A DNA polymerase alpha pause site is a hot spot for nucleotide misinsertion.

The p53 tumour suppressor gene

1991 • 3,871 citations

ras GENES

1987 • 3,818 citations

Escherichia coli thioredoxin confers processivity on the DNA polymerase activity of the gene 5 protein of bacteriophage T7.

1987 • 399 citations

Specificity and Mechanism of Error-prone Replication by Human Immunodeficiency Virus-1 Reverse Transcriptase

1989 • 316 citations

The base substitution fidelity of eucaryotic DNA polymerases. Mispairing frequencies, site preferences, insertion preferences, and base substitution by dislocation.

1986 • 301 citations

Base mispair extension kinetics. Comparison of DNA polymerase alpha and reverse transcriptase.

1990 • 293 citations

Animal Cell Dna Polymerases

1986 • 283 citations

Escherichia coli thioredoxin stabilizes complexes of bacteriophage T7 DNA polymerase and primed templates.

1987 • 207 citations

The mutational specificity of DNA polymerases-alpha and -gamma during in vitro DNA synthesis.

1985 • 176 citations

The fidelity of DNA synthesis catalyzed by derivatives of Escherichia coli DNA polymerase I.

1990 • 169 citations

Extension of mismatched 3' termini of DNA is a major determinant of the infidelity of human immunodeficiency virus type 1 reverse transcriptase.

1989 • 132 citations

Differential extension of 3′ mispairs is a major contribution to the high fidelity of calf thymus DNA polymerase-α

1989 • 129 citations

Specific sequences in native DNA that arrest synthesis by DNA polymerase alpha.

1982 • 125 citations

Size classes of products synthesized processively by two subassemblies of Escherichia coli DNA polymerase III holoenzyme.

1982 • 111 citations

Site-specific pausing of deoxyribonucleic acid synthesis catalyzed by four forms of Escherichia coli DNA polymerase III

1983 • 111 citations

Recent studies of the fidelity of DNA synthesis

1988 • 98 citations

Spectrum of spontaneous mutation at the APRT locus of Chinese hamster ovary cells: an analysis at the DNA sequence level.

1988 • 95 citations

The energy relay: a proofreading scheme based on dynamic cooperativity and lacking all characteristic symptoms of kinetic proofreading in DNA replication and protein synthesis.

1980 • 91 citations

Template-directed pausing in in vitro DNA synthesis by DNA polymerase a from Drosophila melanogaster embryos.

1982 • 87 citations

Influence of template primary and secondary structure on the rate and fidelity of DNA synthesis.

1985 • 48 citations

The DNA polymerase-primase from drosophila melanogaster embryos. Rate and fidelity of polymerization on single-stranded DNA templates.

1984 • 47 citations

Studies on the mechanism of Escherichia coli DNA polymerase I large fragment. Effect of template sequence and substrate variation on termination of synthesis.

1988 • 43 citations

Synthesis of DNA by human immunodeficiency virus reverse transcriptase is preferentially blocked at template oligo(deoxyadenosine) tracts.

1990 • 41 citations

Replication of M13mp7 single‐stranded DNA in vitro by the 9‐S DNA polymerase α from calf thymus

1984 • 29 citations

Rabbit liver factor D, a poly(thymidine) template stimulatory protein of DNA polymerases: purification and characterization

1988 • 21 citations

Sequence specificity of pausing by DNA polymerases

1989 • 18 citations

Template-selective stimulation of diverse DNA polymerases by the murine DNA-binding protein factor D.

1987 • 11 citations

Factor C from Rabbit Liver

1989 • 5 citations