Studies on liver mitochondrial 5′-endonuclease activity in rats fed carcinogenic amines and on their binding to mitochondrial proteins

Tissue fractionation studies. 6. Intracellular distribution patterns of enzymes in rat-liver tissue

1955 • 4,109 citations

[73] Spectrophotometric and turbidimetric methods for measuring proteins

1957 • 3,309 citations

The Metabolic Activation of Carcinogenic Aromatic Amines and Amides1

2015 • 349 citations

On the mechanism of action of carcinogenic aromatic amines

1969 • 138 citations

The carcinogenicity of compounds related to 2-acetylaminofluorene. II. Variations in the bridges and the 2-substituent.

1955 • 135 citations

Preferential alkylation of mitochondrial deoxyribonucleic acid by N-methyl-N-nitrosourea

1970 • 130 citations

Reaction of esters of aromatic -hydroxy amines and amides with methionine : A model for binding of amine carcinogens to protein

1966 • 125 citations

N-Benzoyloxy-N-methyl-4-aminoazobenzene: its carcinogenic activity in the rat and its reactions with proteins and nucleic acids and their constituents in vitro.

1967 • 98 citations

CORRELATION OF THE LEVEL OF HEPATIC RIBOFLAVIN WITH THE APPEARANCE OF LIVER TUMORS IN RATS FED AMINOAZO DYES

1948 • 86 citations

Chemical carcinogenesis: mechanisms and approaches to its control.

1971 • 82 citations

Zelluläre Speicherung cancerogener Kohlenwasserstoffe

1939 • 81 citations

CELLULAR POPULATIONS AND MITOTIC ACTIVITY IN RAT LIVER PARENCHYMA DURING AZO DYE CARCINOGENESIS.

1964 • 80 citations

Studies on the intracellular composition of livers from rats fed various aminoazo dyes; 3'-methyl-,2'-methyl-, and 2-methyl-4-dimethylaminoazobenzene,3-methyl-4-monomethylaminoazobenzene, and 4'-fluoro-4-dimethylaminoazobenzene.

1950 • 79 citations

STUDIES ON THE MECHANISM OF ACTIVATION OF AROMATIC AMINE AND AMIDE CARCINOGENS TO ULTIMATE CARCINOGENIC ELECTROPHILIC REACTANTS

1969 • 79 citations

The purification from rat liver of a nuclease hydrolysing ribonucleic acid and deoxyribonucleic acid

1966 • 75 citations

3-Methylmercapto-N-methyl-4-aminoazobenzene: An alkaline-degradation product of a labile protein-bound dye in the livers of rats fed N,N-dimethyl-4-aminoazobenzene

1965 • 69 citations

Incorporation of High Molecular Weight Polynucleotides by Isolated Mitochondria

1971 • 67 citations

Hyperbasophilic foci as sites of neoplastic transformation in hepatic parenchyma.

1971 • 59 citations

Dehydroxylation and deacetylation of N-hydroxy-N-2-fluorenylacetamide by rat liver and brain homogenates

1965 • 55 citations

Autodegradation of ribonucleic acid of rat-liver microsomes

1965 • 32 citations

Intracellular distribution of 5′-ribonuclease and 5′-phosphodiesterase in rat liver

1967 • 28 citations

Partial purification and some properties of a 5′RNase from rat liver mitochrondrial fraction

1967 • 22 citations

On the interaction of mitochondrial protein synthesizing system with template ribonucleic acid of nuclear origin

1973 • 19 citations

Binding of dimethylaminoazobenzene metabolites to DNA and proteins. I. in vitro studies on a microsomal dependent system

1970 • 18 citations

Studies on the binding of tritiated p-dimethylaminoazobenzene in rat liver and the role of intranuclear binding sites in the early stages of carcinogenesis

1965 • 14 citations

Presence of Rous sarcoma virus inside the mitochondria isolated by zonal and differential centrifugation from Rous sarcoma cells.

1971 • 13 citations

Studies on the localization of rat liver mitochondrial 5′-endonuclease

1969 • 12 citations

Intracellular distribution of 5'-ribonuclease and 5'-phosphodiesterase in the Novikoff hepatoma ascites cells.

1967 • 9 citations

Migration of Nuclear RNA into Isolated Mouse Liver Mitochondria

1972 • 7 citations

Inhibition of mitochondrial 5′-endonuclease activity by carcinogenic amines and their N-oxidized derivatives

1972 • 2 citations