The pineal, a tranquillizing organ?

The Relaxation Response

1974 • 2,339 citations

MTP international review of science

1973 • 761 citations

Visual pathways and the central neural control of a circadian rhythm in pineal serotonin N-acetyltransferase activity

1974 • 682 citations

On the effect of melatonin upon human brain. Its possible therapeutic implications

1971 • 320 citations

Daily Rhythm in Human Urinary Melatonin

1975 • 262 citations

The functions of sleep

1973 • 238 citations

Acute Pharmacology of Melatonin

1967 • 216 citations

Comparative Physiology: Pineal Gland

1973 • 213 citations

Nocturnal Elevation of Plasma Melatonin and Urinary 5-Hydroxyindoleacetic Acid in Young Men: Attempts at Modification by Brief Changes in Environmental Lighting and Sleep and by Autonomic Drugs

1976 • 201 citations

Pineal Function in Sparrows: Circadian Rhythms and Body Temperature

1971 • 191 citations

The role of suprachiasmatic nuclei of the hypothalamus in the production of circadian rhythm

1976 • 176 citations

Differential localization of N-acetylated indolealkylamines in CNS and the Harderian gland using immunohistology

1976 • 174 citations

Pineal Control of a Seasonal Reproductive Rhythm in Male Golden Hamsters Exposed to Natural Daylight and Temperature

1973 • 165 citations

Circannual reproductive rhythms in mammals related to photoperiod and pineal function: a review.

1974 • 165 citations

Radioimmunoassay of Melatonin: Human Serum and Cerebrospinal Fluid

1977 • 165 citations

Melatonin: Effects on the Circadian Locomotor Rhythm of Sparrows

1976 • 163 citations

Melatonin: Daily Cycle in Plasma and Cerebrospinal Fluid of Calves

1977 • 157 citations

Adrenergic-adenosine 3',5'-monophosphate regulation of serotonin N-acetyltransferase activity and the temporal relationship of serotonin N-acetyltransferase activity synthesis of 3H-N-acetylserotonin and 3H-melatonin in the cultured rat pineal gland.

1973 • 150 citations

Sleep induced by the administration of melatonin (5-methoxy-N-acetyltryptamine) to the hypothalamus in unrestrained cats

1964 • 146 citations

Presence of Melatonin in Plasma and Urine of Pinealectomized Rats¹

1976 • 145 citations

Hormones and Brain Function

1973 • 141 citations

Hydroxyindole—O—Methyl Transferases in Rat Pineal, Retina and Harderian Gland

1972 • 135 citations

Visual Pathway Mediating Pineal Response to Environmental Light

1967 • 133 citations

Urinary melatonin rhythms during sleep deprivation in depressed patients and normals

1977 • 132 citations

Growth Hormone Regulation by Melatonin and Serotonin

1973 • 123 citations

Central Control of the Pineal Gland: Visual Pathways

1968 • 118 citations

Structure and innervation of the pineal gland of the rabbit, oryctolagus cuniculus (L.)

1973 • 113 citations

Slow-wave sleep induced in cats by extremely small amounts of synthetic and pineal vasotocin injected into the third ventricle of the brain

1977 • 110 citations

The ultrastructure of the rabbit pineal gland after sympathectomy, parasympathectomy, continuous illumination, and continuous darkness

1975 • 99 citations

Immunohistochemical localization of melatonin in the rat Harderian gland.

1976 • 97 citations

Effet de la pine´alectomie sur lese´tats et rythmes de sommeil du rat maˆle

1974 • 96 citations

Serotonin, noradrenaline, dopamine metabolites in transcendental meditation-technique

1976 • 96 citations

Structure and innervation of the pineal gland of the rabbit, Oryctolagus cuniculus (L.)

1975 • 87 citations

Experimental Modification of the Rat Pineal's Content of Serotonin and Related Indole Amines

1962 • 85 citations

Serotonin Content of the Pineal Glands of Man and Monkey

1960 • 83 citations

Differential effects of peripheral and central anosmia producing techniques on spontaneous behavior patterns

1974 • 80 citations

Effect of Melatonin and Other Pineal Indoles on Adrenal Enlargement Produced in Male and Female Mice by Pinealectomy, Unilateral Adrenalectomy, Castration, and Cold Stress

1972 • 79 citations

Growth Hormone Responses to Melatonin in Man

1974 • 78 citations

Experimental hypertension in pinealectomized rats

1967 • 77 citations

Pineal Methoxyindoles: New Evidence Concerning Their Function in the Control of Pineal-Mediated Changes in the Reproductive Physiology of Male Golden Hamsters

1975 • 71 citations

Pineal antigonadotrophic substances: Polypeptides and indoles

1977 • 69 citations

Influence of pineal gland on the growth and spread of melanoma in the hamster.

1967 • 68 citations

Exploratory behavior and spontaneous alternation in blind and anosmic rats.

1969 • 66 citations

Modifications of thyroid activity by melatonin

1963 • 64 citations

Changes in the Electrical Activity of the Brain Following Pinealectomy

1969 • 61 citations

THE GROWTH AND SPREAD OF WALKER 256 CARCINOMA IN PINEALECTOMIZED RATS.

1963 • 56 citations

The Effect of Pineal Grafts, Pinealectomy, and Denervation of the Pineal Gland on the Reproductive Organs of Male Hamsters

1967 • 55 citations

Parasympathetic innervation of the rabbit pineal gland

1973 • 55 citations

Correlations of Melatonin Content in Pineal Gland, Blood, and Brain of Some Birds and Mammals

1976 • 51 citations

Localization of a sheep pineal antigonadotropin

1973 • 50 citations

Structure and innervation of the pineal gland of the rabbit,Oryctolagus cuniculus (L.)

1973 • 47 citations

Core temperature in the female rat: effect of pinealectomy or altered lighting

1976 • 47 citations

PERSISTENT RHYTHMS OF PINEAL AND SERUM MELATONIN IN COCKERELS IN CONTINUOUS DARKNESS

1974 • 46 citations

THE METABOLISM OF [1,2-3H]17α-METHYLTESTOSTERONE IN HUMAN SUBJECTS

1967 • 46 citations

Flow of Blood to the Pineal Body of the Rat

1964 • 45 citations

Studies with Pinealectomized Rats

1970 • 43 citations

Nature and the time course of seizures associated with surgical removal of the pineal gland from parathyroidectomized rats

1973 • 40 citations

Electron microscopy of the rabbit pineal organ in vitro

1976 • 40 citations

EFFECT OF MELATONIN AND 5-HYDROXYTRYPTAMINE ON ALDOSTERONE AND CORTICOSTERONE PRODUCTION BY ADRENAL GLANDS OF NORMAL AND HYPOPHYSECTOMIZED RATS

1967 • 37 citations

New Horizons of Pineal Research

1976 • 35 citations

Free Thyroxin Index in Normal, Melatonin-Treated and Blind Hamsters

1977 • 35 citations

Diurnal variations in number of Golgi-dense core vesicles in light pinealocytes of the rabbit

1976 • 34 citations

Effect of chronic pinealectomy on adrenocortical hormone secretion rates in normal and hypertensive rats

1967 • 33 citations

Effects of the Pineal Gland Upon the Hair Cycles in Mice

1966 • 32 citations

EFFECTS OF PHOTOPERIOD AND MELATONIN ON REPRODUCTION IN THE SYRIAN HAMSTER

1976 • 31 citations

Muscular spasms and death in thyroparathyroidectomized rats subjected to pinealectomy

1972 • 31 citations

Role of the Pineal Gland in Growth Restraint of Adult Male Rats by Light and Smell Deprivation

1971 • 27 citations

EVIDENCE FOR THE EXISTENCE OF A PINEAL-ADRENAL AND A PINEAL-THYROID AXIS

1972 • 27 citations

Characterization and partial purification of a substance in the pineal gland which inhibits cell multiplication in vitro

1976 • 27 citations

Melatonin-induced changes in the sensory activation of acute epileptic foci

1976 • 25 citations

Effects of Pinealectomy on Adrenal Functionin Vivoandin Vitroin Female Rats

1976 • 24 citations

POSTSYNAPTIC ADRENERGIC‐CYCLIC AMP CONTROL OF THE SEROTONIN CONTENT OF CULTURED RAT PINEAL GLANDS

1973 • 24 citations

EFFECTS OF THE PINEAL GLAND IN UNILATERALLY ADRENALECTOMIZED RATS

1972 • 22 citations

EFFECTS OF PINEALECTOMY, CONSTANT LIGHT AND DARKNESS ON GROWTH HORMONE LEVELS IN THE PITUITARY AND PLASMA OF THE RAT

1972 • 21 citations

Influence of the pineal on wound healing

1975 • 19 citations

Effects of melatonin on the photosensitive epilepsy of the baboon, Papio papio

1976 • 19 citations

A pharmacological and autoradiographic study on the ultrastructural localization of indoleamine synthesis in the rabbit pineal gland

1977 • 19 citations

The influence of some sympatholytic, parasympatholytic and serotonin-synthesis-inhibiting agents on the ultrastructure of the rabbit pineal organ

1976 • 18 citations

Electron microscopic evidence of glycogen storage in the dark pinealocytes of the rabbit pineal gland

1977 • 18 citations

Olfactory bulb removal results in elevated spontaneous locomotor activity in mice

1976 • 17 citations

The effect of melatonin on the biosynthesis of corticosteroids in beef adrenal preparations in vitro

1977 • 15 citations

RADIOMETRIC ASSAY OF TOTAL TRYPTOPHAN HYDROXYLATION BY INTACT CULTURED PINEAL GLANDS

1974 • 15 citations

Endocrine effects of the pineal gland and neutralization of circulating melatonin and N-acetylserotonin

1977 • 15 citations

Effects of melatonin administration and pinealectomy on the electroencephalogram of the chicken () brain

1976 • 15 citations

Blindness-induced hyperactivity in several strains of mice

1975 • 11 citations

Effects of an Aldosterone Antagonist, Spironolactone, on Pinealectomized Rats

1971 • 11 citations

The maturation of melatonin synthesis in the lateral eyes of the mouse

1974 • 8 citations

The effect of pinealectomy on adrenocortical rhytmhm in the blinded rat

1974 • 8 citations

Effect of drugs which inhibit tryptophan hydroxylase or dopamine-β-hydroxylase on pinealectomy-induced seizures in parathyroidectomized rats

1975 • 8 citations

Blindness-induced hyperactivity in several strains of mice

1975 • 7 citations

[The action in vitro of melatonine on hormonosynthesis in the adrenal cortex of the rat].

1970 • 5 citations

Hyperactivity in the blind-anosmic female rat: Role of the pineal gland

1977 • 4 citations