Pharmacological properties of ATP-sensitive K+ channels in mammalian skeletal muscle cells

ATP-regulated K+ channels in cardiac muscle

1983 • 2,350 citations

Intracellular ATP directly blocks K+ channels in pancreatic B-cells

1984 • 1,199 citations

Hyperpolarizing Vasodilators Activate ATP-sensitive K ⁺ Channels in Arterial Smooth Muscle

1989 • 1,197 citations

Opposite effects of tolbutamide and diazoxide on the ATP-dependent K+ channel in mouse pancreatic ?-cells

1986 • 572 citations

THE SULPHONYLUREA RECEPTOR MAY BE AN ATP-SENSITIVE POTASSIUM CHANNEL

1985 • 507 citations

The receptor for antidiabetic sulfonylureas controls the activity of the ATP-modulated K+ channel in insulin-secreting cells.

1987 • 452 citations

Voltage-dependent ATP-sensitive potassium channels of skeletal muscle membrane

1985 • 417 citations

Antidiabetic sulfonylureas control action potential properties in heart cells via high affinity receptors that are linked to ATP-dependent K+ channels.

1988 • 292 citations

Moving together: K+ channel openersand ATP-sensitive K+ channels

1989 • 285 citations

Adenosine-5′-triphosphate-sensitive ion channels in neonatal rat cultured central neurones

1988 • 270 citations

Antidiabetic sulfonylureas: localization of binding sites in the brain and effects on the hyperpolarization induced by anoxia in hippocampal slices

1989 • 237 citations

The potassium channel opener cromakalim (BRL 34915) activates ATP-dependent K+ channels in isolated cardiac myocytes

1988 • 193 citations

BRL 34915 (cromakalim) activates ATP-sensitive K+ current in cardiac muscle.

1988 • 193 citations

ATP-dependent potassium channels of muscle cells: Their properties, regulation, and possible functions

1991 • 147 citations

Interaction of diazoxide, tolbutamide and ATP4− on nucleotide-dependent K+ channels in an insulin-secreting cell line

1987 • 132 citations

On the mechanism of nucleotide diphosphate activation of the ATP‐sensitive K+ channel in ventricular cell of guinea‐pig.

1991 • 132 citations

Potassium channel activator drugs: Mechanism of action, pharmacological properties, and therapeutic potential

1992 • 130 citations

Potassium channel openers: pharmacological and clinical aspects

1992 • 124 citations

A specific binding site for K+ channel openers in rat aorta.

1992 • 118 citations

Potassium channel openers act through an activation of ATP-sensitive K+ channels in guinea-pig cardiac myocytes

1989 • 116 citations

Recent progress in potassium channel opener pharmacology

1992 • 113 citations

Cardiovascular and biological effects of K+ channel openers, a class of drugs with vasorelaxant and cardioprotective properties

1990 • 110 citations

Activation of ATP-sensitive outward K+ current by nicorandil (2-nicotinamidoethyl nitrate) in isolated ventricular myocytes.

1989 • 100 citations

Effect of channel blockers on potassium efflux from metabolically exhausted frog skeletal muscle.

1987 • 100 citations

Skeletal muscle ATP-sensitive K+ channels recorded from sarcolemmal blebs of split fibers: ATP inhibition is reduced by magnesium and ADP

1991 • 82 citations

ATP-sensitive potassium channels in adult mouse skeletal muscle: Characterization of the ATP-binding site

1989 • 76 citations

Multiple actions of pinacidil on adenosine triphosphate‐sensitive potassium channels in guinea‐pig ventricular myocytes.

1990 • 71 citations

ATP-sensitive potassium channels in adult mouse skeletal muscle: Different modes of blockage by internal cations, ATP and tolbutamide

1989 • 70 citations

Activation of ATP-sensitive K channels in heart cells by pinacidil: dependence on ATP

1989 • 64 citations

Essential role of nucleotide diphosphates in nicorandil-mediated activation of cardiac ATP-sensitive K+ channel. A comparison with pinacidil and lemakalim.

1991 • 62 citations

Interrelation between pinacidil and intracellular ATP concentrations on activation of the ATP-sensitive K+ current in guinea pig ventricular myocytes.

1990 • 59 citations

Cromakalim (BRL 34915) restores in vitro the membrane potential of depolarized human skeletal muscle fibres

1989 • 57 citations

Pinacidil activates the ATP-sensitive K+ channel in inside-out and cell-attached patch membranes of guinea-pig ventricular myocytes

1990 • 52 citations

Nucleotide diphosphates activate the ATP-sensitive potassium channel in mouse skeletal muscle

1992 • 46 citations

Effects of potassium channel openers on single potassium channels in mouse skeletal muscle

1990 • 42 citations

Activation of ATP-sensitive K channels by a K channel opener (SR 44866) and the effect upon electrical and mechanical activity of frog skeletal muscle

1991 • 27 citations

Two different types of potassium channels in human skeletal muscle activated by potassium channel openers

1990 • 27 citations

K+ channel openers suppress myotonic activity of human in vitro

1990 • 26 citations

Selective modulation of the ATP-sensitive K+ channel by nicorandil in guinea-pig cardiac cell membrane

1990 • 20 citations

SALTS OF MORPHINE. ADMINISTRATION OF MERCURY. CONSTIPATION.

1838 • 13 citations

Ion channels ten years of patch-clamp studies

1992 • 11 citations