TGFβ—a role in systemic sclerosis?

Stimulation of the chemotactic migration of human fibroblasts by transforming growth factor beta.

1987 • 791 citations

Transforming growth factor β (TGFβ) causes a persistent increase in steady-state amounts of type I and type III collagen and fibronectin mRNAs in normal human dermal fibroblasts

1987 • 579 citations

Latent transforming growth factor-beta 1 associates to fibroblast extracellular matrix via latent TGF-beta binding protein

1994 • 450 citations

TGF-β inhibition of endothelial cell proliferation: Alteration of EGF binding and EGF-induced growth-regulatory (competence) gene expression

1987 • 344 citations

Endothelial injury in scleroderma.

1979 • 289 citations

Scleroderma

1979 • 241 citations

Selective upregulation of platelet-derived growth factor alpha receptors by transforming growth factor beta in scleroderma fibroblasts.

1992 • 181 citations

Transcription and Expression of Transforming Growth Factor Type Beta in the Skin of Progressive Systemic Sclerosis: A Mediator of Fibrosis?

1990 • 177 citations

Immunocytochemical Localization and Serologic Detection of Transforming Growth Factor β1

1994 • 158 citations

The subnuclear localization of tRNA ligase in yeast.

1987 • 133 citations

Elevated Levels of Circulating Platelet Aggregates and Beta-Thromboglobulin in Scleroderma

1982 • 123 citations

Von Willebrand factor, thrombomodulin, thromboxane, beta-thromboglobulin and markers of fibrinolysis in primary Raynaud's phenomenon and systemic sclerosis.

1996 • 121 citations

Tissue Inhibitor of Metalloproteinase 1 (TIMP-1) May Be an Autocrine Growth Factor in Scleroderma Fibroblasts.

1997 • 99 citations

A Cytochemical Study on the Pancreas of the Guinea Pig

1959 • 78 citations

Connective tissue synthesis by cultured scleroderma fibroblasts. I. In vitro collagen synthesis by normal and scleroderma dermal fibroblasts

1976 • 75 citations

Immunohistological Demonstration of Transforming Growth Factor-β Isoforms in the Skin of Patients with Systemic Sclerosis

1993 • 59 citations

Immunohistochemical Localization of Intracellular and Extracellular Associated TGFβ in the Skin of Patients with Systemic Sclerosis (Scleroderma) and Primary Raynaud's Phenomenon

1993 • 55 citations

Basic fibroblast growth factor inhibits basal and transforming growth factor-beta induced collagen alpha 2(I) gene expression in scleroderma and normal fibroblasts.

1997 • 44 citations

Plasma TGF beta in systemic sclerosis: a cross-sectional study.

1994 • 40 citations

Increased Adhesion of Fibroblasts from Patients with Scleroderma to Extracellular Matrix Components: In Vitro Modulation by IFN-γ but Not by TGF-β

1992 • 25 citations

Deleted Work

1955 • 0 citations