Why Monitor Serum Levels of Gentamicin?

Experience in Monitoring Gentamicin Therapy during Treatment of Serious Gram-Negative Sepsis

1974 • 359 citations

Pharmacokinetics of dosing regimens which utilize multiple intravenous infusions: Gentamicin in burn patients

1976 • 356 citations

Gentamicin Blood Levels: a Guide to Nephrotoxicity

1975 • 314 citations

The Nephrotoxicity of Antimicrobial Agents

1977 • 312 citations

Controlled Comparison of Amikacin and Gentamicin

1977 • 262 citations

Ototoxicity of Gentamicin in Man: A Survey and Controlled Analysis of Clinical Experience in the United States

1971 • 245 citations

Antibacterial Activity in Serum and Urine as a Therapeutic Guide in Bacterial Infections

1974 • 238 citations

Renal Parenchymal Accumulation of Aminoglycoside Antibiotics in Rats

1974 • 195 citations

Gentamicin Serum Concentrations: Pharmacokinetic Predictions

1976 • 193 citations

The Influence of Dosage Regimen on Experimental Gentamicin Nephrotoxicity: Dissociation of Peak Serum Levels from Renal Failure

1979 • 184 citations

Pharmacokinetics of Gentamicin: Distribution and Plasma and Renal Clearance

1971 • 179 citations

Pharmacology of Gentamicin in Man

1971 • 174 citations

Pharmacokinetics of Gentamicin in Children and Adults

1975 • 160 citations

Infections in cancer patients.Results with gentamicin sulfate therapy

1972 • 151 citations

Serum Protein Binding of the Aminoglycoside Antibiotics

1972 • 142 citations

Gentamicin Dosages for Renal Insufficiency

1971 • 141 citations

Pseudomonas Bacteremia: Pharmacologic and Other Bases for Failure of Treatment with Gentamicin

1971 • 139 citations

Predictability of Blood Levels of Gentamicin in Man

1975 • 137 citations

PHARMACOLOGY OF GENTAMICIN, A NEW BROAD-SPECTRUM ANTIBIOTIC.

1963 • 130 citations

Relation between Dose and Levels of Gentamicin in Blood

1971 • 128 citations

The Unpredictability of Serum Concentrations of Gentamicin: Pharmacokinetics of Gentamicin in Patients with Normal and Abnormal Renal Function

1974 • 125 citations

Correlation of Serum Creatinine Concentration and Gentamicin Half-Life

1972 • 121 citations

Ototoxicity of Amikacin

1976 • 118 citations

Gentamicin: toxicity in perspective.

1974 • 113 citations

Renal Failure, Drug Pharmacokinetics and Drug Action

1976 • 110 citations

Pharmacokinetics and Ototoxicity of Gentamicin, Tobramycin, and Amikacin

1976 • 109 citations

Activity of Five Aminoglycoside Antibiotics In Vitro Against Gram-Negative Bacilli and Staphylococcus aureus

1973 • 109 citations

Gentamicin Sulfate Pharmacokinetics: Lower Levels of Gentamicin in Blood during Fever

1975 • 102 citations

Concentrations of Gentamicin and Amikacin in Human Kidneys

1976 • 95 citations

Inactivation of Gentamicin by Penicillins in Patients with Renal Failure

1976 • 78 citations

Penetration of antimicrobial agents into bronchial secretions

1975 • 78 citations

Therapeutic trials with tobramycin

1974 • 75 citations

Pharmacologic Factors Associated with Gentamicin Nephrotoxicity in Rabbits

1977 • 71 citations

Amikacin therapy of infections in neutropenic patients

1975 • 63 citations

Short-Term Storage of Six Penicillins and Cephalothin in Microdilution Trays for Antimicrobial Susceptibility Tests

1976 • 63 citations

Prospective Comparative Study of Variable Dosage and Variable Frequency Regimens for Administration of Gentamicin

1975 • 61 citations

Radioimmunoassay for Measurement of Gentamicin in Blood

1973 • 61 citations

Gas—liquid chromatographic method for the assay of aminoglycoside antibiotics in serum

1978 • 59 citations

Drug therapy reviews: Antimicrobial spectrum, pharmacology and therapeutic use of antibiotics, part 4: Aminoglycosides

1977 • 57 citations

Cephalosporin and Aminoglycoside Concentrations in Peritoneal Capsular Fluid in Rabbits

1976 • 57 citations

Levels of Carbenicillin, Ticarcillin, Cephalothin, Cefazolin, Cefamandole, Gentamicin, Tobramycin, and Amikacin in Human Serum and Interstitial Fluid

1977 • 56 citations

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

2010 • 56 citations

High-performance liquid chromatographic determination of kanamycin

1976 • 53 citations

Reappraisal of kanamycin usage in neonates

1975 • 50 citations

Gentamicin in Newborn Infants

1973 • 48 citations

Retrospective study of the ototoxicity of gentamicin.

1973 • 47 citations

Enzymatic Assay for Gentamicin and Related Aminoglycoside Antibiotics

1974 • 44 citations

Combined Use of Gentamicin and Carbenicillin

1971 • 38 citations

Radioimmunoassay of Iodinated Tobramycin

1976 • 38 citations

Amikacin for Treatment of Infections In Patients with Malignant Diseases

1976 • 37 citations

Simple Method for Elimination of Aminoglycosides from Serum to Permit Bioassay of Other Antimicrobial Agents

1977 • 36 citations

Clearance of Gentamicin during Hemodialysis: Comparison of Four Artificial Kidneys

1976 • 36 citations

Aspects of the Chronic Toxicity of Gentamicin Sulfate in Cats

1971 • 35 citations

Concentration of gentamicin in serum, urine and urogenital tissue in man.

1973 • 35 citations

Gentamicin, A New Aminoglycoside Antibiotic: Clinical and Laboratory Studies in Urinary Tract Infection

1969 • 34 citations

In Vitro Activity, Synergism, and Testing Parameters of Amikacin, with Comparisons to Other Aminoglycoside Antibiotics

1976 • 33 citations

Comparison of Five Aminocyclitol Antibiotics In Vitro Against Enterobacteriaceae and Pseudomonas

1973 • 33 citations

Gentamicin Intravenous Infusion Rate: Effect on Interstitial Fluid Concentration

1977 • 32 citations

In Vitro Evaluation of a New Aminoglycoside Derivative of Kanamycin, BB-KA: a Comparison with Tobramycin and Gentamycin

1973 • 31 citations

Penetration of Tobramycin into Infected Extravascular Fluids and Its Therapeutic Effectiveness

1977 • 31 citations

Computer Assisted Prescribing of Drugs

1976 • 30 citations

Serum streptomycin levels and dizziness

1970 • 30 citations

Immediate effects of tobramycin on human cochlea and correlation with serum tobramycin levels.

1977 • 28 citations

Gentamicin in Serious Neonatal Infections: Absorption, Excretion, and Clinical Results in 25 Cases

1971 • 28 citations

Safety of the Bolus Administration of Gentamicin

1976 • 27 citations

The ototoxicity of gentamicin.

1973 • 25 citations

Clinical Pharmacology of Gentamicin in Infants 2 to 24 Months of Age

1972 • 25 citations

Pharmacokinetics of Amikacin in Patients with Renal Insufficiency: Relation of Half-Life and Creatinine Clearance

1976 • 25 citations

Gentamicin and Ampicillin in Human Bile

1971 • 24 citations

Comparison of Enzymatic and Microbiological Gentamicin Assays

1974 • 20 citations

Pharmacology of Gentamicin in the Biliary Tract of Humans

1973 • 19 citations

Pharmacokinetic Analysis of Gentamicin Dosage Regimens Recommended for Renal Impairment

1975 • 18 citations

Amikacin Therapy for Severe Gram-Negative Sepsis: Efficacy in Infections Involving Gentamicin-Resistant Organisms

1976 • 18 citations

Distribution of Gentamicin in Body Fluids

1968 • 18 citations

Specific Assay of Aminoglycosidic- or Polymyxin-Type Antibiotics Present in Human Sera in Combination with Cephalosporins

1971 • 17 citations

Four-Hour Microbiological Assay of Gentamicin in Serum

1972 • 16 citations

Comparative Penetration of Amikacin, Gentamicin, and Penicillin G into Exudate Fluid in Experimental Sterile Peritonitis

1977 • 16 citations

Antimicrobial spectrum, pharmacology, and therapeutic use of antibiotics. IV. Aminoglycosides.

1977 • 16 citations

A Comparison of Two Methods of Gentamicin Assay: An Enzymatic Procedure and an Agar Diffusion Technique

1974 • 16 citations

Antibiotic concentrations in hepatic interstitial and wound fluid.

1976 • 16 citations

Which gentamicin assay method is the most practicable?

1977 • 16 citations

Factors affecting plate assay of gentamicin I Diluents

1975 • 15 citations

Effect of heparin on gentamicin concentration in blood

1972 • 13 citations

Assay of Aminoglycoside Antibiotics in Clinical Specimens

1975 • 13 citations

Antimicrobial Agents and Chemotherapy—1970.

1972 • 11 citations

Comparison of the <i>in vitro</i> Activities of BB-K8 and Three Other Ammoglycosides against 215 Strains of Pseudomonas and <i>Enterobacteriacea</i><i>e</i> with Variable Sensitivity to Kanamycin and Gentamicin

1975 • 11 citations

Pseudomonas bacteremia. Evaluation of factors influencing response to therapy.

1973 • 9 citations

Amikacin treatment of pulmonary infections involving gentamicin-resistant gram-negative bacilli

1977 • 9 citations

Assay for Gentamicin

1972 • 8 citations

Enzymatic Adenylylation by Aminoglycoside 4′-Adenylyltransferase and 2′′-Adenylyltransferase as a Means of Determining Concentrations of Aminoglycoside Antibiotics in Serum

1976 • 7 citations

Factors affecting plate assay of gentamicin. II. Media

1977 • 6 citations

Gentamicin therapy administered by intermittent intravenous injections.

1973 • 6 citations

Aspects of the pharmacology of gentamicin during the neonatal period.

1973 • 5 citations

Alleged Effect of Bile Constituents on Gentamicin Assays

1974 • 3 citations

Inhibition of Acetylating Activity in an Enzymatic Assay for Aminoglycoside Antibiotics

1977 • 3 citations

More on Idiopathic Hirsutism

1976 • 3 citations

[A new broad-spectrum antibiotic].

1971 • 3 citations

Error in Recovery Rate of Aminoglycosides from Uraemic Sera

1977 • 2 citations

POTENTIAL PITFALL IN BIOASSAY OF SERUM-GENTAMICIN

1975 • 2 citations

POTENTIAL PITFALL IN BIOASSAY OF SERUM-GENTAMICIN

1975 • 1 citations