Keynote address: Integration of cytostatic agents and radiation therapy: A different approach to “proliferating” human tumors

The hazard of accelerated tumor clonogen repopulation during radiotherapy

1988 • 1,592 citations

Radiation Biology in Cancer Research

1980 • 782 citations

Accelerated fractionation vs hyperfractionation: Rationales for several treatments per day

1983 • 418 citations

Effect of estrogens and antiestrogens on growth of human breast cancer cells in athymic nude mice.

1985 • 396 citations

Suramin: an anticancer drug with a unique mechanism of action.

1989 • 370 citations

Radiation biology in cancer research

1978 • 340 citations

Measurement of cell kinetics in human tumours in vivo using bromodeoxyuridine incorporation and flow cytometry

1988 • 310 citations

The influence of the number of fractions and of overall treatment time on local control and late complication rate in squamous cell carcinoma of the larynx

1983 • 289 citations

Effects of tamoxifen on human breast cancer cell cycle kinetics: accumulation of cells in early G1 phase.

1983 • 275 citations

Efficient reversion of simian sarcoma virus-transformation and inhibition of growth factor-induced mitogenesis by suramin.

1986 • 270 citations

Accelerated Fractionation in the Radiation Treatment of Head and Neck Cancer—A Critical Comparison of Different Strategies

1988 • 261 citations

A re-evaluation of split-course technique for squamous cell carcinoma of the head and neck

1980 • 258 citations

Inhibition of tamoxifen-stimulated growth of an MCF-7 tumor variant in athymic mice by novel steroidal antiestrogens.

1989 • 249 citations

Adjuvant chemotherapy with and without tamoxifen in the treatment of primary breast cancer: 5-year results from the National Surgical Adjuvant Breast and Bowel Project Trial.

1986 • 215 citations

What is known about tumour proliferation rates to choose between accelerated fractionation or hyperfractionation?

1985 • 209 citations

Tamoxifen induces accumulation of MCF 7 human mammary carcinoma cells in the G0/G1 phase of the cell cycle

1983 • 208 citations

Impact of improved local control on survival

1986 • 144 citations

Antagonism of chemotherapy-induced cytotoxicity for human breast cancer cells by antiestrogens.

1989 • 130 citations

Cell kinetics in human malignancies studied with in vivo administration of bromodeoxyuridine and flow cytometry.

1988 • 128 citations

Differential ability of antiestrogens to stimulate breast cancer cell (MCF-7) growth in vivo and in vitro.

1989 • 117 citations

Time, dose, and tumor volume relationships in irradiation of squamous cell carcinomas of the base of the tongue

1976 • 116 citations

The use of halogenated thymidine analogs as clinical radiosensitizers: Rationale, current status, and future prospects: Non-hypoxic cell sensitizers

1984 • 110 citations

Human breast cancer cell cycle synchronization by estrogens and antiestrogens in culture.

1984 • 105 citations

Human tumour cell kinetics using a monoclonal antibody against iododeoxyuridine: Intratumour sampling variations

1988 • 104 citations

Effects of oestrogens on cell proliferation and cell cycle kinetics. A hypothesis on the cell cycle effects of antioestrogens

1983 • 96 citations

Effect on growth and cell cycle kinetics of estradiol and tamoxifen on MCF-7 human breast cancer cells grown in vitro and in nude mice.

1989 • 91 citations

Production of Mammastatin, a Tissue-Specific Growth Inhibitor, by Normal Human Mammary Cells

1989 • 88 citations

The radiosensitivity of malignant melanomas part II: Clinical studies

1981 • 85 citations

Tamoxifen-citrate counteracts the antitumor effects of cytotoxic drugs in vitro.

1985 • 83 citations

Potentiation of radiation cytotoxicity by recombinant interferons, a phenomenon associated with increased blockage at the G2-M phase of the cell cycle.

1987 • 77 citations

Postmastectomy Irradiation in High-Risk Breast Cancer Patients: Present status of the Danish Breast Cancer Cooperative Group trials

1988 • 66 citations

Potentiation of radiation injury by interferon*

1982 • 63 citations

Anatagonism of the cytocidal activity and uptake of melphalan by tamoxifen in human breast cancer cells in vitro

1985 • 59 citations

The use of non-hypoxic cell sensitizers in radiobiology and radiotherapy

1986 • 57 citations

In vitro and in vivo studies on potentiation of cytotoxic effects of anticancer drugs or cobalt 60 gamma ray by interferon on human neoplastic cells

1984 • 55 citations

The Proliferative Status And Clonogenic Capacity Of Tumour Cells In A Transplantable Rhabdomyosarcoma Of The Rat Before And After Irradiation With 800 Rad Of X‐Rays

1978 • 55 citations

Radiosensitization of Human Bronchogenic Carcinoma Cells by Interferon Beta

1984 • 54 citations

Heterogeneity of X-ray cytotoxicity in proliferating and quiescent murine mammary carcinoma cells.

1985 • 43 citations

The influence of the number of fractions, overall treatment time and field size on the local control of cancer of the skin

1983 • 43 citations

Impact of improved local control on survival in patients with soft tissue sarcoma

1986 • 42 citations

Short-term variation in labeling index as a predictor of radiotherapy response in human oral cavity carcinoma

1984 • 38 citations

Clonogenic Capacity of Proliferating and Nonproliferating Cells of a Transplantable Rat Rhabdomyosarcoma in Relation to its Radiosensitivity

1973 • 38 citations

Oxygen Enhancement Ratio in V79 Spheroids

1983 • 24 citations

CELL KINETICS OF IRRADIATED EXPERIMENTAL TUMORS: CELL TRANSITION FROM THE NON‐PROLIFERATING TO THE PROLIFERATING POOL

1980 • 24 citations

The cytokinetic basis for the design of efficacious radiotherapy protocols

1979 • 22 citations

The survival of rat mammary gland cells following irradiation in vivo under different endocrinological conditions

1978 • 20 citations

Changes in Bromodeoxyuridine Labeling Index during Radiation Treatment of an Experimental Tumor

1988 • 20 citations

Differences in the X-Ray Sensitivity of Cells in Different Regions of the Sandwich, a Diffusion-Limited System for Cell Growth

1986 • 10 citations

Lack of a differential radiation response for proliferative and non-proliferative rat thyroid cells (FRTL-5) in vitro

1989 • 9 citations

Cell kinetic study in human tumours using iudr labelling and flowcytometry

1989 • 3 citations