High Activities of Glutamine Transaminase K (Dichlorovinylcysteine β‐Lyase) and ω‐Amidase in the Choroid Plexus of Rat Brain

“Western Blotting”: Electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A

1981 • 8,657 citations

The Use of Antiavidin Antibody and Avidin-Biotin-Peroxidase Complex in Immunoperoxidase Technics

1981 • 1,067 citations

Kinetics of Neutral Amino Acid Transport Across the Blood‐Brain Barrier

1987 • 441 citations

Biosynthesis and biotransformation of glutathioneS-Conjugates to toxic metabolites

1988 • 193 citations

TRANSAMINATION AND ASSOCIATED DEAMIDATION OF ASPARAGINE AND GLUTAMINE

1952 • 153 citations

A purified cysteine conjugate beta-lyase from rat kidney cytosol. Requirement for an alpha-keto acid or an amino acid oxidase for activity and identity with soluble glutamine transaminase K.

1986 • 153 citations

Isolation and Properties of a New Glutamine Transaminase from Rat Kidney

1974 • 135 citations

Renal cysteine conjugate beta-lyase. Bioactivation of nephrotoxic cysteine S-conjugates in mitochondrial outer membrane.

1986 • 122 citations

Bioactivation of xenobiotics by formation of toxic glutathione conjugates

1991 • 105 citations

Polyneuritis cranialis associated with industrial trichloroethylene poisoning.

1967 • 105 citations

The mechanism of cysteine conjugate cytotoxicity in renal epithelial cells. Covalent binding leads to thiol depletion and lipid peroxidation.

1990 • 97 citations

Purification and characterization of human kidney cytosolic cysteine conjugate beta-lyase activity.

1990 • 89 citations

Thioacylating intermediates as metabolites of S-(1,2-dichlorovinyl)-L-cysteine and S-(1,2,2-trichlorovinyl)-L-cysteine formed by cysteine conjugate .beta.-lyase

1988 • 81 citations

Regulation of renal ammoniagenesis. Purification and characterization of phosphate-dependent glutaminase from rat kidney.

1976 • 80 citations

Cysteine conjugate toxicity, metabolism, and binding to macromolecules in isolated rat kidney mitochondria.

1990 • 79 citations

The γ-Glutamyl Cycle in the Choroid Plexus: Its Possible Function in Amino Acid Transport

1973 • 79 citations

TRANSAMINATION OF AMINO ACIDS IN HOMOGENATES OF RAT BRAIN

1971 • 75 citations

Immunohistochemical localization of glutamine transaminase K, a rat kidney cysteine conjugate beta-lyase, and the relationship to the segment specificity of cysteine conjugate nephrotoxicity.

1988 • 73 citations

Transport of neutral amino acids from feline cerebrospinal fluid

1969 • 73 citations

The role of mitochondrial matrix enzymes in the metabolism and toxicity of cysteine conjugates.

1988 • 71 citations

Comparative studies of glutamine transaminases from rat tissues

1981 • 65 citations

Ventriculo–cisternal perfusion of twelve amino acids in the rabbit

1982 • 64 citations

Regulation of renal ammoniagenesis

1976 • 63 citations

Purification of soluble and mitochondrial glutamine transaminase K from rat kidney

1978 • 59 citations

Cysteine conjugate β-lyase of rat kidney cytosol: Characterization, immunocytochemical localization, and correlation with hexachlorobutadiene nephrotoxicity

1989 • 58 citations

Detection of cysteine conjugate metabolite adduct formation with specific mitochondrial proteins using antibodies raised against halothane metabolite adducts.

1991 • 57 citations

REGIONAL AND SUBCELLULAR DISTRIBUTION OF AMINOTRANSFERASES IN RAT BRAIN

1972 • 57 citations

Bioactivation mechanism of the cytotoxic and nephrotoxic S-conjugate S-(2-chloro-1,1,2-trifluoroethyl)-L-cysteine.

1987 • 57 citations

Isolation and expression of a cDNA coding for rat kidney cytosolic cysteine conjugate beta-lyase.

1993 • 55 citations

Metabolism of the nephrotoxin dichloroacetylene by glutathione conjugation

1989 • 55 citations

Identification of α-Ketoglutaramate in Rat Liver, Kidney, and Brain

1974 • 54 citations

Transport of amino acids by rabbit choroid plexus in vitro

1971 • 45 citations

Alpha-ketoacids stimulate rat renal cysteine conjugate beta-lyase activity and potentiate the cytotoxicity of S-(1,2-dichlorovinyl)-L-cysteine.

1987 • 44 citations

Thioacylating agents as ultimate intermediates in the β-lyase catalysed metabolism of S-(pentachlorobutadienyl)-L-cysteine

1988 • 43 citations

Triple-column ion-exchange physiological amino acid analysis with fluorescent detection: Baseline characterization of human cerebrospinal fluid

1984 • 43 citations

Neutral amino acid uptake by the isolated perfused sheep choroid plexus.

1989 • 42 citations

THE GLUTAMINE TRANSAMINASE‐ω‐AMIDASE SYSTEM IN RAT AND HUMAN BRAIN¹

1977 • 40 citations

Glutamine Transaminase K and Cysteine Conjugate β‐Lyase^a

1990 • 38 citations

A New Hazard in Closed Environmental Atmospheres

1967 • 35 citations

Brain uptake of S-(1,2-dichlorovinyl)glutathione and , the glutathione and cysteine S-conjugates of the neurotoxin dichloroacetylene

1993 • 34 citations

Metabolism of¹⁴C-dichloroethyne in rats

1991 • 31 citations

In vivo detection and characterization of protein adducts resulting from bioactivation of haloethene cysteine S-conjugates by fluorine-19 NMR: chlorotrifluoroethene and tetrafluoroethene

1992 • 30 citations

Transamination of l-cystathionine and related compounds by bovine brain glutamine transaminase

1987 • 30 citations

Glutamine transaminase K and cysteine S-conjugate β-lyase activity stains

1991 • 26 citations

Highly Purified Glutamine Transaminase from Rat Brain

1975 • 25 citations

Formation of dichloroacetylene from trichloroethylene in the presence of alkaline material — possible cause of intoxication after abundant use of chloroethylene-containing solvents

1984 • 24 citations

Glutamine Transaminase from Brain Tissue. Further Studies on Kinetic Properties and Specificity of the Enzyme

1976 • 19 citations

[45] α-keto acid ω-amidase from rat liver

1985 • 18 citations

Nephrotoxic Amino Acid and Glutathione S-Conjugates: Formation and Renal Activation

1986 • 15 citations

Is the Toxicity of Cysteine Conjugates Formed During Mercapturic Acid Biosynthesis Relevant to the Toxicity of Covalently Bound Drug Residues?

1990 • 14 citations

Steady-state distribution of cycloleucine and α-aminoisobutyric acid between plasma and cerebrospinal fluid

1986 • 12 citations

A PHARMACOLOGICAL ASPECT ON GLUTAMIC ACID METABOLISM IN BRAIN

1957 • 12 citations

Fluorometric determination of α-ketosuccinamic acid in rat tissues

1987 • 12 citations

Glutamine transaminase and ω‐amidase: species variations in brain activity and effect of portacaval shunting¹

1977 • 9 citations

Malaria Vaccine on Trial at Last?

1992 • 7 citations

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