m-AMSA and PALA: Two new agents in cancer chemotherapy

Cis-diamminedichloroplatinum (II)

1977 • 424 citations

Aspartate Transcarbamylase

1971 • 422 citations

Stable mutants of mammalian cells that overproduce the first three enzymes of pyrimidine nucleotide biosynthesis

1976 • 228 citations

The Use of Drugs in Combination for the Treatment of Cancer

1973 • 193 citations

Evaluation of single agents and combinations of chemotherapeutic agents in mouse colon carcinomas

1977 • 184 citations

The experimental antitumour properties of three congeners of the acridylmethanesulphonanilide (AMSA) series

1974 • 155 citations

In vivo characteristics of resistance and cross-resistance of an adriamycin-resistant subline of P388 leukemia.

1978 • 135 citations

VM 26 and VP 16–213: A comparative analysis

1977 • 122 citations

DNA-binding characteristics of acridinylmethanesulphonanilide drugs: Comparison with antitumour properties

1976 • 114 citations

Chemotherapy of human colon cancer xenografts in athymic nude mice

1977 • 107 citations

Effects of N-(phosphonacetyl)-L-aspartate on murine tumors and normal tissues in vivo and in vitro and the relationship of sensitivity to rate of proliferation and level of aspartate transcarbamylase.

1978 • 74 citations

Phase 1 clinical investigation of 4'-(9-acridinylamino)methanesulfon-m-anisidide (NSC 249992), a new acridine derivative.

1978 • 71 citations

The chemotherapy of Hodgkin's disease.Past experiences and future directions

1978 • 60 citations

Cell-Cycle-Specific Chromosome Damage Following Treatment of Cultured Chinese Hamster Cells With 4′-[(9-Acridinyl-amino] methanesulphon-m-anisidide-HCl2

1978 • 56 citations

Reversal of toxicity and antitumor activity of N-(phosphonacetyl)-L-aspartate by uridine or carbamyl-DL-aspartate in vivo

1977 • 55 citations

The pharmacologic disposition of 4'-(9-acridinylamino)methanesulfon-m-anisidide in mice and rats.

1977 • 50 citations

Inhibition by N-(Phosphonacetyl)-l-Aspartate of Aspartate Transcarbamylase Activity and Drug-induced Cell Proliferation in Mice

1974 • 49 citations

Clinical trials in cancer chemotherapy

1977 • 49 citations

Induction of limited DNA damage by the antitumor agent Cain's acridine.

1978 • 46 citations

Interaction of 4'-(9-acridinylamino)methanesulfon-m-anisidide with DNA and inhibition of oncornavirus reverse transcriptase and cellular nucleic acid polymerases.

1978 • 44 citations

Phase I study of methanesulfonamide, N-[4-(9-acridinylamino)-3-methoxyphenyl]-(m-AMSA) using a single-dose schedule.

1978 • 41 citations

Mechanisms of sensitivity or resistance of murine tumors to N-(phosphonacetyl)-L-aspartate (PALA).

1979 • 36 citations

The clinical evaluation of analogues

1978 • 36 citations

Kinetic Response of Cultured Chinese Hamster Cells to Treatment With 4′-[(9-Acridinyl-amino] methanesulphon-m-anisidide-HCl2

1978 • 33 citations

Enzymes in pyrimidine biosynthesis

1971 • 32 citations

Chemotherapy of testicular cancer: from palliation to curative adjuvant therapy.

1979 • 29 citations

Comparative Activties of Aspartate Transcarbamylase in Various Tissues of the Rat.

1967 • 22 citations

Whatever happened to NSC--? An analysis of clinical results of discontinued anticancer agents.

1977 • 19 citations

Selective Localization of 4-(9-Acridinylamino)-methanesulfon-m-anisididein B 16 Melanoma

1978 • 15 citations

An assessment of the immunosuppressive activity of the anti-tumour compound 4′-[(9-acridinyl)amino]methanesulphon-m-anisidide (m-AMSA)

1974 • 12 citations

Anthracycline derivatives in new drug development programs.

1979 • 11 citations

Pyrimidine nucleosides enhance the anti-cancer activity of fu and augment its incorporation into nuclear tna. Abstr.

1978 • 10 citations

ANTIVIRAL ACTIVITIES OF 4′‐(9‐ACRIDINYLAMINO)‐METHANESULFON‐M‐ANISIDE (SN11841)

1977 • 9 citations

An enzymatic technique for measuring N-phosphonacetyl-L-aspartic acid in tissues.

1978 • 7 citations

Oral Absorption and Selective Tissue Localization of 4’-(9-Acridinylamino)-methanesulfon-m-anisidide

1978 • 6 citations

Determination of N-(Phosphonacetyl)-L-aspartic acid (PALA) in dog serum and urine by gas chromatography and selected lon monitoring.

1979 • 4 citations

Physiological disposition of pala in several species. Abstr.

1978 • 3 citations

Determination of N-(Phosphonacetyl)-L-aspartic acid (PALA) in dog serum and urine by gas chromatography and selected lon monitoring.

1979 • 1 citations

Deleted Work

1955 • 0 citations