The differential interaction of p38 MAP kinase and tumor necrosis factor-α in human alveolar macrophages and monocytes induced by Mycobacterium tuberculois

A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

1994 • 3,285 citations

NF-κB: Ten Years After

1996 • 3,008 citations

Cell Activation and Apoptosis by Bacterial Lipoproteins Through Toll-like Receptor-2

1999 • 1,500 citations

Global epidemiology of tuberculosis. Morbidity and mortality of a worldwide epidemic

1995 • 1,315 citations

Toll-like receptor-2 mediates mycobacteria-induced proinflammatory signaling in macrophages

1999 • 829 citations

Global Epidemiology of Tuberculosis

1995 • 782 citations

The p38 Mitogen-activated Protein Kinase Is Required for NF-κB-dependent Gene Expression

1999 • 444 citations

Chemokine receptor 2 serves an early and essential role in resistance toMycobacterium tuberculosis

2001 • 324 citations

Both Erk and p38 Kinases Are Necessary for Cytokine Gene Transcription

1999 • 305 citations

Osmotic regulation of cytokine synthesis in vitro.

1995 • 282 citations

Complement receptor-mediated uptake and tumor necrosis factor-alpha-mediated growth inhibition of Mycobacterium tuberculosis by human alveolar macrophages.

1994 • 260 citations

Differential expression of Toll-like receptor 2 in human cells

2001 • 248 citations

Lipopolysaccharide Signals Activation of Tumor Necrosis Factor Biosynthesis Through the Ras/Raf-1/MEK/MAPK Pathway

1994 • 228 citations

Selective induction of transforming growth factor beta in human monocytes by lipoarabinomannan of Mycobacterium tuberculosis

1996 • 176 citations

Enhancement Of Intracellular Growth Of Mycobacterium Tuberculosis In Human Monocytes by Transforming Growth Factor- l

1994 • 172 citations

Induction of Inducible Nitric Oxide Synthase-NO· by Lipoarabinomannan ofMycobacterium tuberculosisIs Mediated by MEK1-ERK, MKK7-JNK, and NF-κB Signaling Pathways

2001 • 169 citations

Expression of Virulence ofMycobacterium tuberculosiswithin Human Monocytes: Virulence Correlates with Intracellular Growth and Induction of Tumor Necrosis Factor Alpha but Not with Evasion of Lymphocyte-Dependent Monocyte Effector Functions

1998 • 128 citations

Toll-like receptor 2 is expressed by alveolar epithelial cells type II and macrophages in the human lung

2003 • 120 citations

p38 Mitogen-Activated Protein Kinase Inhibition Increases Cytokine Release by Macrophages In Vitro and During Infection In Vivo

2001 • 110 citations

Requirement of Mitogen-Activated Protein Kinases and IκB Phosphorylation for Induction of Proinflammatory Cytokines Synthesis by Macrophages Indicates Functional Similarity of Receptors Triggered by Glycosylphosphatidylinositol Anchors from Parasitic Protozoa and Bacterial Lipopolysaccharide

2001 • 110 citations

Activation of the Mitogen-Activated Protein Kinase Signaling Pathway Is Instrumental in Determining the Ability ofMycobacterium aviumto Grow in Murine Macrophages

2002 • 88 citations

Tumor necrosis factor alpha (TNFalpha) promotes growth of virulent Mycobacterium tuberculosis in human monocytes iron-mediated growth suppression is correlated with decreased release of TNFalpha from iron-treated infected monocytes.

1997 • 85 citations

T Lymphocytic and Immature Macrophage Alveolitis in Active Pulmonary Tuberculosis

1996 • 64 citations

Control of Mycobacterial Replication in Human Macrophages: Roles of Extracellular Signal-Regulated Kinases 1 and 2 and p38 Mitogen-Activated Protein Kinase Pathways

2002 • 64 citations

Colonial morphotype as a determinant of cytokine expression by human monocytes infected with Mycobacterium avium.

1993 • 62 citations

Induction of monocyte expression of tumor necrosis factor alpha by the 30-kD alpha antigen of Mycobacterium tuberculosis and synergism with fibronectin.

1996 • 60 citations

Genetic Deletion of the Tumor Necrosis Factor Receptor p60 or p80 Abrogates Ligand-mediated Activation of Nuclear Factor-κB and of Mitogen-activated Protein Kinases in Macrophages

2001 • 58 citations

A Human Whole‐Blood Assay for Analysis of T‐Cell Function by Quantification of Cytokine mRNA

1999 • 57 citations

Toll-like receptor 2 (TLR2) mediates activation of stress-activated MAP kinase p38

2002 • 48 citations