Nicotinic and muscarinic agonists, phorbol esters, and agents which raise cyclic AMP levels phosphorylate distinct groups of proteins in the superior cervical ganglion

High resolution two-dimensional electrophoresis of proteins.

1975 • 19,515 citations

Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

1982 • 4,786 citations

Inositol trisphosphate and diacylglycerol as second messengers

1984 • 3,535 citations

The role of protein phosphorylation in neural and hormonal control of cellular activity

1982 • 1,116 citations

Protein kinase C as a possible receptor protein of tumor-promoting phorbol esters.

1983 • 890 citations

Direct phosphorylation of brain tyrosine hydroxylase by cyclic AMP-dependent protein kinase: mechanism of enzyme activation.

1978 • 286 citations

Purification to homogeneity of protein kinase C from bovine brain-identity with the phorbol ester receptor.

1984 • 283 citations

Calcium/phospholipid regulates phosphorylation of a Mr "87k" substrate protein in brain synaptosomes.

1982 • 257 citations

Calcium/phospholipid-dependent protein kinase (protein kinase C) phosphorylates and activates tyrosine hydroxylase.

1984 • 219 citations

Tyrosine hydroxylase: a substrate of cyclic AMP-dependent protein kinase.

1980 • 189 citations

Phosphorylation and activation of tyrosine hydroxylase mediate the cAMP-induced increase in catecholamine biosynthesis in adrenal chromaffin cells.

1982 • 177 citations

Phosphorylation of tyrosine hydroxylase by calmodulin-dependent multiprotein kinase.

1984 • 152 citations

Tyrosine 3-monooxygenase is phosphorylated by Ca2+-, calmodulin-dependent protein kinase, followed by activation by activator protein

1981 • 138 citations

Phosphorylation and activation of tyrosine hydroxylase mediate the acetylcholine-induced increase in catecholamine biosynthesis in adrenal chromaffin cells.

1982 • 106 citations

Intracellular signals in the brain.

1979 • 103 citations

Experimental Approaches to Understanding the Role of Protein Phosphorylation in the Regulation of Neuronal Function

1983 • 92 citations

Nerve impulses increase the phosphorylation state of protein I in rabbit superior cervical ganglion

1982 • 85 citations

Dopamine and depolarizing agents regulate the state of phosphorylation of protein I in the mammalian superior cervical sympathetic ganglion.

1980 • 84 citations

Progress in Cholinergic Biology: Model Cholinergic Synapses

1983 • 73 citations

Distribution of protein I and regulation of its state of phosphorylation in the rabbit superior cervical ganglion

1982 • 57 citations

Regulation of Cyclic AMP Accumulation in a Rat Sympathetic Ganglion: Effects of Vasoactive Intestinal Polypeptide

1982 • 46 citations

Phospholipase A2 inhibitors block catecholamine secretion and calcium uptake in cultured bovine adrenal medullary cells.

1983 • 40 citations

Muscarinic cholinergic stimulation of phosphatidylinositol turnover in isolated rat superior cervical sympathetic ganglia

1976 • 38 citations

Phosphorylation of tyrosine hydroxylase in the superior cervical ganglion

1984 • 29 citations

Electrical stimulation increases phosphorylation of tyrosine hydroxylase in superior cervical ganglion of rat.

1984 • 26 citations

Muscarine increases tyrosine 3-monooxygenase activity and phospholipid metabolism in the superior cervical ganglion of the rat.

1984 • 26 citations