Pargyline and deprenyl prevent the neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in monkeys

Chronic Parkinsonism in Humans Due to a Product of Meperidine-Analog Synthesis

1983 • 4,822 citations

A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

1983 • 2,149 citations

Metabolism of the neurotoxic tertiary amine, MPTP, by brain monoamine oxidase

1984 • 1,092 citations

The pathobiology of Parkinson's disease: biochemical aspects of dopamine neuron senescence.

1983 • 224 citations

1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Destroys Dopamine Neurons in Explants of Rat Embryo Mesencephalon

1984 • 113 citations