The CD14+ CD16+ blood monocytes: their role in infection and inflammation

Blood Monocytes Consist of Two Principal Subsets with Distinct Migratory Properties

2003 • 3,265 citations

Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2

2006 • 1,544 citations

Heme oxygenase-1: unleashing the protective properties of heme

2003 • 1,137 citations

Subpopulations of Mouse Blood Monocytes Differ in Maturation Stage and Inflammatory Response

2004 • 1,094 citations

Identification and characterization of a novel monocyte subpopulation in human peripheral blood

1989 • 941 citations

The Proinflammatory CD14+CD16+DR++ Monocytes Are a Major Source of TNF

2002 • 845 citations

Regulation of scavenger receptor CD163 expression in human monocytes and macrophages by pro- and antiinflammatory stimuli

2000 • 685 citations

Fractalkine Preferentially Mediates Arrest and Migration of CD16+ Monocytes

2003 • 563 citations

Emigration of monocyte-derived cells from atherosclerotic lesions characterizes regressive, but not progressive, plaques

2004 • 501 citations

The novel subset of CD14+/CD16+ blood monocytes is expanded in sepsis patients

1993 • 467 citations

The macrophage scavenger receptor CD163

2005 • 411 citations

TLR activation triggers the rapid differentiation of monocytes into macrophages and dendritic cells

2005 • 395 citations

Differential chemokine receptor expression and function in human monocyte subpopulations

2000 • 389 citations

The novel subset of CD14⁺/CD16⁺ blood monocytes exhibits features of tissue macrophages

1993 • 383 citations

Unique monocyte subset in patients with AIDS dementia

1997 • 371 citations

Perivascular Macrophages Are the Primary Cell Type Productively Infected by Simian Immunodeficiency Virus in the Brains of Macaques

2001 • 365 citations

The CD16+ (FcγRIII+) Subset of Human Monocytes Preferentially Becomes Migratory Dendritic Cells in a Model Tissue Setting

2002 • 360 citations

CNS invasion by CD14+/CD16+ peripheral blood-derived monocytes in HIV dementia: perivascular accumulation and reservoir of HIV infection

2001 • 354 citations

Dual Functions of Fractalkine/CX3C Ligand 1 in Trafficking of Perforin+/Granzyme B+ Cytotoxic Effector Lymphocytes That Are Defined by CX3CR1 Expression

2002 • 320 citations

CD14+,CD16+ blood monocytes and joint inflammation in rheumatoid arthritis

2002 • 317 citations

Differential cytokine expression in human blood monocyte subpopulations: a polymerase chain reaction analysis

1996 • 311 citations

Fractalkine in Vascular Biology

2003 • 306 citations

CD14^lowCD16^high: A cytokine‐producing monocyte subset which expands during human immunodeficiency virus infection

1995 • 287 citations

CD14+CD16+ monocytes in coronary artery disease and their relationship to serum TNF-α levels

2004 • 287 citations

Human peripheral blood dendritic cell subsets. Isolation and characterization of precursor and mature antigen-presenting cells.

1994 • 252 citations

Tetrameric Complexes of Human Histocompatibility Leukocyte Antigen (HLA)-G Bind to Peripheral Blood Myelomonocytic Cells

1999 • 252 citations

Expression of toll‐like receptor 2 on CD16+ blood monocytes and synovial tissue macrophages in rheumatoid arthritis

2004 • 251 citations

Monocytes harbour replication-competent, non-latent HIV-1 in patients on highly active antiretroviral therapy

2001 • 238 citations

6-Sulfo LacNAc, a Novel Carbohydrate Modification of PSGL-1, Defines an Inflammatory Type of Human Dendritic Cells

2002 • 211 citations

Detection of Infectious HIV in Circulating Monocytes From Patients on Prolonged Highly Active Antiretroviral Therapy

2000 • 197 citations

The Role of CC Chemokine Receptor 2 in Alveolar Monocyte and Neutrophil Immigration in Intact Mice

2002 • 196 citations

Peripheral Blood Mononuclear Phagocyte Subpopulations as Cellular Markers in Hypercholesterolemia

1996 • 195 citations

Selective mobilization of CD14⁺CD16⁺ monocytes by exercise

2000 • 188 citations

Expanded CD14⁺CD16⁺Monocyte Subpopulation in Patients with Acute and Chronic Infections Undergoing Hemodialysis

1998 • 185 citations

CD16. Developmentally regulated IgG Fc receptors on cultured human monocytes.

1988 • 170 citations

Generalized immune activation in pulmonary tuberculosis: co-activation with HIV infection

1996 • 170 citations

Human cartilage gp‐39+,CD16+ monocytes in peripheral blood and synovium: Correlation with joint destruction in rheumatoid arthritis

2000 • 166 citations

Inflammatory signals associated with hemodialysis

2002 • 161 citations

CD16+ and CD16− human blood monocyte subsets differentiate in vitro to dendritic cells with different abilities to stimulate CD4+ T cells

2001 • 156 citations

Monocyte-derived dendritic cells

2005 • 155 citations

Phenotypical and functional characterization of Fey receptor I (CD64)‐negative monocytes, a minor human monocyte subpopulation with high accessory and antiviral activity

1993 • 152 citations

Selective depletion of CD14+ CD16+ monocytes by glucocorticoid therapy

1998 • 150 citations

Relationships between Distinct Blood Monocyte Subsets and Migrating Intestinal Lymph Dendritic Cells In Vivo under Steady-State Conditions

2006 • 148 citations

Association of circulating receptor Fc gamma RIII-positive monocytes in AIDS patients with elevated levels of transforming growth factor-beta.

1991 • 148 citations

Identification of a novel dendritic cell-like subset of CD64(+) / CD16(+) blood monocytes.

2001 • 146 citations

Monocyte/macrophage traffic in HIV and SIV encephalitis

2003 • 129 citations

The porcine 2A10 antigen is homologous to human CD163 and related to macrophage differentiation.

1999 • 129 citations

Magnetic resonance spectroscopy reveals that activated monocytes contribute to neuronal injury in SIV neuroAIDS

2005 • 129 citations

CD14⁺CD16⁺ Monocytes in the Course of Sepsis in Neonates and Small Children: Monitoring and Functional Studies

2002 • 124 citations

Identification of a novel dendritic cell-like subset of CD64+ / CD16+ blood monocytes

2001 • 121 citations

Mechanism of glucocorticoid-induced depletion of human CD14+CD16+ monocytes

2003 • 117 citations

Increased Serum Levels of MRP-8/14 in Type 1 Diabetes Induce an Increased Expression of CD11b and an Enhanced Adhesion of Circulating Monocytes to Fibronectin

2004 • 113 citations

Regulation of Intestinal Dendritic Cell Migration and Activation by Plasmacytoid Dendritic Cells, TNF-α and Type 1 IFNs after Feeding a TLR7/8 Ligand

2006 • 112 citations

The Porcine 2A10 Antigen Is Homologous to Human CD163 and Related to Macrophage Differentiation

1999 • 110 citations

The Monoclonal Antimonocyte Antibody My4 Stains B Lymphocytes and Two Distinct Monocyte Subsets in Human Peripheral Blood

1988 • 109 citations

CD14+CD16+ monocyte subpopulation in Kawasaki disease

2000 • 104 citations

Macrophages, smooth muscle cells, endothelial cells, and T-cells express CD40 and CD40L in fatty streaks and more advanced human atherosclerotic lesions

2000 • 101 citations

Antitumor response of CD14+/CD16+ monocyte subpopulation

2004 • 97 citations

Expression of Fc and complement receptors on peripheral blood monocytes in systemic lupus erythematosus and rheumatoid arthritis

2004 • 96 citations

Transendothelial migration of CD16+ monocytes in response to fractalkine under constitutive and inflammatory conditions

2004 • 93 citations

Comparative Analysis of the Morphological, Cytochemical, Immunophenotypical, and Functional Characteristics of Normal Human Peripheral Blood Lineage−/CD16+/HLA-DR+/CD14−/lo Cells, CD14+ Monocytes, and CD16− Dendritic Cells

2001 • 92 citations

Impact of highly active anti-retroviral therapy (HAART) on cytokine production and monocyte subsets in HIV-infected patients

2000 • 87 citations

Increased expression of Fcγ receptors II and III on macrophages of rheumatoid arthritis patients results in higher production of tumor necrosis factor α and matrix metalloproteinase

2003 • 82 citations

Phenotypic and functional heterogeneity of porcine blood monocytes and its relation with maturation

2004 • 82 citations

CD16+ monocytes exposed to HIV promote highly efficient viral replication upon differentiation into macrophages and interaction with T cells

2005 • 77 citations

CD16+ Monocyte-Derived Macrophages Activate Resting T Cells for HIV Infection by Producing CCR3 and CCR4 Ligands

2006 • 77 citations

Strong depletion of CD14+CD16+ monocytes during haemodialysis treatment

2001 • 76 citations

Selective expansion of CD16highCCR2– subpopulation of circulating monocytes with preferential production of haem oxygenase (HO)-1 in response to acute inflammation

2005 • 74 citations

Mechanisms of Intravenous Immunoglobulin Action in Immune Thrombocytopenic Purpura

2005 • 71 citations

Circulating monocytes in patients with diabetes mellitus, arterial disease, and increased CD14 expression

2000 • 70 citations

HIV-1 DNA and mRNA concentrations are similar in peripheral blood monocytes and alveolar macrophages in HIV-1-infected individuals

1998 • 69 citations

CYTOKINE PRODUCTION PRECEDES THE EXPANSION OF CD14+CD16+ MONOCYTES IN HUMAN SEPSIS

1997 • 69 citations

The CD14+CD16+ monocytes in erysipelas are expanded and show reduced cytokine production

2002 • 69 citations

Phenotype and function of a CD56+ peripheral blood monocyte

2004 • 67 citations

Expression patterns of Fcγ receptors, HLA-DR and selected adhesion molecules on monocytes from normal and HIV-infected individuals

1994 • 66 citations

The human EGF-TM7 family member EMR2 is a heterodimeric receptor expressed on myeloid cells

2002 • 65 citations

The CD14+ CD16+ monocyte subset in rheumatoid arthritis and systemic lupus erythematosus

2002 • 64 citations

Interleukin-10 drives human monocytes to CD16 positive macrophages.

1996 • 64 citations

Increased expression of Fc receptors on neutrophils and monocytes may reflect ongoing bacterial infection

1996 • 63 citations

Fcgamma receptor expression levels on monocytes are elevated in rheumatoid arthritis patients with high erythrocyte sedimentation rate who do not use anti-rheumatic drugs

2003 • 60 citations

Preperitoneal Herniation Into a Laparoscopic Port Site Without a Fascial Defect

2002 • 60 citations

Inhibition of CX3CL1 (Fractalkine) Improves Experimental Autoimmune Myositis in SJL/J Mice

2005 • 59 citations

Monoclonal antibodies against rat macrophages

1994 • 56 citations

Circulating CD14⁺ CD16⁺ Monocytes Are Expanded in Sarcoidosis Patients

2003 • 56 citations

Expression of CD14, CD16 and CD45RA on monocytes from periodontitis patients

2003 • 55 citations

Identification of Two Subpopulations of Rat Monocytes Expressing Disparate Molecular Forms and Quantities of CD43

1995 • 54 citations

The Prevalence and Distribution of Macrophages Bearing FcγR I, FcγR II, and FcγR III in Synovium

1990 • 52 citations

Blood monocytes of untreated asthmatics exhibit some features of tissue macrophages

1995 • 52 citations

Recombinant human macrophage colony-stimulating factor in nonhuman primates: selective expansion of a CD16+ monocyte subset with phenotypic similarity to primate natural killer cells

1996 • 48 citations

Transforming growth factor-beta in synovial fluids modulates Fc gamma RII (CD16) expression on mononuclear phagocytes.

1992 • 47 citations

Rat monocytes up-regulate NKR-P1A and down-modulate CD4 and CD43 during activation in vivo: monocyte subpopulations in normal and IFN-γ-treated rats

1997 • 46 citations

Characterization of monocyte subtypes in the allergic form of atopic eczema/dermatitis syndrome

2002 • 39 citations

Diabetes-prone NOD mice show an expanded subpopulation of mature circulating monocytes, which preferentially develop into macrophage-like cells in vitro

2005 • 39 citations

The M-DC8-positive Leukocytes are a Subpopulation of the CD14+CD16+Monocytes

2000 • 39 citations

CD14dim/CD16bright monocytes in hemophagocytic lymphohistiocytosis

2001 • 39 citations

Soluble CD14 receptor expression and monocyte heterogeneity but not the C-260T CD14 genotype are associated with severe acute pancreatitis

2004 • 38 citations

Differential expression of function-related antigens on blood monocytes in children with hemolytic uremic syndrome

2005 • 38 citations

Haemodialysis monocytopenia: differential sequestration kinetics of CD14+CD16+ and CD14++ blood monocyte subsets

2001 • 36 citations

Monocytes in the Rat

2000 • 35 citations

Potential role of heme oxygenase-1 in the progression of rat adjuvant arthritis

2004 • 34 citations

The Antibody MY4 Recognizes CD14 on Porcine Monocytes and Macrophages

1994 • 33 citations

Short Communication: Phenotypic Changes in Peripheral Blood Monocytes of Cynomolgus Monkeys Acutely Infected with Simian Immunodeficiency Virus

1998 • 32 citations

Difference in the blood monocyte phenotype between uremic patients and healthy controls: its relation to monocyte differentiation into macrophages in the peritoneal cavity.

1998 • 31 citations

Peripheral blood monocyte activation during coronary artery bypass grafting with or without cardiopulmonary bypass

2005 • 31 citations

Adrenaline-induced immunological changes are altered in patients with rheumatoid arthritis

2002 • 30 citations

Expansion of CD14+CD16+ Blood Monocytes in Patients with Chronic Renal Failure Undergoing Dialysis: Possible Involvement of Macrophage Colony-Stimulating Factor

2001 • 29 citations

CD16+ human monocyte-derived dendritic cells matured with different and unrelated stimuli promote similar allogeneic Th2 responses: regulation by pro- and anti-inflammatory cytokines

2004 • 29 citations

Expression of Fc Gamma Receptor III (CD16) on Monocytes during Hemodialysis in Patients with Chronic Renal Failure

2001 • 21 citations

Regulation of the expression of Fcγ receptor on circulating neutrophils and monocytes in Kawasaki disease

1999 • 20 citations

Enrichment of activated monocytes in cerebrospinal fluid during antiretroviral therapy

2005 • 17 citations

Impact of Different Immunosuppressive Regimens on Antigen-Presenting Blood Cells in Kidney Transplant Patients

2004 • 17 citations

Increased circulating CD16+ CD14dim monocytes in a patient with pulmonary alveolar proteinosis

2002 • 13 citations

Monocyte Fc gamma receptor expression in patients undergoing coronary artery bypass grafting

2004 • 13 citations