CAPTOPRIL IN THE TREATMENT OF CLINICAL HYPERTENSION AND CARDIAC FAILURE

Design of Specific Inhibitors of Angiotensin-Converting Enzyme: New Class of Orally Active Antihypertensive Agents

1977 • 1,851 citations

Antihypertensive Effect of the Oral Angiotensin Converting-Enzyme Inhibitor SQ 14225 in Man

1978 • 612 citations

Angiotensin I converting enzyme.

1975 • 566 citations

Role of the renin-angiotensin system in the systemic vasoconstriction of chronic congestive heart failure.

1978 • 396 citations

Clinical experience with blockade of the renin-angiotensin-aldosterone system by an oral converting-enzyme inhibitor (SQ 14,225, captopril) in hypertensive patients

1978 • 364 citations

Oral Angiotensin-Converting Enzyme Inhibitor in Long-Term Treatment of Hypertensive Patients

1979 • 357 citations

Reciprocal Influence of Salt Intake on Adrenal Glomerulosa and Renal Vascular Responses to Angiotensin II in Normal Man

1974 • 333 citations

A SPECIFIC ORALLY ACTIVE INHIBITOR OF ANGIOTENSIN-CONVERTING ENZYME IN MAN

1977 • 332 citations

Angiotensin converting enzyme inhibition in patients with congestive heart failure.

1978 • 238 citations

Converting enzyme inhibition with an orally active compound in hypertensive man.

1979 • 224 citations

Reversal of Vascular and Renal Crises of Scleroderma by Oral Angiotensin-Converting-Enzyme Blockade

1979 • 210 citations

SQ 14,225 (D-3-mercapto-2-methylpropanoyl-l-proline), a novel orally active inhibitor of angiotensin I-converting enzyme.

1978 • 209 citations

LONG-TERM EFFECTS OF CAPTOPRIL (SQ14 225) ON BLOOD-PRESSURE AND HORMONE LEVELS IN ESSENTIAL HYPERTENSION

1979 • 191 citations

Hypertension in chronic renal failure

1973 • 186 citations

Interruption of the renin-angiotensin system in hypertensive patients by captopril induces sustained reduction in aldosterone secretion, potassium retention and natruiresis.

1979 • 185 citations

IMPROVEMENT OF CHRONIC CONGESTIVE HEART-FAILURE BY ORAL CAPTOPRIL

1979 • 180 citations

Converting enzyme inhibition in essential hypertension: the hypotensive response does not reflect only reduced angiotensin II formation.

1979 • 177 citations

Renin relationships in congestive cardiac failure, treated and untreated

1970 • 176 citations

Sensitization of the adrenal cortex to angiotensin II in sodium-deplete man

1977 • 173 citations

Haemodynamics of Orally-Active Converting Enzyme Inhibitor (SQ 14225) in Hypertensive Patients

1978 • 147 citations

Angiotensin converting enzyme inhibition in patients with congestive heart failure.

1978 • 143 citations

Arterial Hypertension Elicited by Subpressor Amounts of Angiotensin

1965 • 140 citations

Increased Glomerular Filtration Rate after Converting-Enzyme Inhibition in Essential Hypertension

1979 • 137 citations

A SLOWLY DEVELOPING PRESSOR RESPONSE TO SMALL CONCENTRATIONS OF ANGIOTENSIN ITS BEARING ON THE PATHOGENESIS OF CHRONIC RENAL HYPERTENSION

1963 • 133 citations

HYPERTENSION AND CHRONIC RENAL FAILURE

1971 • 124 citations

Sensitization of the Adrenal Cortex to Angiotensin II in Sodium-Deplete Man

1974 • 122 citations

ABNORMAL RELATION BETWEEN EXCHANGEABLE SODIUM AND THE RENIN-ANGIOTENSIN SYSTEM IN MALIGNANT HYPERTENSION AND IN HYPERTENSION WITH CHRONIC RENAL FAILURE

1973 • 121 citations

Plasma Renin Concentration and the Control of Blood Pressure in Patients on Maintenance Haemodialysis

1969 • 119 citations

Renin and angiotensin. A survey of some aspects

1966 • 116 citations

Captopril (SQ 14,225) (d-3-mercapto-2-methylpropanoyl-l-proline): A novel orally active inhibitor of angiotensin-converting enzyme and antihypertensive agent

1978 • 114 citations

The Response of Blood Pressure to Infusion of Angiotensin II: Relation to Plasma Concentrations of Renin and Angiotensin II

1972 • 113 citations

Converting enzyme inhibitor and saralasin infusion in rats. Evidence for an additional vasodepressor property of converting enzyme inhibitor.

1978 • 103 citations

THE MECHANISM OF RENAL HYPERTENSION.

1940 • 101 citations

George C. Griffith lecture. The role of renin in normal and pathological cardiovascular homeostasis.

1976 • 97 citations

INNAPPROPRIATE RENIN SECRETION UNMASKED BY CAPTOPRIL (SQ 14 225) IN HYPERTENSION OF CHRONIC RENAL FAILURE

1978 • 86 citations

Arterial Wall or Plasma Renin in Hypertension?

1979 • 86 citations

HYPONATRÆMIC HYPERTENSIVE SYNDROME WITH RENAL-ARTERY OCCLUSION CORRECTED BY CAPTOPRIL

1979 • 72 citations

Bilateral nephrectomy for control of hypertension in uremia.

1968 • 69 citations

CORRECTION OF RENAL HYPERTENSION IN THE RAT BY PROLONGED INFUSION OF ANGIOTENSIN INHIBITORS

1977 • 67 citations

Mechanisms involved in the progressive pressor response to very small amounts of angiotensin in conscious rabbits.

1967 • 67 citations

The relation of arterial pressure and plasma angiotensin II concentration. A change produced by prolonged infusion of angiotensin II in the conscious dog.

1979 • 66 citations

Angiotensin II, aldosterone and arterial pressure: a quantitative approach. Arthur C. Corcoran Memorial Lecture.

1979 • 63 citations

Chronic antihypertensive effects of captopril (SQ 14,225), an orally active angiotensin I-converting enzyme inhibitor, in conscious 2-kidney renal hypertensive rats

1978 • 62 citations

Antihypertensive Effect of Prolonged Blockade of Angiotensin Formation in Benign and Malignant, one- and two-Kidney Goldblatt Hypertensive Rats

1979 • 60 citations

Blood pressure and plasma angiotensin II concentration after renal artery constriction and angiotensin infusion in the dog. (5-Isoleucine)angiotensin II and its breakdown fragments in dog blood.

1976 • 57 citations

Hemodialysis-Resistant Hypertension: Control with an Orally Active Inhibitor of Angiotensin-Converting Enzyme*

1979 • 49 citations

Captopril in Hypertension with Renal Artery Stenosis and in Intractable Hypertension; Acute and Chronic Changes in Circulating Concentrations of Renin, Angiotensins I and II and Aldosterone, and in Body Composition

1979 • 37 citations

Inhibitors of the renin‐angiotensin system in experimental hypertension, with a note on the measurement of angiotensin I, II and III during infusion of converting‐enzyme inhibitor.

1979 • 36 citations

Angiotensin II blockade in normal man: Interaction of renin and sodium in maintaining blood pressure

1977 • 35 citations

Mechanism of blood pressure reduction by teprotide (SQ 20881) in rats

1978 • 31 citations

Does the Renin—Angiotensin System Maintain Blood Pressure in Both Hypertensive and Normotensive Subjects? a Comparison of Propranolol, Saralasin and Captopril

1979 • 29 citations

Hormonal Changes with Long-Term Converting-Enzyme Inhibition by Captopril in Essential Hypertension

1979 • 25 citations

Angiotensin II and Renal Hypertension in Dog, Rat and Man: Effect of Converting Enzyme Inhibition

1980 • 24 citations

Book Review: Mild Hypertension: Natural History and Management

1979 • 23 citations

Efficacy of an Oral Angiotensin-Converting Enzyme Inhibitor (Captopril) in Severe Hypertension

1981 • 17 citations

Significance of renin and angiotensin in hypertension.

1978 • 11 citations

Humoral Effects of the Oral Converting-Enzyme Inhibitor Sq 14 225 in Hypertensive Patients in Supine and Tilted Position

1979 • 8 citations

EFFECT OF BETA-ADRENERGIC BLOCKADE ON PLASMA-RENIN ACTIVITY AND INTRACTABLE HYPERTENSION IN PATIENTS RECEIVING REGULAR DIALYSIS TREATMENT

1976 • 8 citations

Efficacy of an oral angiotensin-converting enzyme inhibitor (captopril) in severe hypertension

1981 • 5 citations

Long-Term Propranolol Treatment of Resistant Arterial Hypertension in Haemodialysed Patients

1974 • 5 citations

Deleted Work

1955 • 0 citations