INDUCTION OF ALLOGRAFT NONRESPONSIVENESS AFTER INTRATHYMIC INOCULATION WITH DONOR CLASS I ALLOPEPTIDES

CD28-B7 blockade after alloantigenic challenge in vivo inhibits Th1 cytokines but spares Th2.

1995 • 532 citations

CHRONIC REJECTION—AN UNDEFINED CONUNDRUM

1991 • 291 citations

Donor major histocompatibility complex (MHC) peptides are presented by recipient MHC molecules during graft rejection.

1992 • 266 citations

Rejection of skin allografts by indirect allorecognition of donor class I major histocompatibility complex peptides.

1992 • 218 citations

CD28-B7 costimulatory blockade by CTLA4Ig prevents actively induced experimental autoimmune encephalomyelitis and inhibits Th1 but spares Th2 cytokines in the central nervous system.

1995 • 204 citations

CAN GRAFT ENDOTHELIAL CELLS INITIATE A HOST ANTI-GRAFT IMMUNE RESPONSE?1

1996 • 163 citations

THYMIC RECOGNITION OF CLASS II MAJOR HISTOCOMPATIBILITY COMPLEX ALLOPEPTIDES INDUCES DONOR-SPECIFIC UNRESPONSIVENESS TO RENAL ALLOGRAFTS

1993 • 141 citations

MECHANISMS OF ACQUIRED THYMIC UNRESPONSIVENESS TO RENAL ALLOGRAFTS

1994 • 129 citations

PREVENTION OF TH1 RESPONSES IS CRITICAL FOR TOLERANCE1

1996 • 112 citations

MECHANISMS OF ALLO-RECOGNITION

1994 • 94 citations

MEDIATION OF ACUTE BUT NOT CHRONIC REJECTION OF MHC-INCOMPATIBLE RAT KIDNEY GRAFTS BY ALLOREACTIVE CD4 T CELLS ACTIVATED BY THE DIRECT PATHWAY OF SENSITIZATION

1993 • 89 citations

Processed MHC class I alloantigen as the stimulus for CD4+ T-cell dependent antibody-mediated graft rejection

1992 • 89 citations

MECHANISMS OF ALLO-RECOGNITION

1994 • 85 citations

T cell requirements for the rejection of renal allografts bearing an isolated class I MHC disparity.

1990 • 80 citations

The molecular immunology of acute rejection: an overview

1993 • 78 citations

INDIRECT T CELL ALLORECOGNITION OF DONOR ANTIGENS CONTRIBUTES TO THE REJECTION OF VASCULARIZED KIDNEY ALLOGRAFTS

1995 • 74 citations

INDUCTION OF SPECIFIC UNRESPONSIVENESS (TOLERANCE) TO SKIN ALLOGRAFTS BY INTRATHYMIC DONOR-SPECIFIC SPLENOCYTE INJECTION IN ANTILYMPHOCYTE SERUM-TREATED MICE

1992 • 72 citations

PEPTIDES DERIVED FROM α-HELICES OF ALLOGENEIC CLASS I MAJOR HISTOCOMPATIBILITY COMPLEX ANTIGENS ARE POTENT INDUCERS OF CD4+ AND CD8+ T CELL AND B CELL RESPONSES AFTER CARDIAC ALLOGRAFT REJECTION

1995 • 69 citations

Peptide-induced changes in class I heavy chains alter allorecognition.

1993 • 66 citations

Cell‐type‐specific recognition of allogeneic cells by alloreactive cytotoxic T cells: A consequence of peptide‐dependent allorecognition

1991 • 64 citations

EFFECTIVENESS OF INTRATHYMIC INOCULATION OF SOLUBLE ANTIGENS IN THE INDUCTION OF SPECIFIC UNRESPONSIVENESS TO RAT ISLET ALLOGRAFTS WITHOUT TRANSIENT RECIPIENT IMMUNOSUPPRESSION

1994 • 63 citations

Rapamycin inhibits production of cytotoxic but not noncytotoxic antibodies and preferentially activates T helper 2 cells that mediate long-term survival of heart allografts in rats.

1994 • 61 citations

ACQUIRED SYSTEMIC TOLERANCE TO RAT CARDIAC ALLOGRAFTS INDUCED BY INTRATHYMIC INOCULATION OF SYNTHETIC POLYMORPHIC MHC CLASS I ALLOPEPTIDES1,2

1996 • 52 citations

Cytokine and alloantibody networks in long term cardiac allografts in rat recipients treated with rapamycin.

1996 • 52 citations

EFFECTIVENESS OF INTRATHYMIC INOCULATION OF SOLUBLE ANTIGENS IN THE INDUCTION OF SPECIFIC UNRESPONSIVENESS TO RAT ISLET ALLOGRAFTS WITHOUT TRANSIENT RECIPIENT IMMUNOSUPPRESSION

1994 • 52 citations

PROMOTION OF RAT CARDIAC ALLOGRAFT SURVIVAL BY INTRATHYMIC INOCULATION OF DONOR SPLENOCYTES

1993 • 48 citations

INDUCTION OF ALLOGRAFT NONRESPONSIVENESS AFTER INTRATHYMIC INOCULATION WITH DONOR CLASS I ALLOPEPTIDES

1997 • 39 citations

Alloreactive 2C T cells recognize a self peptide in the context of the mutant Kbm3 molecule.

1995 • 38 citations

DOWNREGULATION OF INTRAGRAFT IFN-γ EXPRESSION CORRELATES WITH INCREASED IgG1 ALLOANTIBODY RESPONSE FOLLOWING INTRATHYMIC IMMUNOMODULATION OF SENSITIZED RAT RECIPIENTS1,2

1995 • 36 citations

PEPTIDES DERIVED FROM α-HELICES OF ALLOGENEIC CLASS I MAJOR HISTOCOMPATIBILITY COMPLEX ANTIGENS ARE POTENT INDUCERS OF CD4+ AND CD8+ T CELL AND B CELL RESPONSES AFTER CARDIAC ALLOGRAFT REJECTION

1995 • 32 citations

Specific T-cell tolerance may reflect selective activation of lymphokine synthesis.

1995 • 29 citations

GENETIC CONTROL OF THE HUMORAL IMMUNE RESPONSE TO XENOGRAFTS

1995 • 29 citations

Structure and diversity of rat T cell receptor alpha-chain genes.

1993 • 22 citations

THE ALLOANTIBODY NETWORK FOLLOWING INTRATHYMIC IMMUNOMODULATION OF SENSITIZED RAT RECIPIENTS OF CARDIAC ALLOGRAFTS1,2

1995 • 20 citations

TOLERANCE INDUCTION TO CARDIAC ALLOGRAFTS BY SIMULTANEOUS OR SEQUENTIAL INTRATHYMIC INOCULATION OF DISPARATE ALLOANTIGENS

1995 • 18 citations

The role of donor class I major histocompatibility complex peptides in the induction of allograft tolerance

1997 • 18 citations