Current chemotherapeutic treatment of malignant pleural mesothelioma

Resection margins, extrapleural nodal status, and cell type determine postoperative long-term survival in trimodality therapy of malignant pleural mesothelioma: Results in 183 patients

1999 • 985 citations

Modified RECIST criteria for assessment of response in malignant pleural mesothelioma

2004 • 614 citations

Continuing increase in mesothelioma mortality in Britain

1995 • 573 citations

LY231514, a pyrrolo[2,3-d]pyrimidine-based antifolate that inhibits multiple folate-requiring enzymes.

1997 • 560 citations

Prognostic factors in patients with pleural mesothelioma: the European Organization for Research and Treatment of Cancer experience.

1998 • 537 citations

Mesothelin-family proteins and diagnosis of mesothelioma

2003 • 533 citations

Prevention of Malignant Seeding After Invasive Diagnostic Procedures in Patients With Pleural Mesothelioma

1995 • 459 citations

Gemcitabine: preclinical pharmacology and mechanisms of action.

1996 • 401 citations

The pathogenesis of mesothelioma

2002 • 389 citations

Phase III Trial Comparing a Defined Duration of Therapy Versus Continuous Therapy Followed by Second-Line Therapy in Advanced-Stage IIIB/IV Non-Small-Cell Lung Cancer

2002 • 370 citations

Cisplatin and Gemcitabine Treatment for Malignant Mesothelioma: A Phase II Study

1999 • 336 citations

Patterns of Failure After Trimodality Therapy for Malignant Pleural Mesothelioma

1997 • 305 citations

Pathology of malignant mesothelioma

1997 • 283 citations

Analysis of Current Trends in United States Mesothelioma Incidence

1997 • 279 citations

Phase II Study of Pemetrexed With and Without Folic Acid and Vitamin B₁₂ as Front-Line Therapy in Malignant Pleural Mesothelioma

2003 • 260 citations

Metabolic Imaging of Malignant Pleural Mesothelioma With Fluorodeoxyglucose Positron Emission Tomography

1998 • 252 citations

Neoadjuvant Chemotherapy Followed by Extrapleural Pneumonectomy in Malignant Pleural Mesothelioma

2004 • 244 citations

Chemotherapy in malignant pleural mesothelioma. A review.

1996 • 229 citations

A multicentre phase II study of cisplatin and gemcitabine for malignant mesothelioma

2002 • 225 citations

Phase II Study of Vinorelbine in Patients With Malignant Pleural Mesothelioma

2000 • 201 citations

Comparison of insufflated talc under thoracoscopic guidance with standard tetracycline and bleomycin pleurodesis for control of malignant pleural effusions

1993 • 175 citations

Preclinical, pharmacologic, and phase I studies of gemcitabine.

1997 • 173 citations

Multicentre phase II study of gemcitabine and cisplatin in malignant pleural mesothelioma

2002 • 157 citations

Clinical and Pharmacokinetic Phase I Study of Multitargeted Antifolate (LY231514) in Combination With Cisplatin

1999 • 155 citations

The α folate receptor is highly activated in malignant pleural mesothelioma

2001 • 151 citations

Phase I Clinical and Pharmacokinetic Study of Pemetrexed and Carboplatin in Patients With Malignant Pleural Mesothelioma

2002 • 149 citations

High-dose methotrexate in the treatment of malignant mesothelioma of the pleura. A phase II study

1992 • 147 citations

Advances in the Treatment of Malignant Pleural Mesothelioma

1999 • 143 citations

Malignant mesothelioma in Australia, 1945–2000*

2002 • 138 citations

Statement on malignant mesothelioma in the United Kingdom

2001 • 137 citations

Combination of Raltitrexed and Oxaliplatin Is an Active Regimen in Malignant Mesothelioma: Results of a Phase II Study

2003 • 134 citations

A phase II study of gemcitabine in patients with malignant pleural mesothelioma

1999 • 130 citations

Positron emission tomography with f18-fluorodeoxyglucose in the staging and preoperative evaluation of malignant pleural mesothelioma

2000 • 130 citations

Malignant mesothelioma. The eastern cooperative oncology group (ECOG) experience

1983 • 128 citations

Gemcitabine combined with carboplatin in patients with malignant pleural mesothelioma

2003 • 116 citations

Surgical Treatment of Malignant Pleural Mesothelioma*

2003 • 111 citations

Assessing Quality of Life During Chemotherapy for Pleural Mesothelioma: Feasibility, Validity, and Results of Using the European Organization for Research and Treatment of Cancer Core Quality of Life Questionnaire and Lung Cancer Module

2004 • 110 citations

Capecitabine in malignant mesothelioma: a phase II trial by the Cancer and Leukemia Group B (39807)

2003 • 107 citations

Pleural mesothelioma: little evidence, still time to do trials

2004 • 105 citations

Gemcitabine for malignant mesothelioma: A phase II trial by the Cancer and Leukemia Group B

2001 • 101 citations

Trimetrexate in malignant mesothelioma: A Cancer and Leukemia Group B Phase II study.

1994 • 82 citations

Talc Induces Apoptosis in Human Malignant Mesothelioma Cells In Vitro

2000 • 81 citations

Activity of doxorubicin and cisplatin combination chemotherapy in patients with diffuse malignant pleural mesothelioma. An italian lung cancer task force (FONICAP) phase II study

1991 • 79 citations

A phase II study of gemcitabine in patients with malignant pleural mesothelioma

1999 • 79 citations

Cisplatin and Gemcitabine in Malignant Pleural Mesothelioma: A Phase II Study

2005 • 69 citations

An overview of folate metabolism: features relevant to the action and toxicities of antifolate anticancer agents.

1999 • 66 citations

Edatrexate (10-ethyl-deaza-aminopterin) (NSC #626715) with or without leucovorin rescue for malignant mesothelioma. Sequential phase II trials by the cancer and leukemia group B.

1999 • 66 citations

Epirubicin in malignant mesothelioma: a phase II study of the European Organization for Research and Treatment of Cancer Lung Cancer Cooperative Group.

1992 • 62 citations

Pemetrexed: A multitargeted antifolate agent with promising activity in solid tumors

2000 • 60 citations

A prospective study of detorubicin in malignant mesothelioma

1985 • 54 citations

Pleuroperitoneal shunt for recurrent malignant pleural effusions.

1990 • 51 citations

INTERPLEURAL ANALGESIA

1993 • 41 citations

The immune anti-tumor effects of GM-CSF and B7-1 gene transfection are enhanced by surgical debulking of tumor

2001 • 39 citations

Contemporary Management of Malignant Pleural Mesothelioma

1999 • 39 citations

A phase II study of pirarubicin in malignant pleural mesothelioma

1990 • 38 citations

Role of¹⁸F-FDG PET for Evaluating Malignant Pleural Mesothelioma

2004 • 33 citations

A novel folate transport activity in human mesothelioma cell lines with high affinity and specificity for the new-generation antifolate, pemetrexed.

2002 • 31 citations

A randomized phase III study of cisplatin with or without raltitrexed in patients (pts) with malignant pleural mesothelioma (MPM): an intergroup study of the EORTC Lung Cancer Group and NCIC

2004 • 29 citations

Conventional Treatment and its Effect on Survival of Malignant Pleural Mesothelioma in Western Australia

1982 • 26 citations

Indications and limitations of radiotherapy in malignant pleural mesothelioma

2003 • 24 citations

Multimodal treatment for resectable epithelial type malignant pleural mesothelioma.

2004 • 20 citations

Estimating the Induction Period of Pleural Mesothelioma From Aggregate Data on Asbestos Consumption

2003 • 17 citations

A phase 2 clinical trial of pemetrexed plus gemcitabine as front-line chemotherapy for patients with malignant pleural mesothelioma (MPM)

2004 • 9 citations

Pemetrexed in combination with cisplatin in the treatment of chemonaive patients with malignant pleural mesothelioma (MPM): Outcomes on Expanded Access Program (EAP)

2004 • 5 citations

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