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Identification of a T Helper Cell-Derived Lymphokine That Activates Resting T Lymphocytes

Data up to Jan 2025

Published1986
Citations52
References66

Total Citations Per Year

Abstract

References (66)

Cloning, sequence and expression of two distinct human interleukin-1 complementary DNAs

1985 • 1,594 citations

A human T cell-specific cDNA clone encodes a protein having extensive homology to immunoglobulin chains

1984 • 1,262 citations

Isolation of cDNA clones encoding T cell-specific membrane-associated proteins

1984 • 1,239 citations

An alternative pathway of T-cell activation: A functional role for the 50 kd T11 sheep erythrocyte receptor protein

1984 • 1,132 citations

Nucleotide sequence of human monocyte interleukin 1 precursor cDNA.

1984 • 1,042 citations

The Interleukin-2 T-Cell System: A New Cell Growth Model

1984 • 935 citations

Cloning and expression of murine interleukin-1 cDNA in Escherichia coli

1984 • 820 citations

Transmembrane signalling by the T cell antigen receptor. Perturbation of the T3-antigen receptor complex generates inositol phosphates and releases calcium ions from intracellular stores.

1985 • 742 citations

OKT3: A monoclonal anti-human T lymphocyte antibody with potent mitogenic properties

1980 • 718 citations

Human T-lymphotropic retroviruses

1985 • 623 citations

Transient expression of interleukin 2 receptors. Consequences for T cell growth.

1983 • 613 citations

Tumor-specific antigen of murine T-lymphoma defined with monoclonal antibody.

1982 • 526 citations

OKT3: a monoclonal anti-human T lymphocyte antibody with potent mitogenic properties.

1980 • 525 citations

Triggering of the T3-Ti antigen-receptor complex results in clonal T-cell proliferation through an interleukin 2-dependent autocrine pathway.

1984 • 506 citations

Antigen recognition by human T lymphocytes is linked to surface expression of the T3 molecular complex

1982 • 494 citations

A third type of murine T-cell receptor gene

1984 • 491 citations

Role of T3 surface molecules in human T-cell activation: T3-dependent activation results in an increase in cytoplasmic free calcium.

1984 • 452 citations

Increased expression of Ia antigens on resting B cells: an additional role for B-cell growth factor.

1984 • 438 citations

Antigen-like effects of monoclonal antibodies directed at receptors on human T cell clones.

1983 • 435 citations

Sequence and expression of transcripts of the human T-cell receptor β- chain genes

1984 • 380 citations

Genomic organization and sequence of T-cell receptor β-chain constant- and joining-region genes

1984 • 377 citations

TCGF (IL 2)-receptor inducing factor(s). I. Regulation of IL 2 receptor on a natural killer-like cell line (YT cells).

1985 • 373 citations

The human t cell antigen receptor is encoded by variable, diversity, and joining gene segments that rearrange to generate a complete V gene

1984 • 306 citations

Interleukin-induced increase in Ia expression by normal mouse B cells.

1984 • 293 citations

The structure, rearrangement and expression of Dβ gene segments of the murine T-cell antigen receptor

1984 • 290 citations

Activation of cytolytic T lymphocyte and natural killer cell function through the T11 sheep erythrocyte binding protein

1985 • 287 citations

A human T lymphocyte differentiation marker defined by monoclonal antibodies that block E-rosette formation.

1981 • 281 citations

Human leukocytic pyrogen: purification and development of a radioimmunoassay.

1977 • 269 citations

The human T cell receptor: Appearance in ontogeny and biochemical relationship of α and β subunits on IL-2 dependent clones and T cell tumors

1983 • 264 citations

Purification to apparent homogeneity of murine interleukin 1.

1981 • 257 citations

Isolation of cDNA clones encoding the 20K T3 glycoprotein of human T-cell receptor complex

1984 • 232 citations

The major histocompatibility complex-restricted antigen receptor on T cells in mouse and man: Identification of constant and variable peptides

1983 • 209 citations

Production and characterization of monoclonal antibodies to human interleukin 2: strategy and tactics.

1983 • 203 citations

The events of primary T cell activation can be staged by use of Sepharose-bound anti-T3 (64.1) monoclonal antibody and purified interleukin 1.

1985 • 189 citations

Calcium dependency of antigen-specific (T3-Ti) and alternative (T11) pathways of human T-cell activation.

1984 • 175 citations

Activation of human thymocytes via the 50KD T11 sheep erythrocyte binding protein induces the expression of interleukin 2 receptors on both T3+ and T3- populations.

1985 • 170 citations

Identification of the Receptor for Antigen and Major Histocompatibility Complex on Human Inducer T Lymphocytes

1983 • 165 citations

Analysis of T-Cell Receptor Gene Rearrangement and Expression in Human Natural Killer Clones

1985 • 157 citations

The Numerous Postulated Biological Manifestations of Interleukin-1

1984 • 136 citations

Comparison of T3-associated 49- and 43-kilodalton cell surface molecules on individual human T-cell clones: evidence for peptide variability in T-cell receptor structures.

1983 • 133 citations

Lymphocyte Mitogenic Factor in Man

1969 • 117 citations

Human T Cell Antigen Expression by Primate T Cells

1982 • 115 citations

The δ- and ε-chains of the human T3/T-cell receptor complex are distinct polypeptides

1984 • 113 citations

T lymphocyte surface antigens in primates

1983 • 108 citations

Human interleukin 1. Purification to homogeneity.

1985 • 107 citations

Characterization of the two heavy chains of the T3 complex on the surface of human T lymphocytes.

1984 • 107 citations

Phenomenon of human T cells rosetting with sheep erythrocytes analyzed with monoclonal antibodies. "Modulation" of a partially hidden epitope determining the conditions of interaction between T cells and erythrocytes

1982 • 104 citations

Peptide variability exists within alpha and beta subunits of the T cell receptor for antigen.

1983 • 101 citations

Purification and NH2-terminal amino acid sequencing of the beta subunit of a human T-cell antigen receptor.

1984 • 99 citations

The T11 glycoprotein is functionally linked to a calcium channel in precursor and mature T-lineage cells.

1986 • 98 citations

Delineation of an immunoregulatory amplifier population recognizing autologous Ia molecules. Analysis with human T cell clones.

1984 • 90 citations

Subpopulations of the T4+ inducer T cell subset in man: evidence for an amplifier population preferentially expressing Ia antigen upon activation.

1981 • 86 citations

TCGF(IL 2)-receptor inducing factor(s). II. Possible role of ATL-derived factor (ADF) on constitutive IL 2 receptor expression of HTLV-I(+) T cell lines.

1985 • 84 citations

Immunoglobulin-like nature of the α-chain of a human T-cell antigen/MHC receptor

1984 • 83 citations

Antigen‐specific stimulation and trans‐stimulation of T cells in long‐term culture

1979 • 76 citations

Potentiation of in vitro Lymphocyte Reactivity

1970 • 73 citations

Purification and partial biochemical characterization of normal human interleukin 1.

1984 • 68 citations

Regulation of the alternative pathway of T cell activation by anti-T3 monoclonal antibody

1986 • 55 citations

T cell-derived B cell growth factor(s) can induce stimulation of both resting and activated B cells.

1985 • 53 citations

T3-Ti receptor triggering of T8+ suppressor T cells leads to unresponsiveness to interleukin-2

1984 • 50 citations

Antigen-specific helper T-cell clone supernatant is sufficient to induce both polyclonal proliferation and differentiation of small resting B lymphocytes.

1984 • 48 citations

Homology of Ti α-subunit of a T-cell antigen–MHC receptor with immunoglobulin

1984 • 46 citations

Helper activity of T cells stimulated in long‐term culture

1979 • 41 citations

Regulation of the alternative pathway of T cell activation by anti-T3 monoclonal antibody.

1986 • 38 citations

Multiple class I and class II major histocompatibility complex allospecificities are generated with T cell receptor variable (V) domains created by a single Ti beta V gene family.

1985 • 19 citations

Clonal analysis of B cell growth and differentiation activities induced from T lymphocytes upon triggering of T3-Ti and T11 pathways.

1985 • 15 citations

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Identification of a T Helper Cell-Derived Lymphokine That Activates Resting T Lymphocytes (1986) – Science | Metascience Observatory Explorer