Salutary consequences of blockade of platelet activating factor in hemorrhagic shock

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Is platelet activating factor (PAF) a mediator of endotoxin shock?

1985 • 247 citations

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The Ginkgolides: Potent platelet-activating factor antagonists isolated from Ginkgo biloba L.. Chemistry, pharmacology and clinical applications

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CV-6209, a highly potent antagonist of platelet activating factor in vitro and in vivo.

1987 • 128 citations

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1984 • 123 citations

Role of Platelet-Activating Factor-Acether in Mediating Guinea Pig Anaphylaxis

1986 • 101 citations

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1982 • 96 citations

Coronary vasoconstriction in the rat, isolated perfused heart induced by platelet‐activating factor is mediated by leukotriene C₄

1986 • 95 citations

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1983 • 86 citations

Role of platelet activating factor in propagation of cardiac damage during myocardial ischemia.

1988 • 85 citations

Release of leukotriene C4 by isolated, perfused rat small intestine in response to platelet-activating factor.

1986 • 82 citations

Platelet-Activating Factor: An Ether Lipid with Biological Activity

1983 • 61 citations

Platelet-activating factor increases lung vascular permeability to protein

1986 • 56 citations

Interaction between myocardial depressant factor and vasoactive mediators with ischemia and shock

1987 • 53 citations

Pathophysiology of Shock‐Induced Disturbances in Tissue Homeostasis

1985 • 29 citations

Detection by chemical methods of a myocardial depressant factor in plasma of animals in circulatory shock.

1973 • 27 citations

Platelet sequestration in lung with hemorrhagic shock and reinfusion in dogs

1981 • 27 citations

Inhibition of the platelet activating factor (PAF)-induced in vivo responses in rats by trans-2,5-(3,4,5-trimethoxyphenyl) tetrahydrofuran (L-652,731), a PAF receptor antagonist.

1986 • 24 citations

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A more appropriate statistical method for analyzing mortality data in shock research.

1985 • 21 citations

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1986 • 19 citations

Heterogeneity of Vascular Smooth Muscle Responsiveness to Lipid Vasoactive Mediators

1987 • 15 citations

Correlation of Spontaneous Microaggregate Formation with the Severity of Trauma in Man

1983 • 15 citations

Beneficial actions of antagonism of peptide leukotrienes in hemorrhagic shock.

1988 • 14 citations

Investigations into the aggregation of platelets in flowing blood during hemorrhagic shock.

1973 • 3 citations