Immunoregulatory activity of the T-cell receptor alpha chain demonstrated by retroviral gene transfer.

Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus

1983 • 1,857 citations

Identification of a monoclonal antibody specific for a murine T3 polypeptide.

1987 • 1,644 citations

Redesign of Retrovirus Packaging Cell Lines To Avoid Recombination Leading to Helper Virus Production

1986 • 1,276 citations

The Use of the Avidin‐Biotin Complex as a Tool in Molecular Biology

1980 • 611 citations

Expression of a foreign gene in myeloid and lymphoid cells derived from multipotent haematopoietic precursors

1985 • 598 citations

Immunization with a synthetic T-cell receptor V-region peptide protects against experimental autoimmune encephalomyelitis

1989 • 588 citations

Transfer of specificity by murine α and β T-cell receptor genes

1986 • 568 citations

Vaccination Against Experimental Allergic Encephalomyelitis with T Cell Receptor Peptides

1989 • 416 citations

Anti-Idiotypic Network Induced by T Cell Vaccination Against Experimental Autoimmune Encephalomyelitis

1988 • 409 citations

A T cell receptor Vβ segment that imparts reactivity to a class II major histocompatibility complex product

1987 • 408 citations

Genomic organization and sequence of T-cell receptor β-chain constant- and joining-region genes

1984 • 377 citations

Suppression of experimentally induced autoimmune encephalomyelitis by cytolytic T–T cell interactions

1988 • 324 citations

Two better cell lines for making hybridomas expressing specific T cell receptors.

1989 • 300 citations

The structure, rearrangement and expression of Dβ gene segments of the murine T-cell antigen receptor

1984 • 290 citations

The murine T-cell receptor uses a limited repertoire of expressed Vβ gene segments

1985 • 283 citations

Building a multichain receptor: synthesis, degradation, and assembly of the T-cell antigen receptor.

1987 • 232 citations

Diversity and structure of genes of the α family of mouse T-cell antigen receptor

1985 • 228 citations

A Peptide Sequence Confers Retention and Rapid Degradation in the Endoplasmic Reticulum

1990 • 219 citations

Predominant use of a Vα gene segment in mouse T-cell receptors for cytochrome c

1986 • 206 citations

The presumptive CDR3 regions of both T cell receptor alpha and beta chains determine T cell specificity for myoglobin peptides.

1990 • 183 citations

Surface expression of the beta T cell receptor (TCR) chain in the absence of other TCR or CD3 proteins on immature T cells.

1991 • 121 citations

Sequence and expression of transcripts of the T-cell antigen receptor alpha-chain gene in a functional, antigen-specific suppressor-T-cell hybridoma.

1986 • 118 citations

Expression of a hybrid immunoglobulin-T cell receptor protein in transgenic mice

1989 • 111 citations

Two monoclonal rat antibodies with specificity for the beta-chain variable region V beta 6 of the murine T-cell receptor.

1988 • 100 citations

The T cell receptor V?3 gene segment is associated with reactivity to p-azobenzenearsonate

1988 • 76 citations

Predominant use of a particular α-chain in suppressor T cell hybridomas specific for keyhole limpet hemocyanin

1989 • 62 citations

Predictable acquisition of a new MHC recognition specificity following expression of a transfected T-cell receptor β-chain gene

1987 • 58 citations

Fine specificity of antigen recognition by T cell hybridoma clones specific for poly-18: a synthetic polypeptide antigen of defined sequence and conformation.

1985 • 48 citations

Specific inhibition of cell-surface T-cell receptor expression by antisense oligodeoxynucleotides and its effect on the production of an antigen-specific regulatory T-cell factor.

1989 • 45 citations

Cloned suppressor T cells derived from mice tolerized with conjugates of antigen and monomethoxypolyethylene glycol. Relationship between monoclonal T suppressor factor and the T cell receptor.

1990 • 41 citations

Transport and secretion of truncated T cell receptor beta-chain occurs in the absence of association with CD3.

1990 • 30 citations

The transmembrane anchor of the T-cell antigen receptor beta chain contains a structural determinant of pre-Golgi proteolysis.

1990 • 30 citations

Expression of functional alpha beta T cell receptor gene rearrangements in suppressor T cell hybridomas correlates with antigen binding, but not with suppressor cell function.

1990 • 24 citations

Antigen-Specific Helper Function of Cell-Free T Cell Products Bearing TCR V_β8 Determinants

1989 • 24 citations

A T helper cell hybridoma produces an antigen-specific regulatory activity. Relationship to the T cell receptor by serology and antigenic fine specificity.

1991 • 23 citations

DNP-specific/class I MHC-restricted suppressor molecules bear determinants of the T cell receptor alpha- and beta-chains. The V beta 8+ chain dictates restriction to either K or D.

1990 • 20 citations

An antigen-specific helper T cell hybridoma produces an antigen-specific suppressor inducer molecule with identical antigenic fine specificity. Implications for the antigen recognition and function of helper and suppressor inducer T cells.

1988 • 20 citations

Relationship between T cell receptors and antigen-binding factors. II. Common antigenic determinants and epitope recognition shared by T cell receptors and antigen-binding factors.

1989 • 17 citations

Critical role of an amino acid residue in a T cell determinant is due to its interaction with a neighboring non‐critical residue

1990 • 13 citations

Antigen/major histocompatibility complex-specific activation of murine T cells transfected with functionally rearranged T-cell receptor genes.

1987 • 11 citations

A novel strategy for the generation of T cell lines lacking expression of endogenous alpha- and/or beta-chain T cell receptor genes.

1991 • 9 citations

Serologic, biologic, and western blot analysis of a T suppressor factor with specificity for the hapten 4-hydroxy-3-nitrophenyl acetyl derived from serum-free medium.

1990 • 3 citations