Regulation of gene expression by transfected subunits of cAMP‐dependent protein kinase

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

DNA cloning : a practical approach

1985 • 2,302 citations

PROTEIN SERINE/THREONINE KINASES

1987 • 1,457 citations

Identification of a cyclic-AMP-responsive element within the rat somatostatin gene.

1986 • 1,424 citations

Binding of a nuclear protein to the cyclic-AMP response element of the somatostatin gene

1987 • 1,364 citations

Identification of two distinct regulatory regions adjacent to the human β-interferon gene

1983 • 1,076 citations

Cyclic AMP and the induction of eukaryotic gene transcription.

1988 • 1,041 citations

Transient accumulation of c-fos RNA following serum stimulation requires a conserved 5′ element and c-fos 3′ sequences

1985 • 871 citations

Cyclic AMP Receptor Protein: Role in Transcription Activation

1984 • 645 citations

Injection of subunits of cyclic AMP-dependent protein kinase into cardiac myocytes modulates Ca2+ current

1982 • 421 citations

Regulatory Mechanisms in the Control of Protein Kinase

1982 • 357 citations

Proteins bound at adjacent DNA elements act synergistically to regulate human proenkephalin cAMP inducible transcription.

1988 • 342 citations

Phosphorylation fails to activate chloride channels from cystic fibrosis airway cells

1987 • 341 citations

Microinjection of catalytic subunit of cyclic AMP-dependent protein kinase enhances calcium action potentials of bag cell neurons in cell culture

1980 • 306 citations

Evidence for a second isoform of the catalytic subunit of cAMP-dependent protein kinase.

1986 • 286 citations

Isolation of cDNA clones coding for the catalytic subunit of mouse cAMP-dependent protein kinase.

1986 • 275 citations

The mouse metallothionein-I gene is transcriptionally regulated by cadmium following transfection into human or mouse cells

1982 • 265 citations

A family of immunologically related transcription factors that includes multiple forms of ATF and AP-1.

1988 • 259 citations

Structural determinants for transcriptional activation by cAMP-responsive DNA elements.

1988 • 258 citations

Molecular cloning, cDNA structure, and regulation of the regulatory subunit of type II cAMP-dependent protein kinase from rat ovarian granulosa cells.

1986 • 254 citations

[Progress in endocrinology].

1988 • 248 citations

Regulation of transcription by cyclic AMP-dependent protein kinase.

1989 • 247 citations

Identification of a region in the human vasoactive intestinal polypeptide gene responsible for regulation by cyclic AMP.

1987 • 236 citations

Cyclic-AMP-dependent protein kinase type II is associated with the Golgi complex and with centrosomes

1985 • 234 citations

The molecular cloning of a type II regulatory subunit of the cAMP-dependent protein kinase from rat skeletal muscle and mouse brain.

1987 • 223 citations

Genetic characterization of a brain-specific form of the type I regulatory subunit of cAMP-dependent protein kinase.

1988 • 212 citations

A Protein Kinase Inhibitor Gene Reduces Both Basal and Multihormone-stimulated Prolactin Gene Transcription

1989 • 203 citations

Heterogeneous distribution of the cAMP receptor protein RII in the nervous system: evidence for its intracellular accumulation on microtubules, microtubule-organizing centers, and in the area of the Golgi complex.

1986 • 197 citations

Expression of cDNAs for two isoforms of the catalytic subunit of cAMP-dependent protein kinase.

1987 • 194 citations

The catalytic subunit of cAMP-dependent protein kinase induces expression of genes containing cAMP-responsive enhancer elements

1988 • 186 citations

Isolation of a cDNA clone for the type I regulatory subunit of bovine cAMP-dependent protein kinase.

1983 • 177 citations

Interleukin 1 and cyclic AMP induce kappa immunoglobulin light-chain expression via activation of an NF-kappa B-like DNA-binding protein.

1989 • 176 citations

Both Isoforms of the cAMP-dependent Protein Kinase Catalytic Subunit Can Activate Transcription of the Prolactin Gene

1989 • 162 citations

A method for increasing the sensitivity of chloramphenicol acetyltransferase assays in extracts of transfected cultured cells

1987 • 161 citations

Interaction of cAMP with the cell-surface receptor induces cell-type-specific mRNA accumulation in Dictyostelium discoideum.

1986 • 139 citations

Recombinant Fragment of Protein Kinase Inhibitor Blocks Cyclic AMP-Dependent Gene Transcription

1987 • 139 citations

Mechanisms of trans-synaptic regulation of gene expression

1987 • 125 citations

Molecular Cloning, Complementary Deoxyribonucleic Acid Structure and Predicted Full-Length Amino Acid Sequence of the Hormone-lnducible Regulatory Subunit of 3′-5′-Cyclic Adenosine Monophosphate-Dependent Protein Kinase from Human Testis

1988 • 124 citations

The phosphoform of the regulatory subunit RII of cyclic AMP-dependent protein kinase possesses intrinsic topoisomerase activity

1985 • 103 citations

cAMP induction of prespore and prestalk gene expression in Dictyostelium is mediated by the cell-surface cAMP receptor.

1986 • 86 citations

Bovine leukemia virus trans-activator p38tax activates heterologous promoters with a common sequence known as a cAMP-responsive element or the binding site of a cellular transcription factor ATF.

1989 • 81 citations

pSV00CAT: low background CAT plasmid

1988 • 75 citations

Transfection of neonatal rat Schwann cells with SV-40 large T antigen gene under control of the metallothionein promoter.

1987 • 73 citations

Relationship between NGF-mediated volume increase and “priming effect” in fast and slow reacting clones of PC12 pheochromocytoma cells

1983 • 70 citations

Protein phosphorylation and the regulation of ion channels

1983 • 57 citations

Catalytic subunit of cAMP‐dependent protein kinase is essential for cAMP‐mediated mammalian gene expression

1988 • 41 citations

The binding of the cyclic AMP receptor protein to synthetic DNA sites containing permutations in the consensus sequence TGTGA

1987 • 38 citations

Separation of Topoisomerase I Activity from the Regulatory Subunit of Type II CyclicAdenosine Monophosphate-Dependent Protein Kinase

1988 • 6 citations