Neurotrophin Receptor-interacting Mage Homologue Is an Inducible Inhibitor of Apoptosis Protein-interacting Protein That Augments Cell Death

High-efficiency transformation of mammalian cells by plasmid DNA.

1987 • 5,377 citations

Smac, a Mitochondrial Protein that Promotes Cytochrome c–Dependent Caspase Activation by Eliminating IAP Inhibition

2000 • 3,415 citations

A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma

1997 • 3,167 citations

IAP family proteins---suppressors of apoptosis

1999 • 2,570 citations

Identification of DIABLO, a Mammalian Protein that Promotes Apoptosis by Binding to and Antagonizing IAP Proteins

2000 • 2,344 citations

X-linked IAP is a direct inhibitor of cell-death proteases

1997 • 1,961 citations

Neurotrophin signal transduction in the nervous system

2000 • 1,910 citations

The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases

1997 • 1,316 citations

The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins

1995 • 1,237 citations

Bcl-2 family proteins

1998 • 1,055 citations

Ubiquitin Protein Ligase Activity of IAPs and Their Degradation in Proteasomes in Response to Apoptotic Stimuli

2000 • 989 citations

The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy

1995 • 976 citations

Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-κB control

1997 • 875 citations

Bcl-2 Targets the Protein Kinase Raf-1 to Mitochondria

1996 • 785 citations

A conserved family of cellular genes related to the baculovirus iap gene and encoding apoptosis inhibitors.

1996 • 637 citations

Demonstration of permanent factor-dependent multipotential (erythroid/neutrophil/basophil) hematopoietic progenitor cell lines.

1983 • 559 citations

Control of Programmed Cell Death by the Baculovirus Genes p35 and iap

1994 • 517 citations

Cloning and expression of apoptosis inhibitory protein homologs that function to inhibit apoptosis and/or bind tumor necrosis factor receptor-associated factors.

1996 • 515 citations

Identification of XAF1 as an antagonist of XIAP anti-Caspase activity

2001 • 434 citations

XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1-TAK1 in the BMP signaling pathway

1999 • 388 citations

Recruitment, activation and retention of caspases-9 and -3 by Apaf-1 apoptosome and associated XIAP complexes

2001 • 388 citations

NRAGE, A Novel MAGE Protein, Interacts with the p75 Neurotrophin Receptor and Facilitates Nerve Growth Factor–Dependent Apoptosis

2000 • 287 citations

Apoptosis Suppression by Raf-1 and MEK1 Requires MEK- and Phosphatidylinositol 3-Kinase-Dependent Signals

2001 • 181 citations

Necdin, A Postmitotic Neuron-specific Growth Suppressor, Interacts with Viral Transforming Proteins and Cellular Transcription Factor E2F1

1998 • 163 citations

Selective activation of JNK1 is necessary for the anti-apoptotic activity of hILP

1998 • 134 citations

v-raf suppresses apoptosis and promotes growth of interleukin-3-dependent myeloid cells.

1994 • 111 citations

The anti-apoptotic protein ITA is essential for NGF-mediated survival of embryonic chick neurons

1999 • 64 citations

The neuronal apoptosis inhibitory protein suppresses neuronal differentiation and apoptosis in PC12 cells

2000 • 64 citations

Inhibitor of apoptosis protein hILP undergoes caspase-mediated cleavage during T lymphocyte apoptosis.

2000 • 63 citations

Functional Characterization of the Murine Homolog of the B cell-specific Coactivator BOB.1/OBF.1

1995 • 59 citations

ITA, a Vertebrate Homologue of IAP That Is Expressed in T Lymphocytes

1996 • 33 citations

Interaction between the protein kinase B-Raf and the alpha-subunit of the 11S proteasome regulator.

1998 • 27 citations