The Molecular Basis of Vitamin E Retention: Structure of Human α-Tocopherol Transfer Protein

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1998 • 15,791 citations

Refinement of Macromolecular Structures by the Maximum-Likelihood Method

1997 • 14,729 citations

Improved methods for building protein models in electron density maps and the location of errors in these models

1991 • 12,831 citations

LIGPLOT: a program to generate schematic diagrams of protein-ligand interactions

1995 • 5,246 citations

Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants

1993 • 3,564 citations

Automated MAD and MIR structure solution

1999 • 3,079 citations

Automated protein model building combined with iterative structure refinement.

1999 • 2,428 citations

Evaluation of single-crystal X-ray diffraction data from a position-sensitive detector

1988 • 1,516 citations

Atomic Structures of the Human Immunophilin FKBP-12 Complexes with FK506 and Rapamycin

1993 • 1,202 citations

A Micro Biuret Method for Protein Determination Determination of Total Protein in Cerebrospinal Fluid

1953 • 1,089 citations

Detection, delineation, measurement and display of cavities in macromolecular structures

1994 • 964 citations

Is vitamin E the only lipid-soluble, chain-breaking antioxidant in human blood plasma and erythrocyte membranes?

1983 • 800 citations

Affinity for α‐tocopherol transfer protein as a determinant of the biological activities of vitamin E analogs

1997 • 624 citations

Ataxia with isolated vitamin E deficiency is caused by mutations in the α–tocopherol transfer protein

1995 • 561 citations

An essential role for a phospholipid transfer protein in yeast Golgi function

1990 • 534 citations

Commission on Biochemical Nomenclature

1987 • 431 citations

Clinical features and classification of inherited ataxias.

1993 • 422 citations

Human plasma and tissue alpha-tocopherol concentrations in response to supplementation with deuterated natural and synthetic vitamin E

1998 • 382 citations

Ataxia with Isolated Vitamin E Deficiency: Heterogeneity of Mutations and Phenotypic Variability in a Large Number of Families

1998 • 302 citations

MOLECULAR MECHANISMS OF VITAMIN E TRANSPORT

1999 • 276 citations

Crystal structure of the Saccharomyces cerevisiae phosphatidylinositol- transfer protein

1998 • 261 citations

Biokinetics of and discrimination between dietaryRRR‐ andSRR‐α‐tocopherols in the male rat

1987 • 256 citations

Delayed-onset ataxia in mice lacking α-tocopherol transfer protein: Model for neuronal degeneration caused by chronic oxidative stress

2001 • 254 citations

Impaired ability of patients with familial isolated vitamin E deficiency to incorporate alpha-tocopherol into lipoproteins secreted by the liver.

1990 • 242 citations

RRR- and SRR-alpha-tocopherols are secreted without discrimination in human chylomicrons, but RRR-alpha-tocopherol is preferentially secreted in very low density lipoproteins.

1990 • 227 citations

Human α-tocopherol transfer protein: cDNA cloning, expression and chromosomal localization

1995 • 224 citations

Adult-Onset Spinocerebellar Dysfunction Caused by a Mutation in the Gene for the α-Tocopherol–Transfer Protein

1995 • 186 citations

α-Tocopherol Transfer Protein Is Important for the Normal Development of Placental Labyrinthine Trophoblasts in Mice

2001 • 179 citations

A Novel Human Tocopherol-associated Protein

2000 • 175 citations

Friedreich‐like ataxia with retinitis pigmentosa caused by the His¹⁰¹Gln mutation of the α‐Tocopherol transfer protein gene

1997 • 141 citations

Obligatory role of bile for the intestinal absorption of vitamin E

1970 • 141 citations

Stereoisomers of alpha-tocopheryl acetate. II. Biopotencies of all eight stereoisomers, individually or in mixtures, as determined by rat resorption-gestation tests.

1982 • 135 citations

Structure of a Multifunctional Protein

2001 • 131 citations

Yeast Sec14p Deficient in Phosphatidylinositol Transfer Activity Is Functional In Vivo

1999 • 130 citations

Supernatant protein factor, which stimulates the conversion of squalene to lanosterol, is a cytosolic squalene transfer protein and enhances cholesterol biosynthesis

2001 • 106 citations

Nascent VLDL from liver perfusions of cynomolgus monkeys are preferentially enriched in RRR- compared with SRR-alpha-tocopherol: studies using deuterated tocopherols.

1990 • 100 citations

Structure of apo-phosphatidylinositol transfer protein alpha provides insight into membrane association

2002 • 88 citations

Postmortem study of ataxia with retinitis pigmentosa by mutation of the alpha -tocopherol transfer protein gene

2000 • 88 citations

Biodiscrimination of the Eight α-Tocopherol Stereoisomers Results in Preferential Accumulation of the Four 2R Forms in Tissues and Plasma of Rats

1996 • 86 citations

Crystal Structure of the Human Supernatant Protein Factor

2002 • 66 citations

Nomenclature of Tocopherols and Related Compounds

1982 • 61 citations

Vitamin E in foods from high and low linoleic acid diets

1986 • 59 citations

Clinical comparison between AVED patients with 744 del A mutation and Friedreich ataxia with GAA expansion in 15 Moroccan families

2002 • 57 citations

Discrimination of solvent from protein regions in native Fouriers as a means of evaluating heavy-atom solutions in the MIR and MAD methods

1999 • 53 citations

Structural Factors Contributing to the Hydrophobic Effect: The Partly Exposed Hydrophobic Minicore in Chymotrypsin Inhibitor 2

1995 • 40 citations

Molecular cloning and structural analysis of the human gene encoding cellular retinaldehyde-binding protein.

1994 • 38 citations

[1] Shake-and-bake: An algorithm for automatic solution ab initio of crystal structures

1997 • 37 citations

Genomic characterization of human SEC14L1 splice variants within a 17q25 candidate tumor suppressor gene region and identification of an unrelated embedded expressed sequence tag

2001 • 21 citations

Expression and Refolding of Recombinant Human α-Tocopherol Transfer Protein Capable of Specific α-Tocopherol Binding

2002 • 20 citations

The structure of phosphatidylinositol transfer protein α reveals sites for phospholipid binding and membrane association with major implications for its function

2002 • 13 citations