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Identification of the Cystic Fibrosis Gene: Cloning and Characterization of Complementary DNA

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Recommendations for a nomenclature system for human gene mutations

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1994 • 700 citations

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1984 • 681 citations

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Faecal elastase 1: a novel, highly sensitive, and specific tubeless pancreatic function test.

1996 • 536 citations

Autoimmune-related pancreatitis is associated with autoantibodies and a Th1/Th2-type cellular immune response

2000 • 535 citations

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SPINK1/PSTI polymorphisms act as disease modifiers in familial and idiopathic chronic pancreatitis

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Mutations in the cationic trypsinogen gene are associated with recurrent acute and chronic pancreatitis

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1952 • 416 citations

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1965 • 408 citations

The natural history of pain in alcoholic chronic pancreatitis

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Course of alcoholic chronic pancreatitis: A prospective clinicomorphological long-term study

1996 • 352 citations

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1988 • 307 citations

Revised classification of pancreatitis

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A Prospective Study of Cigarette Smoking and the Risk of Pancreatic Cancer

1996 • 306 citations

AGA technical review: Treatment of pain in chronic pancreatitis

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Pancreatitis is a risk factor for pancreatic cancer

1995 • 290 citations

The genetic testing of children. Working Party of the Clinical Genetics Society (UK)

1994 • 282 citations

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1993 • 271 citations

Multicenter Survey of the Etiology of Pancreatic Diseases

1978 • 260 citations

A signal peptide cleavage site mutation in the cationic trypsinogen gene is strongly associated with chronic pancreatitis

1999 • 260 citations

Revised classification of pancreatitis. Report of the Second International Symposium on the Classification of Pancreatitis in Marseille, France, March 28-30, 1984.

1985 • 253 citations

Alcohol and smoking as risk factors in chronic pancreatitis and pancreatic cancer.

1999 • 251 citations

Pancreatitis, A Diagnostic Clue to Hyperparathyroidsm

1957 • 244 citations

CT-guided biopsy: prospective analysis of 1,000 procedures.

1989 • 236 citations

CT- and US-guided biopsy of the pancreas.

1993 • 229 citations

Fecal elastase test: evaluation of a new noninvasive pancreatic function test.

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The Pancreas in Primary Biliary Cirrhosis and Primary Sclerosing Cholanitis

1982 • 218 citations

Pancreatitis and Pancreatic Cancer: a Population-Based Study

1994 • 211 citations

Severe Chronic Pancreatitis versus Suspected Pancreatic Disease: Dynamic MR Cholangiopancreatography after Secretin Stimulation

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1994 • 206 citations

A Clinically Based Classification System for Alcoholic Chronic Pancreatitis

1997 • 202 citations

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1999 • 199 citations

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2000 • 199 citations

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2000 • 192 citations

Pancreatic Carcinoma versus Chronic Pancreatitis: Dynamic MR Imaging

1999 • 180 citations

Comparison of Endoscopic Retrograde Cholangiopancreatography with MR Cholangiopancreatography in Patients with Pancreatitis

1999 • 179 citations

Pancreatic Cancer Risk and Nutrition-Related Methyl-Group Availability Indicators in Male Smokers

1999 • 166 citations

Hyperparathyroidism and Pancreatitis

1980 • 160 citations

Chronic Pancreatitis and Inflammatory Bowel Disease: True Or Coincidental Association?

1999 • 158 citations

Endoscopic Ultrasonography in Chronic Pancreatitis

1995 • 158 citations

Investigation of the role of polymorphisms at the alcohol and aldehyde dehydrogenase loci in genetic predisposition to alcohol-related end-organ damage

1991 • 158 citations

Chronic pancreatitis associated with an activation peptide mutation that facilitates trypsin activation

2000 • 157 citations

The Pancreatitis Classification of Marseilles-Rome 1988

1989 • 156 citations

Computed Tomography of the Pancreas

1976 • 154 citations

Inheritance of Apolipoprotein C-II Deficiency with Hypertriglyceridemia and Pancreatitis

1978 • 153 citations

Frequent Occurrence of the CFTR Intron 8 (TG)n 5T Allele in Men with Congenital Bilateral Absence of the Vas Deferens

1995 • 150 citations

Endoscopic pancreatocholangiography. II. The pathological endoscopic pancreatocholangiogram.

1972 • 148 citations

Relationship between pancreatic exocrine function and ductal morphology in chronic pancreatitis

1982 • 142 citations

Cigarette smoking: an independent risk factor in alcoholic pancreatitis.

1996 • 137 citations

Pseudocysts in chronic pancreatitis: a morphological analysis of 57 resection specimens and 9 autopsy pancreata.

1991 • 137 citations

Pancreatic fibrosis in experimental pancreatitis induced by dibutyltin dichloride

1997 • 136 citations

Diagnostic Criteria for Chronic Pancreatitis by the Japan Pancreas Society

1997 • 133 citations

Minimal change chronic pancreatitis.

1992 • 133 citations

Acute hypercalcemia causes acute pancreatitis and ectopic trypsinogen activation in the rat

1995 • 132 citations

Fate of pancreatic enzymes during small intestinal aboral transit in humans

1986 • 132 citations

Pseudocysts in Chronic Pancreatitis

1991 • 132 citations

Cigarette Smoking as a Risk Factor for Chronic Pancreatitis: A Case-Control Study in Japan

2000 • 127 citations

Primary sclerosing cholangitis in Japan?analysis of 192 cases

1997 • 124 citations

Recurrent acute pancreatitis: An algorithmic approach to identification and elimination of inciting factors

2001 • 124 citations

Nationwide epidemiological survey of chronic pancreatitis in Japan

2000 • 122 citations

Incidence of Alcoholic Chronic Pancreatitis in Copenhagen

1982 • 120 citations

Hypertriglyceridaemia due to genetic defects in lipoprotein lipase and apolipoprotein C‐II

1992 • 120 citations

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1958 • 120 citations

Complications Related to Diagnostic and Therapeutic Endoscopic Retrograde Cholangiopancreatography

1996 • 119 citations

Is tobacco a risk factor for chronic pancreatitis and alcoholic cirrhosis?

1991 • 118 citations

Fecal elastase 1 determination in chronic pancreatitis.

1999 • 118 citations

Pancreatic adenocarcinoma: designing the examination to evaluate the clinical questions.

1992 • 118 citations

Endoscopic Pancreatocholangiography

1972 • 117 citations

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1971 • 116 citations

The Problem of Classification and Staging of Chronic Pancreatitis: Proposals Based on Current Knowledge of Its Natural History

1994 • 114 citations

Clinical characteristics of hereditary pancreatitis in a large family, based on high-risk haplotype. The Midwest Multicenter Pancreatic Study Group (MMPSG)

1997 • 111 citations

Chronic relapsing pancreatitis

1971 • 109 citations

Two Mutations in Rat Trypsin Confer Resistance against Autolysis

1998 • 107 citations

Inhibition of pancreatic secretion in man by cigarette smoking

1972 • 105 citations

Quantitative evaluation of pancreatic enhancement during dual-phase helical CT.

1995 • 102 citations

Cigarette Smoking

1996 • 102 citations

Pancreatitis and the Risk of Pancreatic Cancer

1995 • 101 citations

Hereditary pancreatitis in England and Wales.

1978 • 99 citations

Expression of an abundant alternatively spliced form of the cystic fibrosis transmembrane conductance regulator (CFTR) gene is not associated with a cAMP-activated chloride conductance

1993 • 99 citations

Endoscopic Ultrasonography of Chronic Pancreatitis and Pancreatic Pseudocysts

1986 • 98 citations

Copenhagen Pancreatitis Study

1981 • 97 citations

Mutations in exons 2 and 3 of the cationic trypsinogen gene in Japanese families with hereditary pancreatitis

1999 • 97 citations

Etiopathogenesis and definition of chronic pancreatitis

1986 • 96 citations

Chronic pancreatitis

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Autoimmune Pancreatitis

1998 • 94 citations

Correlation of Imaging and Function in Chronic Pancreatitis

1989 • 93 citations

Fecal Pancreatic Elastase 1 Is Inaccurate in the Diagnosis of Chronic Pancreatitis

1996 • 93 citations

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1994 • 93 citations

CHRONIC PANCREATITIS AND ALPHA-1-ANTITRYPSIN

1975 • 86 citations

Individual susceptibility to alcoholic pancreatitis: still an enigma.

1995 • 86 citations

Mutations in exon 3 of the lipoprotein lipase gene segregating in a family with hypertriglyceridemia, pancreatitis, and non-insulin-dependent diabetes.

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Pancreatic Enzymes: Secretion and Luminal Nutrient Digestion in Health and Disease

1999 • 84 citations

High Prevalence of Pancreatic Disease in Chronic Renal Failure

1977 • 82 citations

Hereditary Pancreatitis and Pancreatic Carcinoma

1999 • 82 citations

Hyperparathyroidism and Pancreatitis

1962 • 82 citations

Pancreatic lithiasis in the aged

1984 • 81 citations

Meningococcal septicaemia in a C6-deficient patient and effects of plasma transfusion on lipopolysaccharide release

1992 • 81 citations

Function tests in the diagnosis of chronic pancreatitis

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Sphincter of Oddi dysfunction

1996 • 79 citations

Definitions of Acute and Chronic Pancreatitis

1984 • 79 citations

Sphincter of Oddi dysfunction is associated with chronic pancreatitis.

1997 • 78 citations

GENETIC PREDISPOSITIONS TO ACUTE AND CHRONIC PANCREATITIS

2000 • 78 citations

Screening for mutations of the cationic trypsinogen gene: are they of relevance in chronic alcoholic pancreatitis?

1999 • 78 citations

DIAGNOSIS OF CHRONIC PANCREATITIS

1999 • 75 citations

Genotype and Phenotype in Cystic Fibrosis

1997 • 74 citations

Exocrine pancreatic function in correlation to ductal and parenchymal morphology in chronic pancreatitis.

1986 • 74 citations

Recovery of the pancreas after acute pancreatitis is not necessarily complete

1995 • 71 citations

Inhibition of nucleation and crystal growth of calcium carbonate by human lithostathine

1992 • 71 citations

Pancreatitis in a Native American Indian Population

1987 • 70 citations

Acute Pancreatitis in Patients With End-Stage Renal Disease Without Transplantation

1986 • 67 citations

CYSTIC FIBROSIS MUTATIONS AND GENETIC PREDISPOSITION TO IDIOPATHIC CHRONIC PANCREATITIS

2000 • 65 citations

Early trypsinogen activation in acute pancreatitis

1999 • 65 citations

Acute Interstitial Pancreatitis in Rats Induced by Dibutyltin Dichloride (DBTC)

1997 • 63 citations

Pancreatic Stone Protein (Lithostathine), a Physiologically Relevant Pancreatic Calcium Carbonate Crystal Inhibitor?

1997 • 61 citations

Chronic Pancreatitis in Mexico City

1990 • 61 citations

The association of primary hyperparathyroidism and pancreatitis.

1985 • 60 citations

GENETIC TESTING

2000 • 56 citations

A new polymorphism for the RI22H mutation in hereditary pancreatitis

2001 • 56 citations

Racial factors and the risk of chronic pancreatitis

1999 • 55 citations

Pancreatic exocrine function in severe human chronic renal failure.

1982 • 53 citations

Hereditary chronic relapsing pancreatitis

1967 • 53 citations

PANCREATIC ASPECTS OF CYSTIC FIBROSIS AND OTHER INHERITED CAUSES OF PANCREATIC DYSFUNCTION

2000 • 52 citations

Racial Factors and The Risk of Chronic Pancreatitis

1999 • 52 citations

The two human trypsinogens: Catalytic properties of the corresponding trypsins

1978 • 51 citations

A Review: Acute and Chronic Effects of Ethanol and Alcoholic Beverages on the Pancreatic Exocrine Secretion In Vivo and In Vitro

1998 • 51 citations

Proteolysis of human trypsinogen 1. Pathogenic implication in chronic pancreatitis

1984 • 50 citations

Smoking and Alcoholic Pancreatitis

1993 • 49 citations

A comparison of two injection protocols using helical and dynamic acquisitions in CT examinations of the pancreas.

1996 • 49 citations

A possible zymogen self-destruct mechanism preventing pancreatic autodigestion

1988 • 48 citations

Lack of R117H Mutation in the Cationic Trypsinogen Gene in Patients with Tropical Pancreatitis from Bangladesh

1998 • 47 citations

Motivations and Concerns of Patients With Access to Genetic Testing for Hereditary Pancreatitis

2001 • 47 citations

Hereditary Pancreatitis-associated Mutation Asn21 → Ile Stabilizes Rat Trypsinogen in Vitro

1999 • 46 citations

New concepts in understanding the pathophysiology of chronic pancreatitis

1998 • 45 citations

Sensitivity of endoscopic retrograde pancreatography in chronic pancreatitis

1982 • 45 citations

Alcohol consumption and divorce rates in the United States.

1999 • 44 citations

A Plea for Uniform Reporting of Patient Outcome in Chronic Pancreatitis

1996 • 43 citations

The Pancreolauryl Test

1982 • 42 citations

Optimized serum pancreolauryl test for differentiating patients with and without chronic pancreatitis

1998 • 41 citations

Etiology of chronic calcifying pancreatitis in Brazil: a report of 329 consecutive cases

1986 • 41 citations

Hyperparathyroidism associated with chronic pancreatitis in a family.

1968 • 40 citations

Increasing Incidence of Pancreatic Cancer Among Women in Olmsted County, Minnesota, 1940 Through 1988

1992 • 40 citations

Obstructive pancreatitis: Unusual causes of chronic pancreatitis

1988 • 38 citations

Pancreatic stellate cells: The new stars of chronic pancreatitis?

1998 • 38 citations

Evidence for an inherited predisposition to alcoholic pancreatitis

1984 • 37 citations

Hereditary Pancreatitis and Familial Pancreatic Cancer

1997 • 37 citations

2 Chronic pancreatitis and diabetes

1992 • 36 citations

GASTROINTESTINAL COMPLICATIONS OF RENAL FAILURE

1998 • 36 citations

Hereditary pancreatitis: new insights, new directions

1999 • 35 citations

Alpha 1 antitrypsin phenotypes and alcoholic pancreatitis.

1991 • 35 citations

The Natural History of Hereditary Chronic Pancreatitis

1998 • 35 citations

Does Acute Alcoholic Pancreatitis Exist without Preexisting Chronic Pancreatitis?

1997 • 31 citations

CHRONIC RELAPSING PANCREATITIS

1947 • 31 citations

Low Prevalence of Alterations in the Pancreatic Duct System in Patients with Primary Sclerosing Cholangitis

1996 • 31 citations

Magnetic resonance imaging with magnetic resonance cholangiopancreatography accurately predicts resectability of pancreatic carcinoma

1999 • 31 citations

HLA Antigens in Chronic Alcoholic Pancreatitis

1979 • 30 citations

The Course of Pancreatic Fibrosis Induced by Dibutyltin Dichloride (DBTC)

1999 • 30 citations

Recurrent pancreatitis and chylomicronemia in an extended Dutch kindred is caused by a Gly154–>Ser substitution in lipoprotein lipase.

1993 • 30 citations

PROGRESSION FROM ACUTE TO CHRONIC PANCREATITIS

1999 • 30 citations

PANCREATIC CANCER SURVEILLANCE IN A HIGH-RISK COHORT

2000 • 28 citations

3D-endosonography in gastroenterology: methodology and clinical applications

1999 • 28 citations

HLA-B13 and chronic calcific pancreatitis

1982 • 28 citations

Role of Alcohol Dehydrogenase Polymorphism in Ethanol Metabolism and Alcohol-Related Diseases

1990 • 27 citations

Apolipoprotein C‐ll deficiency syndrome due to apo C‐II_Hamburg: clinical and biochemical features and Hphl restriction enzyme polymorphism

1992 • 27 citations

Pancreolauryl test for pancreatic exocrine insufficiency.

1983 • 27 citations

Update on diagnosis and management of chronic pancreatitis

1999 • 26 citations

Gastric and Pancreatic Function in Patients with End-Stage Renal Disease

1982 • 26 citations

Effect of Chronic Ethanol Feeding on Digestive Enzyme Synthesis and mRNA Content in Rat Pancreas

1995 • 25 citations

Chronic Obstructive Pancreatitis as a Delayed Complication of Pancreatic Trauma

1991 • 25 citations

The influence of ethanol on long-term effects of dibutyltin dichloride (DBTC) in pancreas and liver of rats

1998 • 24 citations

Diagnosis of Chronic Pancreatitis

1982 • 24 citations

Histological pancreatitis in end-stage renal disease

1992 • 24 citations

Origin and development of exocrine pancreatic insufficiency in experimental renal failure.

1994 • 23 citations

Acute pancreatitis in chronic renal failure.

1996 • 23 citations

HLA antigens in chronic pancreatitis

1987 • 23 citations

Conference Report

1999 • 21 citations

Pancreatic lithiasis in the aged

1984 • 20 citations

Self-reported alcohol consumption among adolescents and the signification of early onset

1989 • 20 citations

THE ROLE OF ENDOSCOPY IN ACUTE RECURRENT AND CHRONIC PANCREATITIS AND PANCREATIC CANCER

1999 • 20 citations

Does Acute Pancreatitis Progress to Chronic Pancreatitis? A Microvascular Pancreatitis Model in the Rat

1995 • 20 citations

Sonographic changes of the pancreas in chronic renal failure

1989 • 18 citations

Chronic obstructive pancreatitis, nesidioblastosis, and small endocrine pancreatic tumor

1987 • 17 citations

Lithostathine messenger RNA expression in different types of chronic pancreatitis.

1998 • 17 citations

Acute Pancreatitis Is Not a Cause of Chronic Pancreatitis in the Absence of Residual Duct Strictures

1993 • 17 citations

Alcoholic pancreatitis: Unraveling the mystery

1995 • 16 citations

Effect of cigarette smoke on human serum trypsin inhibitory capacity and antitrypsin concentration.

1982 • 16 citations

HLA Antigen and Chronic Pancreatitis in Japan

1981 • 15 citations

Magnetic Resonance Pancreatography (MRP)

1999 • 14 citations

Surgical management of chronic pain from chronic pancreatitis.

1997 • 14 citations

The influence of ethanol on long-term effects of dibutyltin dichloride (DBTC) in pancreas and liver of rats

1998 • 14 citations

CT Demonstration of Fibrous Stroma in Chronic Pancreatitis: Pathologic Correlation

1999 • 12 citations

Sphincter of Oddi Dysfunction

2000 • 8 citations

Diagnosis of chronic pancreatitis

1998 • 7 citations

Molecular pathogenesis of chronic pancreatitis associated with abnormal CFTR genotypes

2000 • 6 citations

PREVENTIVE STRATEGIES AND THERAPEUTIC OPTIONS FOR HEREDITARY PANCREATITIS

2000 • 6 citations

Chronic and relapsing acute pancreatitis associated with chronic renal insufficiency and analgesic (phenacetin) abuse. Observations in 4 patients.

1981 • 6 citations

Chronische Pankreatitis: Update Diagnostik und Therapie

2021 • 4 citations

Novel Approaches to the Diagnosis of Pancreatic Disease in Childhood

1997 • 2 citations

Pain Management in chronic pancreatitis

1999 • 2 citations

4589 How much experience is required to correctly interpret eus features of chronic pancreatitis? a multicenter prospective trial of third tier eus trainees compared to a consensus of experts.

2000 • 1 citations

Invasive pancreatic function testing: a survey of methods and number of procedures performed in the United States

2000 • 1 citations

Invasive pancreatic function testing: a survey of methods and number of procedures performed in the United States

2000 • 1 citations