Neuropharmacology of S-adenosyl-L-methionine

S-ADENOSYLMETHIONINE; A NEW INTERMEDIATE FORMED ENZYMATICALLY FROM l-METHIONINE AND ADENOSINETRIPHOSPHATE

1953 • 552 citations

beta-Adrenergic receptor agonists increase phospholipid methylation, membrane fluidity, and beta-adrenergic receptor-adenylate cyclase coupling.

1979 • 308 citations

The Biochemistry of Adenosylmethionine

1978 • 257 citations

Inhibition of Transmethylations of Biogenic Amines by S-Adenosylhomocysteine

1971 • 239 citations

Identification and Properties of Methyltransferases That Synthesize Phosphatidylcholine in Rat Brain Synaptosomes

1980 • 212 citations

Treatment Development Strategies for Alzheimer’s Disease

1987 • 198 citations

Phospholipid Methylation Unmasks Cryptic β-Adrenergic Receptors in Rat Reticulocytes

1979 • 179 citations

Tissue distribution of S-adenosylmethionine and S-adenosylhomocysteine in the rat. Effect of age, sex and methionine administration on the metabolism of S-adenosylmethionine, S-adenosylhomocysteine and polyamines

1977 • 149 citations

Toxicities of methionine and other amino acids

1974 • 148 citations

S‐ADENOSYLMETHIONINE IN BRAIN AND OTHER TISSUES

1966 • 143 citations

Chemotherapy in psychiatry : principles and practice

1985 • 135 citations

Age-related modification of dopaminergic and β-adrenergic receptor system: Restoration to normal activity by modifying membrane fluidity with s-adenosylmethionine

1984 • 132 citations

Biological Methylation and Drug Design

1986 • 130 citations

Transmethylation, transsulfuration, and aminopropylation reactions of S-adenosyl-L-methionine in vivo.

1984 • 129 citations

Chemotherapy in Psychiatry: Principles and Practice

1986 • 125 citations

Biological methylation and drug design

1987 • 115 citations

Effect of S-Adenosyl-L-Methionine (SAMe) upon depressive symptoms

1976 • 113 citations

Pathogenesis of methionine-induced toxicity

1970 • 111 citations

Effects of L-Dopa on Norepinephrine Metabolism in the Brain

1971 • 97 citations

Pharmacologic aspects of S-adenosylmethionine

1987 • 97 citations

The Modulation of Protein Phosphorylation and Receptor Binding in Synaptic Membranes by Changes in Lipid Fluidity: Implications for Ageing

1982 • 94 citations

Open trial of S-adenosylmethionine for treatment of depression

1984 • 84 citations

Treatment development strategies for Alzheimer's disease

1986 • 84 citations

Alterations in tissue levels of S-adenosylmethionine

1966 • 80 citations

The Regional Concentrations of S‐Adenosyl‐<scp>l</scp>‐Methionine, S‐Adenosyl‐<scp>l</scp>‐Homocysteine, and Adenosine in Rat Brain

1982 • 79 citations

Folic acid,S-adenosylmethionine and affective disorder

1983 • 77 citations

Methionine Effects on Chronic Schizophrenics

1965 • 69 citations

S-Adenosylmethionine in the treatment of osteoarthritis

1987 • 68 citations

Tissue Levels of S-adenosylmethionine in Aging Rats

1977 • 63 citations

Italian double-blind multicenter study comparing S-adenosylmethionine, naproxen, and placebo in the treatment of degenerative joint disease

1987 • 63 citations

Aging and the biophysical properties of cell membranes

1985 • 61 citations

Typical and atypical antidepressants. Clinical practice.

1982 • 56 citations

Effect of S-adenosyl-L-methionine on serotonin metabolism in rat brain

1978 • 56 citations

Typical and Atypical Antidepressants. Clinical Practice

1983 • 50 citations

Double-blind multicentre study of the activity of S-adenosylmethionine in hip and knee osteoarthritis.

1985 • 48 citations

Intestinal absorption of S-adenosyl-L-methionine.

1979 • 45 citations

Decreased in vivo protein and phospholipid methylation after in vivo elevation of brain S-adenosyl-homocysteine

1981 • 45 citations

Affective Illness and S-Adenosyl Methionine

1986 • 44 citations

Phospholipid Methylation Increases [³H]Diazepam and [³H]GABA Binding in Membrane Preparations of Rat Cerebellum

1983 • 43 citations

Abnormalities of one-carbon metabolism in psychiatric disorders: Study of methionine adenosyltransferase kinetics and lipid composition of erythrocyte membranes

1986 • 36 citations

Pharmacokinetics of S-adenosyl-L-methionine in healthy volunteers

1984 • 32 citations

Biological Transmethylation Involving S-Adenosylmethionine: Development of Assay Methods and Implications for Neuropsychiatry

1975 • 31 citations

Depletion of S-adenosyl-L-methionine in mouse brain by antidepressive drugs.

1975 • 30 citations

Comparison between the antidepressant activity and of S-adenosylmethionine (SAMe) and that of some tricyclic drugs.

1978 • 29 citations

Inhibition of Rat Brain Microsomal Na⁺,K⁺‐ATPase by S‐Adenosylmethionine

1984 • 27 citations

Methylation Hypothesis

1979 • 26 citations

[Therapeutic effects and mechanism of action of S-adenosyl-L-methionine (SAM) in depressive syndromes].

1973 • 25 citations

S-Adenosyl-L-methionine in the Treatment of Alzheimer??s Disease

1988 • 25 citations

The effect of S-adenosyl-l-methionine on ischemia-induced disturbances of brain phospholipid in the gerbil

1983 • 24 citations

A new medical approach to the treatment of osteoarthritis

1987 • 23 citations

Phospholipid Methylation and Noradrenaline Exchanges in a Synaptosomal Preparation from the Rat Brain

1982 • 22 citations

Early clinical double-blind study with S-adenosyl-L-methionine: a new potential antidepressant.

1982 • 20 citations

Transmethylations and the Central Nervous System

1978 • 19 citations

[Controlled double-blind study (SAMe-imipramine) in depressive syndromes].

1975 • 17 citations

Blood S-adenosyl-L-methionine levels in psychiatric disorders

1982 • 16 citations

S-adenosylmethionine excites rat cerebral cortical neurons

1981 • 14 citations

S-adenosyl-L-methionine modulates phosphatidylethanolamine me methyltransferase response to isoproterenol in brain

1986 • 12 citations

A Biochemical Study of Depressed Patients Receiving S-Adenosyl-L-Methionine (SAM)

1986 • 12 citations

Decreased cerebral catabolism of [3H]histamine in vivo after S-adenosylmethionine administration.

1981 • 12 citations

Effects of S-adenosyl-methionine on plasma norepinephrine, blood pressure, and heart rate in healthy volunteers

1986 • 12 citations

Proceedings of the 14th Collegium Internationale Neuro-Psychopharmacologicum Congress

1984 • 11 citations

S-Adenosylmethionine in human blood

1971 • 10 citations

The increase in S-adenosyl-L-methionine (SAMe) concentration in rat brain after its systemic administration.

1977 • 10 citations

Incorporation of Intracisternally Administered <scp>l</scp>‐[methyl‐³H]Methionine and S‐Adenosyl‐<scp>l</scp>‐[methyl‐³H]‐Methionine into Rat Brain Phospholipids

1985 • 10 citations

A subacute treatment of L-methionine induces an increase in the number of [3H]spiperone binding sites in the striatum of the rat

1983 • 8 citations

Concentrations of S-Adenosyl-L-Methionine in the CNS of Rats After Intramuscular and Intravenous Administration

1978 • 7 citations

Effets de la S-adénosylméthionine et de la s-adénosylhomocystéine sur la synthése, in vivo, de la noradrénaline et de la sérotonine dans différentes parties du cerveau de rat.

1979 • 2 citations

Deleted Work

1955 • 0 citations