Can the stereoselective effects of the anesthetic isoflurane be accounted for by lipid solubility?

COMPARATIVE PHARMACOLOGY OF THE KETAMINE ISOMERS

1985 • 382 citations

Stereospecific Effects of Inhalational General Anesthetic Optical Isomers on Nerve Ion Channels

1991 • 284 citations

SELECTIVE ACTIONS OF VOLATILE GENERAL ANAESTHETICS AT MOLECULAR AND CELLULAR LEVELS

1993 • 216 citations

The Nature of The Site of General Anesthesia

1985 • 205 citations

Comparative pharmacology of the optical isomers of ketamine in mice

1978 • 192 citations

Effects of volatile anesthetics on the kinetics of inhibitory postsynaptic currents in cultured rat hippocampal neurons

1993 • 177 citations

Differential effects of ketamine enantiomers on NMDA receptor currents in cultured neurons

1992 • 132 citations

Effects of optical isomers of ketamine on excitation of cat and rat spinal neurones by amino acids and acetylcholine

1982 • 127 citations

Pentobarbital: Stereospecific Actions of (+) and (-) Isomers Revealed on Cultured Mammalian Neurons

1980 • 104 citations

Barbiturates: Their in vivo effects and potential biochemical mechanisms

1982 • 96 citations

The solubility of anesthetic gases in lipid bilayers

1981 • 82 citations

Halothane Binding to Soluble Proteins Determined by Photoaffinity Labeling

1993 • 82 citations

Isoflurane anesthesia is stereoselective

1992 • 80 citations

The effects of delta1-tetrahydrocannabinol and other cannabinoids on spin-labeled liposomes and their relationship to mechanisms of general anesthesia.

1975 • 79 citations

Inhalational Anesthetics Stereochemistry: Optical Resolution of Halothane, Enflurane, and Isoflurane

1991 • 65 citations

Stereospecific actions of the inhalation anesthetic isoflurane at the GABAA receptor complex

1993 • 63 citations

Membrane interactions with general and local anaesthetics: A review of molecular hypotheses of anaesthesia

1983 • 60 citations

The osmotic insensitivity of sonicated liposomes and the density of phospholipid-cholesterol mixtures

1973 • 57 citations

Structural Specificity of Barbiturates and Related Drugs

1982 • 55 citations

Actions of General Anesthetics on Acetylcholine Receptor-rich Membranes from Torpedo californica

1986 • 50 citations

Halothane Stereoisomers

1973 • 28 citations

Stereoselectivity of Channel Inhibition by Secondary Alkanol Enantiomers at Nicotinic Acetylcholine Receptors

1993 • 19 citations