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HUMAN PLASMA PROTEINASE INHIBITORS

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Histologic fixatives suitable for diagnostic light and electron microscopy.

1976 • 1,272 citations

THE DEVELOPMENT OF NEUTROPHILIC POLYMORPHONUCLEAR LEUKOCYTES IN HUMAN BONE MARROW

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Quantitative Methods in the Study of Pulmonary Pathology

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Human leukocyte granule elastase: rapid isolation and characterization

1976 • 550 citations

Elastases and emphysema. Current assessment of the protease-antiprotease hypothesis.

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Cigarette smoking and lung destruction. Accumulation of neutrophils in the lungs of cigarette smokers.

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Antielastases of the human alveolar structures. Implications for the protease-antiprotease theory of emphysema.

1981 • 441 citations

The Induction of Pulmonary Emphysema with Human Leukocyte Elastase^1–3

1977 • 335 citations

Morphologic and morphometric effects of prolonged cigarette smoking on the small airways.

1980 • 295 citations

Experimental emphysema induced with purified human neutrophil elastase: tissue localization of the instilled protease.

1977 • 284 citations

The definition of emphysema. Report of a National Heart, Lung, and Blood Institute, Division of Lung Diseases workshop.

1985 • 281 citations

Neutrophils degrade subendothelial matrices in the presence of alpha-1-proteinase inhibitor. Cooperative use of lysosomal proteinases and oxygen metabolites.

1984 • 253 citations

Proteolysis by Neutrophils

1982 • 244 citations

The polymorphonuclear leukocyte

1978 • 235 citations

Morphology of Peripheral Airways in Current Smokers and Ex-smokers^1–3

1983 • 188 citations

The degradation of human lung elastin by neutrophil proteinases

1980 • 129 citations

Receptor-mediated binding and internalization of leukocyte elastase by alveolar macrophages in vitro.

1979 • 116 citations

Lung phagocyte recruitment and metabolic alterations induced by cigarette smoke in humans and in hamsters.

1982 • 105 citations

Human leukocyte elastase, cathepsin G, and lactoferrin: family of neutrophil granule glycoproteins that bind to an alveolar macrophage receptor.

1982 • 96 citations

Isolation and surface labeling of murine polymorphonuclear neutrophils

1979 • 81 citations

A rapid single centrifugation step method for the separation of erythrocytes, granulocytes and mononuclear cells on continous density gradients of percoll

1980 • 54 citations

Elastases and Emphysema

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The pathogenesis of emphysema--twenty years of progress.

1981 • 43 citations

Induction of experimental emphysema in dogs using leukocyte homogenates.

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A model of decreased functional alpha-1-proteinase inhibitor. Pulmonary pathology of dogs exposed to chloramine T.

1981 • 35 citations

Emphysema induced in vitro and in vivo in dogs by a purified elastase from homologous leukocytes.

1981 • 30 citations

The dose-dependent fate of enzymatically active and inactivated tritiated methylated pancreatic elastase administered intratracheally in the hamster.

1979 • 27 citations

Degradation of Elastin in Experimental Elastase-Induced Emphysema Measured by a Radioimmunoassay for Desmosine

1983 • 20 citations

Synthetic elastase inhibitors: prospects for use in the treatment of emphysema.

1983 • 20 citations

Solid-phase immunoassay of dog neutrophil elastase

1980 • 19 citations

Elastase-induced emphysema: retention of instilled proteinase in the rat.

1982 • 18 citations

Isolation and Partial Characterization of Elastase from Dog Granulocytes

1976 • 17 citations

A comparison of the binding and fate of internalized neutrophil elastase in human monocytes and alveolar macrophages.

1983 • 9 citations

ELECTRON AND LIGHT MICROSCOPIC STUDIES OF THE LUNGS OF CHLORAMINE-T TREATED DOGS

1981 • 6 citations