Propionibacterium acnes induces acute TNFα-mediated apoptosis of hepatocytes followed by inflammatory T-cell-mediated granulomatous hepatitis in mice

An endotoxin-induced serum factor that causes necrosis of tumors.

1975 • 4,522 citations

Lethal effect of the anti-Fas antibody in mice

1993 • 1,915 citations

A novel domain within the 55 kd TNF receptor signals cell death

1993 • 1,302 citations

Induction of apoptosis in mature T cells by tumour necrosis factor

1995 • 1,139 citations

Two TNF receptors

1992 • 1,048 citations

A T cell-dependent experimental liver injury in mice inducible by concanavalin A.

1992 • 1,041 citations

The two different receptors for tumor necrosis factor mediate distinct cellular responses.

1991 • 815 citations

Involvement of the CD95 (APO-1/Fas) receptor and ligand in liver damage.

1995 • 706 citations

Ligand passing: the 75-kDa tumor necrosis factor (TNF) receptor recruits TNF for signaling by the 55-kDa TNF receptor.

1993 • 573 citations

Lethal toxicity of lipopolysaccharide and tumor necrosis factor in normal and D-galactosamine-treated mice.

1987 • 560 citations

T cell activation-associated hepatic injury: mediation by tumor necrosis factors and protection by interleukin 6.

1994 • 519 citations

Essential roles of the Fas ligand in the development of hepatitis

1997 • 483 citations

Modulation of Nitrogen Oxide Synthesis In Vivo: NG-Monomethyl-L-Arginine Inhibits Endotoxin-Induced Nitrate/Nitrate Biosynthesis While Promoting Hepatic Damage

1990 • 345 citations

Activation of the 55 kDa TNF receptor is necessary and sufficient for TNF-induced liver failure, hepatocyte apoptosis, and nitrite release.

1995 • 332 citations

Tumor necrosis factor is a terminal mediator in galactosamine/endotoxin-induced hepatitis in mice

1989 • 304 citations

ROLE OF MONONUCLEAR INFILTRATING CELLS IN PATHOGENESIS OF HEPATITIS

1978 • 185 citations

Critical involvement of interferon gamma in the pathogenesis of T-cell activation-associated hepatitis and regulatory mechanisms of interleukin-6 for the manifestations of hepatitis

1996 • 179 citations

Involvement of tumor necrosis factor-α in the pathogenesis of activated macrophage-mediated hepatitis in mice

1990 • 128 citations

Corynebacterium parvum as the Priming Agent in the Production of Tumor Necrosis Factor in the Mouse2

1977 • 124 citations

Preparation of specific antibodies against murine IL-1ra and the establishment of IL-1ra as an endogenous regulator of bacteria-induced fulminant hepatitis in mice

1995 • 82 citations

Tumor necrosis factor receptor p55 is essential for intrahepatic granuloma formation and hepatocellular apoptosis in a murine model of bacterium-induced fulminant hepatitis

1997 • 81 citations

Tumor necrosis factor-α regulatesin vivo nitric oxide synthesis and induces liver injury during endotoxemia

1994 • 80 citations

TNF receptors in the microvascular pathology of acute respiratory distress syndrome and cerebral malaria

1997 • 78 citations

Nitric Oxide Synthase Expression Is Induced in Hepatocytes in Vivo during Hepatic Inflammation

1993 • 68 citations

Parenchymal and nonparenchymal liver cells and their interaction in the local immune response.

1995 • 62 citations

Infiltrated cells in experimental allergic encephalomyelitis by additional intracerebral injection in myelin-basic-protein-sensitized B6 mice

1997 • 11 citations

A sequential study of hepatic structural damage following the intravenous injection of Corynebacterium parvum.

1986 • 1 citations