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The reductive metabolism of halogenated alkanes by liver microsomal cytochrome P450

Data up to Jan 2025

Published1982
Citations91
References27

Total Citations Per Year

Abstract

References (27)

DETERMINATION OF SERUM PROTEINS BY MEANS OF THE BIURET REACTION

1949 • 16,078 citations

The Carbon Monoxide-binding Pigment of Liver Microsomes

1964 • 11,832 citations

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Binding of14C-Carbon Tetrachloride to Microsomal Proteinsin vitroand Formation of CHCl3by Reduced Liver Microsomes

1973 • 177 citations

An Animal Model of Halothane Hepatotoxicity

1979 • 172 citations

Hydroxylation of Aliphatic Compounds by Liver Microsomes, I. The Distribution Pattern of Isomeric Alcohols

1970 • 125 citations

Volatile Metabolites and Decomposition Products of Halothane In Man

1979 • 116 citations

The mechanism of chloroform and carbon monoxide formation from carbon tetrachloride by microsomal cytochrome P-450

1980 • 114 citations

Metabolic activation of halothane and its covalent binding to liver endoplasmic proteins in vitro

1973 • 105 citations

Metyrapone interaction with hepatic microsomal cytochrome P-450 from rats treated with phenobarbital

1969 • 98 citations

Biotransformation and hepatotoxicity of halothane

1977 • 89 citations

Effect of oxygen concentration on the reaction of halothane with cytochrome P450 in liver microsomes and isolated perfused rat liver

1978 • 88 citations

Studies on the mechanism of action of mammalian hepatic azoreductase—II

1967 • 87 citations

The mechanism of halothane binding to microsomal cytochrome P450

1974 • 86 citations

Participation of Cytochrome P-450 in the Reduction of Nitro Compounds by Rat Liver Microsomes

1980 • 78 citations

Cytochrome b5 as Electron Donor for Oxy‐cytochrome P‐450

1981 • 62 citations

Enzymic Reduction of Aromatic Hydrocarbon Epoxides by the Microsomal Fraction of Rat Liver

1975 • 51 citations

O2‐independent damage of cytochrome P450 by CCl4‐metabolites in hepatic microsomes

1980 • 48 citations

Trifluoroacetic acid as metabolite of halothane

1964 • 47 citations

Metabolic Activation of Carbon Tetrachloride to a Free-Radical Product: Studies using a Spin Trap

1978 • 46 citations

Some hepatotoxic actions of hexachloroethane and its metabolites in sheep

1969 • 28 citations

Spectral interactions of a series of chlorinated hydrocarbons with cytochrome P‐450 of liver microsomes from variously‐treated rats

1975 • 28 citations

Metabolism of Pentachloroethane in the Mouse

1971 • 22 citations

The Binding of Trichlorofluoromethane and other Haloalkanes to Cytochrome P-450 under Aerobic and Anaerobic Conditions

1976 • 19 citations

Kinetische Untersuchungen zur Hydroxylierung von Cumarin mit Lebermikrosomen von Kaninchen

1966 • 11 citations

[Kinetic studies on the hydroxylation of coumarin with liver microsomes from rabbits].

1965 • 11 citations

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The reductive metabolism of halogenated alkanes by liver microsomal cytochrome P450 (1982) – Biochemical Pharmacology | Metascience Observatory Explorer