Naturally occurring regulatory T cells show reduced sensitivity toward oxidative stress–induced cell death

Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

2004 • 4,872 citations

Production of large amounts of hydrogen peroxide by human tumor cells.

1991 • 2,465 citations

Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells

2006 • 1,496 citations

The Foxp3+ regulatory T cell: a jack of all trades, master of regulation

2008 • 999 citations

Activated granulocytes and granulocyte-derived hydrogen peroxide are the underlying mechanism of suppression of t-cell function in advanced cancer patients.

2001 • 860 citations

Antigen-Specific Inhibition of CD8+ T Cell Response by Immature Myeloid Cells in Cancer Is Mediated by Reactive Oxygen Species

2004 • 825 citations

Regulatory T cells in cancer

2006 • 717 citations

Human anergic/suppressive CD4+CD25+ T cells: a highly differentiated and apoptosis-prone population

2001 • 460 citations

Outcome in Hodgkin's Lymphoma Can Be Predicted from the Presence of Accompanying Cytotoxic and Regulatory T Cells

2005 • 453 citations

The significance of low bcl-2 expression by CD45RO T cells in normal individuals and patients with acute viral infections. The role of apoptosis in T cell memory.

1993 • 350 citations

In vivo peripheral expansion of naive CD4+CD25highFoxP3+ regulatory T cells in patients with multiple myeloma

2006 • 290 citations

CD4+CD25high Foxp3+ regulatory T cells in myelodysplastic syndrome (MDS)

2007 • 259 citations

Control ofBcl-2expression by reactive oxygen species

2003 • 240 citations

Dysfunctional T regulatory cells in multiple myeloma

2005 • 237 citations

Cutting Edge: In Contrast to Effector T Cells, CD4+CD25+FoxP3+ Regulatory T Cells Are Highly Susceptible to CD95 Ligand- but Not to TCR-Mediated Cell Death

2005 • 171 citations

Naive regulatory T cells: a novel subpopulation defined by resistance toward CD95L-mediated cell death

2006 • 170 citations

Expansion of Human T Regulatory Type 1 Cells in the Microenvironment of Cyclooxygenase 2 Overexpressing Head and Neck Squamous Cell Carcinoma

2007 • 152 citations

Nitric oxide induces CD4⁺CD25⁺Foxp3⁻regulatory T cells from CD4⁺CD25⁻T cells via p53, IL-2, and OX40

2007 • 146 citations

Inhibition of Activated/Memory (CD45RO+) T Cells by Oxidative Stress Associated with Block of NF-κB Activation

2001 • 140 citations

Displacement of Linker for Activation of T Cells from the Plasma Membrane Due to Redox Balance Alterations Results in Hyporesponsiveness of Synovial Fluid T Lymphocytes in Rheumatoid Arthritis

2000 • 139 citations

Surface thiols of human lymphocytes and their changes after in vitro and in vivo activation

1996 • 98 citations

Preferential Cell Death of CD8+ Effector Memory (CCR7−CD45RA−) T Cells by Hydrogen Peroxide-Induced Oxidative Stress

2005 • 97 citations

Analysis of the thiol status of peripheral blood leukocytes in rheumatoid arthritis patients

2007 • 65 citations

The CD16−/CD56bright Subset of NK Cells Is Resistant to Oxidant-Induced Cell Death

2007 • 59 citations

NK cell apoptosis in coronary artery disease

2008 • 37 citations