Cell biology of neuronal endocytosis

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

1987 • 4,544 citations

ACIDIFICATION OF THE ENDOCYTIC AND EXOCYTIC PATHWAYS

1986 • 1,977 citations

The Biogenesis of Lysosomes

1989 • 1,583 citations

The small GTPase rab5 functions as a regulatory factor in the early endocytic pathway

1992 • 1,342 citations

Localization of low molecular weight GTP binding proteins to exocytic and endocytic compartments

1990 • 1,150 citations

Morphogenesis of the Polarized Epithelial Cell Phenotype

1989 • 1,087 citations

Targeting of cell-surface β-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments

1992 • 883 citations

The mannose 6-phosphate receptor and the biogenesis of lysosomes

1988 • 846 citations

Intracellular site of asialoglycoprotein receptor-ligand uncoupling: Double-label immunoelectron microscopy during receptor-mediated endocytosis

1983 • 816 citations

Dynamin-like protein encoded by the Drosophila shibire gene associated with vesicular traffic

1991 • 757 citations

Processing of the Amyloid Protein Precursor to Potentially Amyloidogenic Derivatives

1992 • 737 citations

Precursor of amyloid protein in Alzheimer disease undergoes fast anterograde axonal transport.

1990 • 735 citations

A unifying hypothesis for the cause of amyotrophic lateral sclerosis, parkinsonism, and alzheimer disease

1981 • 698 citations

Characterization of the early endosome and putative endocytic carrier vesicles in vivo and with an assay of vesicle fusion in vitro.

1989 • 588 citations

Multiple forms of dynamin are encoded by shibire, a Drosophila gene involved in endocytosis

1991 • 543 citations

Do GTPases direct membrane traffic in secretion?

1988 • 540 citations

rab3 is a small GTP-binding protein exclusively localized to synaptic vesicles.

1990 • 486 citations

Alzheimer amyloid protein precursor complexes with brain GTP-binding protein Go

1993 • 430 citations

Movement of internalized ligand–receptor complexes along a continuous endosomal reticulum

1990 • 428 citations

Changes in lysosome shape and distribution correlated with changes in cytoplasmic pH.

1989 • 387 citations

Two distinct subpopulations of endosomes involved in membrane recycling and transport to lysosomes

1988 • 377 citations

Advances in cellular neurobiology, 2

1982 • 376 citations

Actin-dependent organelle movement in squid axoplasm

1992 • 370 citations

The movement of membranous organelles in axons. Electron microscopic identification of anterogradely and retrogradely transported organelles.

1980 • 349 citations

Clathrin-coated vesicles in nervous tissue are involved primarily in synaptic vesicle recycling.

1992 • 321 citations

Microtubule- and motor-dependent fusion in vitro between apical and basolateral endocytic vesicles from MDCK cells

1990 • 299 citations

Colocalization of synaptophysin with transferrin receptors: implications for synaptic vesicle biogenesis.

1991 • 293 citations

The small GTP-binding protein rab4 is associated with early endosomes.

1991 • 286 citations

Alzheimer's disease: a cell biological perspective

1992 • 274 citations

Axonal and dendritic endocytic pathways in cultured neurons.

1992 • 271 citations

Endocytosis in filter-grown Madin-Darby canine kidney cells.

1989 • 264 citations

Brain dynein (MAP1C) localizes on both anterogradely and retrogradely transported membranous organelles in vivo.

1990 • 261 citations

Selective retrograde transsynaptic transfer of a protein, tetanus toxin, subsequent to its retrograde axonal transport

1979 • 229 citations

Meeting of the apical and basolateral endocytic pathways of the Madin-Darby canine kidney cell in late endosomes.

1989 • 226 citations

Synaptic vesicle membrane proteins interact to form a multimeric complex.

1992 • 219 citations

Endocytosis and signals for internalization

1991 • 209 citations

Tubular early endosomal networks in AtT20 and other cells.

1991 • 208 citations

Role of heterotrimeric G proteins in membrane traffic.

1992 • 206 citations

Internalization of lectins in neuronal GERL.

1977 • 192 citations

Regulation of apical transport in epithelial cells by a Gsclass of heterotrimeric G protein

1993 • 188 citations

Endocytosis: what goes in and how?

1992 • 177 citations

Transferrin receptor polarity and recycling accuracy in "tight" and "leaky" strains of Madin-Darby canine kidney cells.

1986 • 174 citations

Maturation models for endosome and lysosome biogenesis

1991 • 172 citations

Endocytic pathways in polarized Caco-2 cells: identification of an endosomal compartment accessible from both apical and basolateral surfaces.

1990 • 169 citations

Small GTP-binding proteins and their role in transport

1991 • 164 citations

Distribution of newly synthesized lysosomal enzymes in the endocytic pathway of normal rat kidney cells.

1991 • 164 citations

NGF receptor-mediated reduction in axonal NGF uptake and retrograde transport following sciatic nerve injury and during regeneration

1991 • 161 citations

The arguments for pre-existing early and late endosomes

1991 • 156 citations

A functional barrier to movement of lipids in polarized neurons

1992 • 147 citations

Lysosomes

1989 • 147 citations

The basis of polarity in neurons

1989 • 146 citations

Rab17, a novel small GTPase, is specific for epithelial cells and is induced during cell polarization.

1993 • 142 citations

Microtubule-associated proteins and neuronal morphogenesis

1991 • 136 citations

Basic fibroblast growth factor: receptor-mediated internalization, metabolism, and anterograde axonal transport in retinal ganglion cells

1990 • 129 citations

Synaptophysin is sorted from endocytotic markers in neuroendocrine PC12 cells but not transfected fibroblasts

1991 • 121 citations

Selective binding, uptake, and retrograde transport of tetanus toxin by nerve terminals in the rat iris. An electron microscope study using colloidal gold as a tracer

1978 • 118 citations

pH-induced microtubule-dependent redistribution of late endosomes in neuronal and epithelial cells.

1991 • 115 citations

Synaptic transmission reversibly conditioned by single-gene mutation in Drosophila melanogaster

1976 • 108 citations

The Mechanism of Action of Nerve Growth Factor

1991 • 102 citations

Endocytosis and transcytosis

1990 • 93 citations

Transport of influenza HA from the trans-Golgi network to the apical surface of MDCK cells permeabilized in their basolateral plasma membranes: energy dependence and involvement of GTP-binding proteins.

1990 • 88 citations

Phosphorylation of the cation-independent mannose 6-phosphate receptor is closely associated with its exit from the trans-Golgi network.

1993 • 85 citations

Chinese hamster ovary cell lysosomes rapidly exchange contents.

1987 • 77 citations

Membranous intermediates in endocytosis are labile, as shown in a temperature-sensitive mutant.

1989 • 74 citations

Convergence of apical and basolateral endocytic pathways at apical late endosomes in absorptive cells of suckling rat ileum in vivo

1990 • 57 citations

Lysosomal activity at nodes of Ranvier during retrograde axonal transport of horseradish peroxidase in alpha-motor neurons of the cat

1990 • 46 citations

Insulin-like growth factor-II/mannose 6-phosphate receptor is incapable of activating GTP-binding proteins in response to mannose 6-phosphate, but capable in response to insulin-like growth factor-II

1990 • 39 citations

A phosphatase activity and a synaptic vesicle antigen in multivesicular bodies of frog retinal photoreceptor terminals

1987 • 31 citations

Endocytosis of the synaptic vesicle protein, synaptophysin, requires the COOH-terminal tail.

1991 • 28 citations

Endosomes and lysosomes : a dynamic relationship

1993 • 25 citations

Properties of acidified compartments in hippocampal neurons.

1993 • 13 citations