resistance) gene expression in human tumors by polymerase chain reaction.

1990 • 736 citations

Overexpression of the EGF receptor-related proto-oncogene erbB-2 in human mammary tumor cell lines by different molecular mechanisms.

1987 • 619 citations

Ten year follow-up results of patients with carcinoma of the breast in a co-operative clinical trial evaluating surgical adjuvant chemotherapy.

1975 • 367 citations

Computing an Exact Confidence Interval for the Common Odds Ratio in Several 2×2 Contingency Tables

1985 • 337 citations

The structure of the human tissue-type plasminogen activator gene: correlation of intron and exon structures to functional and structural domains.

1984 • 303 citations

Identification and nucleotide sequence of a human locus homologous to the v-myc oncogene of avian myelocytomatosis virus MC29

1983 • 287 citations

Detection of amplified oncogenes by differential polymerase chain reaction.

1989 • 209 citations

Amplification of cellular oncogenes: A predictor of clinical outcome in human cancer

1990 • 203 citations

c-erbB-2 oncogene as a prognostic marker in breast cancer

1991 • 137 citations

Sequence, structure and promoter characterization of the human thymidine kinase gene

1987 • 129 citations

Computerized nuclear morphometry as an objective method for characterizing human cancer cell populations.

1978 • 108 citations

c‐myc amplification is an independent prognostic factor in postmenopausal breast cancer

1992 • 106 citations

Role of myc amplification and overexpression in cell growth, differentiation and death.

1993 • 90 citations

Human HER2 (neu) promoter: evidence for multiple mechanisms for transcriptional initiation.

1987 • 77 citations

Molecular Genetic Changes in Human Breast Cancer

1993 • 59 citations

Appearance and detection of multiple copies of the mdr‐1 gene in clinical samples of mammary carcinoma

1992 • 34 citations

Detection and temporal appearance of multiple copies of c-erb-B2 genes in advanced mammary carcinoma using fine needle biopsies and the polymerase chain reaction

1992 • 24 citations

The imprint method for the cytodiagnosis of lymphadenopathies and of tumors of the head and neck.

1971 • 19 citations

Breast cancer: prognostic significance of c-erb-B2 and int-2 amplification compared with DNA ploidy, S-phase fraction, and conventional clinicopathological features

1994 • 18 citations