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Binding of the Fap2 Protein of Fusobacterium nucleatum to Human Inhibitory Receptor TIGIT Protects Tumors from Immune Cell Attack

Data up to Jan 2025

Published2015
Citations1,026
References32

Total Citations Per Year

Abstract

References (32)

Hallmarks of Cancer: The Next Generation

2011 • 58,651 citations

The interaction of TIGIT with PVR and PVRL2 inhibits human NK cell cytotoxicity

2009 • 3,506 citations

Innate or Adaptive Immunity? The Example of Natural Killer Cells

2011 • 2,477 citations

Fusobacterium nucleatum Potentiates Intestinal Tumorigenesis and Modulates the Tumor-Immune Microenvironment

2013 • 2,151 citations

Fusobacterium nucleatum Promotes Colorectal Carcinogenesis by Modulating E-Cadherin/β-Catenin Signaling via its FadA Adhesin

2013 • 1,805 citations

Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma

2011 • 1,730 citations

Genomic analysis identifies association of Fusobacterium with colorectal carcinoma

2011 • 1,698 citations

Microbial Dysbiosis in Colorectal Cancer (CRC) Patients

2011 • 769 citations

Microbes, Microbiota, and Colon Cancer

2014 • 724 citations

Invasive potential of gut mucosa-derived fusobacterium nucleatum positively correlates with IBD status of the host

2011 • 494 citations

Mobile Microbiome

2013 • 409 citations

Fusobacterium nucleatum Induces Premature and Term Stillbirths in Pregnant Mice: Implication of Oral Bacteria in Preterm Birth

2004 • 409 citations

The Treatment of Inoperable Sarcoma by Bacterial Toxins (the Mixed Toxins of the Streptococcus erysipelas and the Bacillus prodigiosus).

1910 • 405 citations

Adoptive Transfer of Tumor-Infiltrating Lymphocytes in Patients with Metastatic Melanoma: Intent-to-Treat Analysis and Efficacy after Failure to Prior Immunotherapies

2013 • 352 citations

Activating natural cytotoxicity receptors of natural killer cells in cancer and infection

2013 • 288 citations

Recruitment of Grb2 and SHIP1 by the ITT-like motif of TIGIT suppresses granule polarization and cytotoxicity of NK cells

2012 • 260 citations

Opsonization of Apoptotic Cells by Autologous iC3b Facilitates Clearance by Immature Dendritic Cells, Down-regulates DR and CD86, and Up-regulates CC Chemokine Receptor 7

2002 • 260 citations

Mouse <scp>TIGIT</scp> inhibits <scp>NK</scp>‐cell cytotoxicity upon interaction with <scp>PVR</scp>

2013 • 219 citations

Fap2 of Fusobacterium nucleatum Is a Galactose-Inhibitable Adhesin Involved in Coaggregation, Cell Adhesion, and Preterm Birth

2015 • 205 citations

Fusobacterium nucleatumInduces Fetal Death in Mice via Stimulation of TLR4-Mediated Placental Inflammatory Response

2007 • 163 citations

FadA from Fusobacterium nucleatum Utilizes both Secreted and Nonsecreted Forms for Functional Oligomerization for Attachment and Invasion of Host Cells

2007 • 156 citations

Direct Recognition of Fusobacterium nucleatum by the NK Cell Natural Cytotoxicity Receptor NKp46 Aggravates Periodontal Disease

2012 • 113 citations

Identification of Oral Bacterial DNA in Synovial Fluid of Patients With Arthritis With Native and Failed Prosthetic Joints

2012 • 106 citations

Killer cell immunoglobulin‐like receptors on NK cells: the how, where and why

2007 • 94 citations

Colorectal Cancer: Looking for Answers in the Microbiota

2013 • 76 citations

Inhibitory NK Receptor Recognition of HLA-G: Regulation by Contact Residues and by Cell Specific Expression at the Fetal-Maternal Interface

2010 • 71 citations

Immune evasion by oncogenic proteins of acute myeloid leukemia

2014 • 56 citations

Virus-mediated inhibition of natural cytotoxicity receptor recognition

2012 • 49 citations

The use of mycobacterial adjuvant-based agents for immunotherapy of cancer

2008 • 49 citations

The search for disease-associated compositional shifts in bowel bacterial communities of humans

2008 • 43 citations

Fusobacterium nucleatum Activates the Immune Response through Retinoic Acid–Inducible Gene I

2013 • 22 citations

Methods to Identify and Characterize Different NK Cell Receptors and Their Ligands

2009 • 8 citations

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Binding of the Fap2 Protein of Fusobacterium nucleatum to Human Inhibitory Receptor TIGIT… (2015) – Immunity | Metascience Observatory Explorer