Modulation of Eosinophilic Chemotaxis with Azelastine and Budesonide in Allergic Patients

Recombinant human granulocyte-macrophage colony-stimulating factor stimulates in vitro mature human neutrophil and eosinophil function, surface receptor expression, and survival.

1986 • 733 citations

The eosinophil and bronchial asthma: Current understanding

1990 • 688 citations

YERSINIA ENTEROCOLITICA INFECTIONS AND PORK: THE MISSING LINK

1987 • 654 citations

T LYMPHOCYTE ACTIVATION IN ACUTE SEVERE ASTHMA

1988 • 353 citations

Eosinophils, bronchial hyperreactivity and late‐phase asthmatic reactions

1985 • 348 citations

Interleukin-8: an important chemoattractant in sputum of patients with chronic inflammatory airway diseases

1993 • 315 citations

Pharmacokinetics and metabolism of budesonide, a selective glucocorticoid.

1982 • 306 citations

Human Mononuclear Leukocyte Chemotaxis: A Quantitative Assay for Humoral and Cellular Chemotactic Factors

1972 • 290 citations

Comparison of leukocyte counts in sputum, bronchial biopsies, and bronchoalveolar lavage.

1995 • 278 citations

Comparison of samples collected by sputum induction and bronchoscopy from asthmatic and healthy subjects.

1995 • 251 citations

Modulation and induction of eosinophil chemotaxis by granulocyte- macrophage colony-stimulating factor and interleukin-3

1991 • 230 citations

Calcium Influx Requirement for Human Neutrophil Chemotaxis: Inhibition by Lanthanum Chloride

1976 • 222 citations

The Influence of Histamine on Immune and Inflammatory Responses

1984 • 149 citations

Analysis of cellular and biochemical constituents of induced sputum after allergen challenge: A method for studying allergic airway inflammation

1994 • 147 citations

Interleukin-8 is a potent mediator of eosinophil chemotaxis through endothelium and epithelium

1995 • 140 citations

Upregulation of formyl-peptide and interleukin-8—induced eosinophil chemotaxis in patients with allergic asthma

1993 • 125 citations

Inhibition of calcium ionophore (A23187)-stimulated histamine release from rat peritoneal mast cells by azelastine: Implications for its mode of action

1983 • 124 citations

A Chemotactic Factor for Mononuclear Leukocytes

1971 • 116 citations

Histamine regulates lymphocyte mitogenic responses through activation of specific H1 and H2 histamine receptors.

1980 • 103 citations

Chemotactic agonists induce cytokine generation in eosinophils.

1995 • 83 citations

Effects of a Corticosteroid, Budesonide, on Alveolar Macrophage and Blood Monocyte Secretion of Cytokines: Differential Sensitivity of GM-CSF, IL-1β, and IL-6

1994 • 80 citations

IL‐5, IL‐8 and GM‐CSF immunostaining of sputum cells in bronchial asthma and chronic bronchitis

1995 • 72 citations

Clinical significance of measuring levels of sputum and serum ECP and serum IL‐5 in bronchial asthma

1993 • 64 citations

The inhibitory actions of azelastine hydrochloride on the early and late bronchoconstrictor responses to inhaled allergen in atopic asthma

1989 • 49 citations

Inhibition of Leukotriene (SRS‐A)‐Mediated Acute Lung Anaphylaxis by Azelastine in Guinea Pigs

1986 • 47 citations

Polymorphonuclear leukocyte motility in vitro. VI. Effect of purine and pyrimidine analogues: possible role of cyclic AMP.

1972 • 45 citations

The effects of the potent glucocorticoid budesonide on adhesion of eosinophils to human vascular endothelial cells and on endothelial expression of adhesion molecules.

1993 • 45 citations

Isolation of human eosinophils and their lymphocyte-like rosetting properties.

1976 • 39 citations

The effects of β₂‐adrenoceptor agonists and a corticosteroid, budesonide, on the secretion of inflammatory mediators from monocytes

1992 • 33 citations

Effect of azelastine on platelet-activating factor and antigen-induced pleurisy in rats

1991 • 32 citations

T cells and asthma. II. Regulation of the eosinophilia of asthma by T cell cytokines.

1991 • 28 citations

Antiallergic properties of the second-generation H antihistamines during the early and late reactions to antigen

1992 • 25 citations

Inhibitory effects of azelastine hydrochloride on Ca²⁺influx, actin polymerization and release of eosinophil cationic protein of an eosinophilic leukaemia cell line EoL-1

1993 • 20 citations

Budesonide inhibits T cell-initiated epithelial pathophysiology in an in vitro model of inflammation.

1996 • 17 citations

Inhibition of Aeroallergen-lnduced Bronchial Eosinophilia by Azelastine in Guinea Pigs

1992 • 14 citations

Effects of “systemic” budesonide concentrations on in vitro allergen‐induced activation of blood mononuclear cells isolated from asthmatic patients

1995 • 14 citations

T Cells and Asthma

1991 • 9 citations

The activity of recent anti-allergic drugs in the treatment of seasonal allergic rhinitis.

1996 • 9 citations

Allergic bronchial asthma: eosinophil chemotaxis and antihistaminic drug modulation

1996 • 4 citations

Allergic bronchial asthma: eosinophil chemotaxis and antihistaminic drug modulation

1996 • 3 citations