Brainstem noradrenergic control of nociception is abnormal in the spontaneously hypertensive rat

Quantitative assessment of tactile allodynia in the rat paw

1994 • 6,953 citations

The formalin test: an evaluation of the method

1992 • 2,414 citations

Distribution and targeting of a mu-opioid receptor (MOR1) in brain and spinal cord

1995 • 635 citations

Interactions between cardiovascular and pain regulatory systems

1984 • 410 citations

Altered pain perception in hypertensive humans

1980 • 298 citations

Pain sensitivity and opioid activity in genetically and experimentally hypertensive rats

1980 • 211 citations

The relationship between pain sensitivity and blood pressure in normotensives

1992 • 208 citations

Factors influencing the altered pain perception in the spontaneously hypertensive rat

1982 • 191 citations

Persistent cardiovascular and behavioral nociceptive responses to subcutaneous formalin require peripheral nerve input

1995 • 175 citations

Arterial hypertension is associated with hypalgesia in humans.

1988 • 171 citations

The function of noradrenergic neurons in mediating antinociception induced by electrical stimulation of the locus coeruleus in two different sources of Sprague-Dawley rats

1993 • 169 citations

Central noradrenergic lesioning using anti-DBH-saporin: anatomical findings

1996 • 159 citations

Quantitative characterization of ceruleospinal inhibition of nociceptive transmission in the rat

1986 • 152 citations

Locus coeruleus complex: elicitation of a pressor response and a brain stem region necessary for its occurence

1976 • 151 citations

Naloxone reversible decrease in pain sensitivity in young and adult spontaneously hypertensive rats

1981 • 132 citations

Anatomical evidence for genetic differences in the innervation of the rat spinal cord by noradrenergic locus coeruleus neurons

1992 • 130 citations

Differential effects of neurotoxic destruction of descending noradrenergic pathways on acute and persistent nociceptive processing

1999 • 128 citations

A novel long-latency response of locus coeruleus neurons to noxious stimuli: mediation by peripheral C-fibers

1994 • 108 citations

Hemodynamic stress activates locus coeruleus neurons of unanesthetized rats

1993 • 66 citations

Activation of Coeruleospinal Noradrenergic Inhibitory Controls during Withdrawal from Morphine in the Rat

1998 • 61 citations

Genetic differences in morphine sensitivity, tolerance and withdrawal in rats

1998 • 58 citations

Naloxone reverses the antinociceptive action of clonidine in spontaneously hypertensive rats

1985 • 36 citations

Exaggerated cardiovascular and behavioral nociceptive responses to subcutaneous formalin in the spontaneously hypertensive rat

1995 • 32 citations

Age, strain and anesthetic dependent differences in the nociceptive responses produced by i.v. 5-HT in the rat

1992 • 17 citations