Chemical modification of enzymes: Critical evaluation of the graphical correlation between residual enzyme activity and number of groups modified

Chemical Modification of Proteins

2012 • 1,097 citations

Inactivation of Myosin by 2,4-Dinitrophenol and Protection by Adenosine Triphosphate and Other Phosphate Compounds

1963 • 409 citations

A Method for Characterizing the Type and Numbers of Groups Involved in Enzyme Action

1961 • 236 citations

Covalent Labeling of Active Sites

1967 • 225 citations

Identification of Amino Acids Involved in Phosphoglucomutase Action

1962 • 224 citations

Chemical modification of proteins: Selected methods and analytical procedures

1975 • 79 citations

Relation between modification of functional groups of proteins and their biological activity. I.A graphical method for the determination of the number and type of essential groups.

1962 • 64 citations

A reactive arginine in adenylate kinase

1975 • 62 citations

An essential residue at the active site of aspartate transcarbamylase.

1976 • 60 citations

The Number of Catalytically Essential Carboxyl Groups in Pepsin

1972 • 59 citations

Selective chemical modification of arginine residues in mitochondrial malate dehydrogenase

1974 • 54 citations

Identification of essential arginine residues in glucose-6-phosphate dehydrogenase from Leuconostoc mesenteroides.

1977 • 33 citations

Kinetics of irreversible enzyme inhibition: Co-operative effects

1977 • 29 citations

Kinetics of irreversible enzyme inhibition: The tsou plot in irreversible binding co-operativity

1978 • 23 citations

Inactivation and modification of lactate oxidase with fluorodinitrobenzene

1978 • 17 citations

Inactivation of Salmonella phosphoribosylpyrophosphate synthetase by specific chemical modification of a lysine residue

1978 • 11 citations