High frequencies of α-thalassaemia are the result of natural selection by malaria

The Genetics of Human Populations.

1972 • 1,645 citations

The Genetics of Human Populations

1972 • 1,252 citations

Protection Afforded by Sickle-cell Trait Against Subtertian Malarial Infection

1954 • 1,228 citations

Complete nucleotide sequences of the T24 human bladder carcinoma oncogene and its normal homologue

1983 • 1,028 citations

Polymorphic DNA region adjacent to the 5' end of the human insulin gene.

1981 • 910 citations

THE MUTATION AND POLYMORPHISM OF THE HUMAN β-GLOBIN GENE AND ITS SURROUNDING DNA

1984 • 404 citations

THE RATE OF MUTATION OF HUMAN GENES

2010 • 373 citations

Construction of linkage maps with DNA markers for human chromosomes

1985 • 325 citations

Cellular mechanism for the protective effect of haemoglobin S against P. falciparum malaria

1978 • 319 citations

The distribution of the sickle-cell trait in East Africa and elsewhere, and its apparent relationship to the incidence of subtertian malaria

1954 • 315 citations

Erythrocytic mechanism of sickle cell resistance to malaria.

1978 • 296 citations

Two different molecular organizations account for the single alpha-globin gene of the alpha-thalassemia-2 genotype.

1980 • 274 citations

A Prehistory of Australia, New Guinea and Sahul.

1984 • 258 citations

Triplicated alpha-globin loci in humans.

1980 • 241 citations

Genetic Control of some Serum Proteins in Normal Humans

1955 • 233 citations

Population Structure and Genetic Disorders

1982 • 231 citations

Man's conquest of the Pacific

1979 • 216 citations

A novel α-globin gene arrangement in man

1980 • 159 citations

Independent recombination events between the duplicated human α globin genes; implications for their concerted evolution

1984 • 157 citations

Population genetics of haemoglobin variants, thalassaemia and glucose-6-phosphate dehydrogenase deficiency, with particular reference to the malaria hypothesis.

1966 • 151 citations

The First Americans: Origins, Affinities, and Adaptations.

1980 • 122 citations

THE INTERACTION OF MALARIA PARASITES WITH RED BLOOD CELLS

1982 • 118 citations

Gamma thalassemia resulting from the deletion of a gamma-globin gene.

1983 • 91 citations

Report of the committee on the genetic constitution of chromosomes 1 and 2

1987 • 84 citations

Melanesians and Polynesians share a unique alpha-thalassemia mutation.

1985 • 77 citations

Linkage analysis of myotonic dystrophy and sequences on chromosome 19 using a cloned complement 3 gene probe.

1983 • 74 citations

A NEW TRIPLICATED α‐GLOBIN GENE ARRANGEMENT IN MAN

1981 • 66 citations

Studies on the epidemiology of malaria in New Guinea

1960 • 64 citations

α THALASSAEMIA IN PAPUA NEW GUINEA

1984 • 62 citations

Recombination within the human embryonic ζ-globin locus: A common ζ-ζ chromosome produced by gene conversion of the ψζ gene

1985 • 59 citations

Plasmodium falciparum in vitro: diminished growth in hemoglobin H disease erythrocytes

1985 • 56 citations

The Gerbich Blood Group System, Especially in Melanesians

1972 • 55 citations

The First Americans: Origins, Affinites, and Adaptations

1979 • 51 citations

A COMPARISON OF THE GENETIC INFRASTRUCTURE OF THE YE'CUANA AND THE YANOMAMA: A LIKELIHOOD ANALYSIS OF GENOTYPIC VARIATION AMONG POPULATIONS

1978 • 47 citations

A novel rearrangement of the human βlike globin gene cluster

1981 • 44 citations

RELATIVE ROLES OF GENETIC FACTORS, DIETARY DEFICIENCY, AND INFECTION IN ANAEMIA IN VANUATU, SOUTH-WEST PACIFIC

1985 • 40 citations

Mitotic chiasmata, gene density, and oncogenes

1985 • 34 citations

The positions of three restriction fragment length polymorphisms on chromosome 4 relative to known genetic markers

1984 • 33 citations

Report of the committee on the genetic constitution of chromosomes 1 and 2

1985 • 33 citations

Extremely high frequencies of alpha-globin gene deletion in Madang and on Kar Kar Island, Papua New Guinea.

1985 • 30 citations

Detection of Alpha Thalassaemia in Negro Infants

1980 • 29 citations

The depolution of the new hebrides and other parts of Melanesia

1926 • 25 citations

Studies on the epidemiology of malaria in New Guinea Part IV. Unstable highland malaria—The clinical picture

1960 • 24 citations

α Globin gene rearrangements in polynesians are not associated with malaria

1985 • 23 citations

A population genetic survey of the haptoglobin polymorphism in Melanesians by DNA analysis.

1986 • 18 citations

On the Occurrence and Prevalence of Diseases in British New Guinea

1915 • 18 citations

Parasites of man in Niugini

1971 • 14 citations

THE EPIDEMIOLOGY OF MALARIA IN THE SOUTHWEST PACIFIC: CHANGES ASSOCIATED WITH INCREASING EUROPEAN CONTACT

1956 • 10 citations

IV. Parasitological Observations on Malaria in Natives and Troops, and on Filariasis in Natives

1947 • 10 citations

Epidemiology of Malaria in the New Hebrides

1979 • 8 citations

The geographical distribution of Malaria in the South‐West Pacific

1955 • 7 citations

Is the doubly deleted alpha-thalassemia gene a "fugitive" allele?

1981 • 6 citations

Anopheles and Malaria at Aneityum, New Hebrides

1954 • 4 citations