High-level expression in Escherichia coli of a chemically synthesized gene for [Leu-28]echistatin

[2] New M13 vectors for cloning

1983 • 5,402 citations

Gene Synthesis Machines: DNA Chemistry and Its Uses

1985 • 761 citations

Generation of β-globin by sequence-specific proteolysis of a hybrid protein produced in Escherichia coli

1984 • 374 citations

Echistatin. A potent platelet aggregation inhibitor from the venom of the viper, Echis carinatus.

1988 • 365 citations

Trigramin. A low molecular weight peptide inhibiting fibrinogen interaction with platelet receptors expressed on glycoprotein IIb-IIIa complex.

1987 • 323 citations

Expression of human fibroblast interferon gene in Escherichia coli

1980 • 190 citations

Total synthesis of a gene for bovine rhodopsin.

1986 • 179 citations

Expression of the human fibroblast interferon gene in Escherichia coli.

1980 • 130 citations

Overexpression and sequence of the Escherichia coli cheY gene and biochemical activities of the CheY protein

1984 • 129 citations

Synthesis of biologically active rat transforming growth factor I

1984 • 102 citations

Multiple joined genes prevent product degradation in Escherichia coli.

1984 • 102 citations

Total chemical synthesis of a gene for hepatitis B virus core protein and its functional characterization

1988 • 62 citations

Expression of antigenic determinants of the hemagglutinin gene of a human influenza virus in Escherichia coli.

1981 • 57 citations

[44] Cleavage of the tryptophanyl peptide bond by dimethyl sulfoxide-hydrobromic acid

1977 • 47 citations

Rapid construction of large synthetic genes: total chemical synthesis of two different versions of the bovine prochymosin gene

1987 • 42 citations

High-level expression of α-human atrial natriuretic peptide from multiple joined genes in Escherichia coli

1987 • 37 citations

A General Method for Retrieving the Components of a Genetically Engineered Fusion Protein

1986 • 34 citations

Bacterial Synthesis of Recombinant α-Human Atrial Natriuretic Polypeptide

1987 • 26 citations

Chemical synthesis, cloning and expression in mammalian cells of a gene coding for human tissue-type plasminogen activator

1988 • 20 citations

High-cell-density fermentation studies of a recombinantE. coli that expresses atrial natriuretic factor

1987 • 16 citations

Site-Specific Cleavage of a Fusion Protein by Renin

1987 • 7 citations