Neurophysiological and endocrine consequences of immune activity

Hypothalamic Integration: Organization of the Paraventricular and Supraoptic Nuclei

1983 • 1,962 citations

Organization of Ovine Corticotropin-Releasing Factor Immunoreactive Cells and Fibers in the Rat Brain: An Immunohistochemical Study

1983 • 1,954 citations

Immunoregulatory Feedback Between Interleukin-1 and Glucocorticoid Hormones

1986 • 1,521 citations

β-Endorphin and Adrenocorticotropin Are Selected Concomitantly by the Pituitary Gland

1977 • 1,426 citations

The rat forebrain in stereotaxic coordinates

1959 • 1,391 citations

Corticotropin-Releasing Factor-Producing Neurons in the Rat Activated by Interleukin-1

1987 • 1,152 citations

Noradrenergic and peptidergic innervation of lymphoid tissue

1985 • 996 citations

Behaviorally Conditioned Immunosuppression

1975 • 990 citations

Corticosteroid‐Mediated Immunoregulation in Man

1982 • 902 citations

Hypothalamic Control of Adrenocorticotropin Secretion: Advances since the Discovery of 41-Residue Corticotropin-Releasing Factor

1986 • 874 citations

Production of prostaglandin E and an interleukin-1 like factor by cultured astrocytes and C6 glioma cells.

1982 • 754 citations

The limbic system

1974 • 751 citations

Corticosteroids inhibit murine macrophage Ia expression and interleukin 1 production.

1982 • 665 citations

DETERMINATION OF CATECHOLAMINES IN RAT BRAIN PARTS BY REVERSE‐PHASE ION‐PAIR LIQUID CHROMATOGRAPHY

1978 • 586 citations

Central Noradrenergic Pathways for the Integration of Hypothalamic Neuroendocrine and Autonomic Responses

1981 • 579 citations

Glucocorticoid-induced inhibition of T cell growth factor production. I. The effect on mitogen-induced lymphocyte proliferation.

1979 • 567 citations

Visualization and characterization of interleukin 1 receptors in brain.

1987 • 451 citations

Sleep-promoting effects of endogenous pyrogen (interleukin-1)

1984 • 450 citations

The Immune Response Evokes Changes in Brain Noradrenergic Neurons

1983 • 442 citations

Network of immune-neuroendocrine interactions.

1977 • 413 citations

Central nervous system effects of hypothalamic hormones and other peptides

1979 • 380 citations

Short Papers

1977 • 360 citations

Human lymphocyte production of corticotropin and endorphin-like substances: association with leukocyte interferon.

1981 • 358 citations

Neural Modulation of Immunity

1985 • 353 citations

Changes in Blood Hormone Levels during the Immune Response

1975 • 342 citations

Interferons in the treatment of human cancer.

1984 • 334 citations

Facilitation of Immunoreactive Corticotropin-Releasing Factor Secretion into the Hypophysial-Portal Circulation after Activation of Catecholaminergic Pathways or Central Norepinephrine Injection*

1987 • 324 citations

Human leukocyte interferon: structural and biological relatedness to adrenocorticotropic hormone and endorphins.

1980 • 275 citations

Activation of Mouse T-Helper Cells Induces Abundant Preproenkephalin mRNA Synthesis

1986 • 269 citations

Human leukocytic pyrogen: purification and development of a radioimmunoassay.

1977 • 269 citations

Virus-Induced Corticosterone in Hypophysectomized Mice: A Possible Lymphoid Adrenal Axis

1982 • 266 citations

Emotions, Immunity, And Disease

1964 • 250 citations

Glucocorticoid-induced inhibition of T cell growth factor production. II. The effect on the in vitro generation of cytolytic T cells.

1979 • 244 citations

Neuropsychiatric Manifestations of Human Leukocyte Interferon Therapy in Patients With Cancer

1984 • 244 citations

Studies on the bioperiodicity of the immune response. I. Circadian rhythms of human T, B, and K cell traffic in the peripheral blood.

1981 • 242 citations

Stress and Antibody Response in Rats

1969 • 233 citations

Peptide hormones shared by the neuroendocrine and immunologic systems

1985 • 226 citations

Neurological effects of recombinant human interferon.

1983 • 225 citations

Comparison of firing patterns in oxytocin- and vasopressin-releasing neurones during progressive dehydration

1978 • 224 citations

Psychoneuroimmunology: Interactions between central nervous system and immune system

1987 • 223 citations

Interferons with Special Emphasis on the Immune System

1983 • 211 citations

Human leukocyte interferon (HuIFN-α): Potent endorphin-like opioid activity

1981 • 207 citations

Biology of Opioid Peptides

1979 • 185 citations

Early Experience and Immunity

1968 • 180 citations

How corticosteroids work*1, *2

1975 • 177 citations

Genetic defect in responsiveness to the B cell mitogen lipopolysaccharide

1977 • 173 citations

Specific insulin binding site on T and B lymphocytes as a marker of cell activation

1978 • 170 citations

Neuro-Endocrine Correlates of Immune Response

1973 • 169 citations

Hypothalamic mechanisms in thermoregulation.

1981 • 168 citations

Sympathetic innervation of lymph nodes in mice

1984 • 162 citations

The physiologic, metabolic, and immunologic actions of interleukin-1

1987 • 128 citations

Mechanisms of Histamine Release in Anaphylactic and Anaphylactoid Reactions

2015 • 122 citations

Studies of the bioperiodicity of the immune response. II. Co-variations of murine T and B cells and a role of corticosteroid.

1981 • 118 citations

Histamine and the hypothalamus

1983 • 117 citations

Histamine neuronal pathways and their functions

1987 • 111 citations

Does the immune system communicate with the central nervous system?

1985 • 108 citations

Pyretics and Antipyretics

1982 • 107 citations

Inhibition of in Vitro Lymphokine Synthesis by Glucocorticosteroids

1975 • 97 citations

Neuroanatomy of lymphoid tissue: a review.

1985 • 95 citations

A Comparison of the Pituitary Adrenal Activity Elicited by Electrical Stimulation of Preoptic, Amygdaloid and Hypothalamic Sites in the Rat Brain

1973 • 93 citations

The stress-induced response of the septo-hippocampal cholinergic system. A vectorial outcome of psychoneuroendocrinological interactions

1987 • 92 citations

Alterations of monoamines in specific central autonomic nuclei following immunization in mice

1987 • 91 citations

Adrenal Steroids and Behavioral Adaptation: Relationship to Brain Corticoid Receptors

1982 • 90 citations

The Activating Effect of Histamine On The Central Nervous System

1970 • 89 citations

Effects of hormones and vaginal stimulation on the EEG and hypothalamic units in rats

1967 • 84 citations

Neuroendocrine and metabolic responses induced by Interleukin‐1

1987 • 81 citations

In vitro stimulation of glia cells by a lymphocyteproduced factor

1980 • 79 citations

Iontophoretic application of glucocorticoids inhibits identified neurones in the rat paraventricular nucleus

1988 • 71 citations

Cortisol stimulation by recombinant interferon-α2

1986 • 71 citations

Neuroendocrine regulation of immune processes: Change in circulating corticosterone levels induced by the primary antibody response in mice

1983 • 69 citations

Anatomical Distribution of Corticosterone-Concentrating Neurons in Rat Brain1

2015 • 68 citations

Enkephalins: immunomodulators.

1985 • 67 citations

Hypophyseotropic regulation of adenohypophyseal adrenocorticotropin secretion.

1985 • 65 citations

Influence of medial preoptic‐anterior hypothalamic area stimulation of the excitability of mediobasal hypothalamic neurones in the rat.

1977 • 64 citations

Effects of septal and hippocampal stimuli on paraventricular nucleus neurons

1987 • 63 citations

Interferon and adrenocorticotropic hormone induction of steroidogenesis, melanogenesis and antiviral activity

1981 • 61 citations

Effects of Stimulation of the Preoptic Area on Hypothalamic Paraventricular Nucleus Unit Activity and Corticosterone Secretion in Freely Moving Rats

1986 • 61 citations

The Role of Brain Peptides in Neuroimmunomodulation

1987 • 59 citations

Multiunit electrical activity in conscious rats during an immune response

1987 • 59 citations

Biological and clinical properties of THF.

1985 • 59 citations

Mechanisms by which stressful stimuli activate the pituitary-adrenal system.

1985 • 53 citations

D-Ala²-Met-Enkephalinamide, a Potent Opioid Peptide, Alters Pituitary-Adrenocortical Secretion in Rats*

1982 • 50 citations

Electrophysiology of limbic forebrain and paraventricular nucleus connections

1986 • 47 citations

The Immune System "Belongs in the Body"

1985 • 45 citations

Naloxone blocks the interferon-α induced changes in hypothalamic neuronal activity

1987 • 45 citations

Interferon modifies EEG and EEG-like activity recorded from sensory, motor, and limbic system structures in freely behaving rats.

1983 • 44 citations

Alpha adrenergic system in medial preoptic area involved in sleep-wakefulness in rats

1986 • 43 citations

THE EFFECT OF PITUITARY STALK SECTION ON THE ADRENAL FUNCTION OF WOMEN WITH CANCER OF THE BREAST*

1960 • 36 citations

Catecholamine-containing neurons and lymphoid cells in a lacrimal gland of the pigeon

1985 • 34 citations

Effects of neural stimuli on paraventricular nucleus neurones

1985 • 34 citations

Variation in Adrenal Cortical Hormones Within Physiologic Ranges, Stress and Interferon Production in Mice.

1967 • 33 citations

Electrophysiology of the Anterior Hypothalamus: Thermoregulation and Fever

1982 • 29 citations

Steroid hormones and the brain: Cellular mechanisms underlying neural and behavioral plasticity

1980 • 29 citations

Globulins and behavior in schizophrenia.

1966 • 28 citations

Role of Neurotransmitters and Electrophysiological Changes in the Hypothalamus Related to Central Adrenocortical Regulation

1985 • 26 citations

Electrophysiological Analysis of Brain Reactions to Antigen

1987 • 24 citations

Bayliss‐Starling Memorial Lecture (1982). Induction of sleep by muramyl peptides.

1983 • 24 citations

Electrophysiological indications of a ‘vasopressinergic’ innervation of the median eminence

1978 • 24 citations

Neurophysiological changes in the brain following central administration of immunomodulatory factors.

1988 • 23 citations

Feedback Actions of Adrenal Steroid Hormones

1982 • 22 citations

Interferon as a biological response modifying agent in clinical trials.

1983 • 22 citations

Cortisol alters firing rate and synaptic responses of limbic forebrain units

1987 • 21 citations

Influence of some drugs on the immune response. IV. Effect of serotonin, 5-hydroxytryptophan, iproniazid and p-chlorphenylalanine on the synthesis of IgM and IgG antibodies

1973 • 20 citations

Effect of Hypothalamic Lesions on Experimental Autoimmune Diseases in Rats

1987 • 19 citations

INTRODUCTION TO THE EXTRAHYPOTHALAMIC STRUCTURES IN NEUROENDOCRINE REGULATION

1981 • 19 citations

Enkephalins-endorphins: Immunomodulators in mice

1982 • 18 citations

A Neurophysiological Correlate of an Immune Response^a

1987 • 17 citations

Interferons and cancer therapy

1983 • 16 citations

Electrophysiological Mapping of Brain Sites Sensitive to Corticosteroids, ACTH, and Hypothalamic Releasing Hormones

2015 • 15 citations

CHANGES IN THE CONCENTRATION OF CORTICOSTERONE IN THE BLOOD DURING SKIN-GRAFT REJECTION IN THE RAT

1978 • 15 citations

Bursting activity in tuberoinfundibular neurones during electrical stimulation of the rostral hypothalamus

1980 • 15 citations

The Neuropharmacology of Immune Complex Activity in the Rat Hypothalamus

1987 • 14 citations

Effects of treatment with immunomodulatory drugs on thymus and spleen lymphocyte subpopulations and serum corticosterone levels

1982 • 13 citations

Neuroendocrine correlates of stress

1986 • 12 citations

ELECTRICAL ACTIVITY OF ANTIDROMICALLY IDENTIFIED TUBEROINFUNDIBULAR NEURONES DURING STIMULATED RELEASE OF LUTEINIZING HORMONE AND PROLACTIN IN PRO-OESTROUS RATS

1981 • 11 citations

Technique for Recording Multiple-Unit Activity from the Brain of the Freely-Moving Rat

1972 • 11 citations

Adrenocortical Responses in Dexamethasone-Treated Rats with Septal, Preoptic and Combined Hypothalamic Lesions

1980 • 11 citations

Nucleus accumbens and preoptic area stimulation: tuberoinfundibular single unit responses, modulation of electrical activity and gonadotrophin secretion

1985 • 7 citations

Effects of some antineoplastic agents on plasma levels of corticosterone, prolactin and thyroid stimulating hormone.

1977 • 4 citations

A Three-Level Amplitude Discriminator for the Separation of Multi-Unit Electrophysiological Information

1987 • 3 citations

Electrophysiological changes in brain during immune response

1988 • 2 citations