Restricted maturation of antibody-binding characteristics for hapten-specific IgM-plaque-forming cells in mice

The clonal selection theory of acquired immunity

1959 • 2,008 citations

The clonal selection theory of acquired immunity

1959 • 1,576 citations

Variations in Affinities of Antibodies during the Immune Response^*

1964 • 1,078 citations

The somatic generation of immune recognition

1971 • 974 citations

Cell Selection by Antigen in the Immune Response

1969 • 594 citations

CELLULAR LOCALIZATION OF IMMUNOGLOBULINS WITH DIFFERENT ALLOTYPIC SPECIFICITIES IN RABBIT LYMPHOID TISSUES

1965 • 444 citations

Mouse myeloma proteins with antihapten antibody activity. Protein produced by plasma cell tumor MOPC-315

1968 • 339 citations

IMMUNOLOGICAL SPECIFICITY OF DELAYED AND IMMEDIATE HYPERSENSITIVITY REACTIONS

1962 • 229 citations

Mechanism of Antibody Diversity: Germ Line Basis for Variability

1970 • 222 citations

RABBIT LYMPHOID CELLS DIFFERENTIATED WITH RESPECT TO α-, γ-, AND µ- HEAVY POLYPEPTIDE CHAINS AND TO ALLOTYPIC MARKERS A<scp>A</scp>1 AND A<scp>A</scp>2

1966 • 212 citations

STUDIES ON THE REGULATION OF AVIDITY AT THE LEVEL OF THE SINGLE ANTIBODY-FORMING CELL

1970 • 185 citations

STUDIES ON THE CONTROL OF ANTIBODY SYNTHESIS

1968 • 159 citations

SEQUENTIAL CHANGES IN THE RELATIVE AFFINITY OF ANTIBODIES SYNTHESIZED DURING THE IMMUNE RESPONSE

1967 • 122 citations

RECEPTORS ON IMMUNOCOMPETENT CELLS

1972 • 118 citations

SPECIFICITY OF CELLULAR IMMUNE RESPONSES

1968 • 100 citations

Haptenated bacteriophage in the assay of antibody quantity and affinity: Maturation of an immune response

1970 • 90 citations

The Effect of Antigen Dose and Time after Immunization on the Amount and Affinity of Anti-Hapten Antibody

1968 • 88 citations

Characterization of the antibody response to type 3 pneumococcal polysaccharide at the cellular level. 3. Studies on the average avidity of the antibody produced by specific plaque-forming cells.

1971 • 71 citations

The immune response to influenza virus. 3. Changes in the avidity and specificity of early IgM and IgG antibodies.

1968 • 60 citations

Antibody formation. V. The avidity of gamma-M and gamma-G guinea pig antibodies to bacteriophage phi-x 174.

1966 • 41 citations

Characterization of the Antibody Response to Type III Pneumococcal Polysaccharide at the Cellular Level

1971 • 39 citations

Inactivation of Bacteriophage T4, of Poly-D-Alanyl Bacteriophage and of Penicilloyl Bacteriophage by Immunospecifically Isolated IgM and IgG Antibodies

1969 • 35 citations

Purification and Analysis of “Monofocal” Antibody

1971 • 34 citations

The Use of Concanavalin A for Distinguishing IgM from IgG Antibody-Producing Cells

1969 • 29 citations

Antibody Formation

1966 • 22 citations

Comparative Sensitivities of the Hemolytic Plaque-in-Agar and Microchamber Assays for Detection of Rabbit Immune Cells

1968 • 21 citations

Duplicate Plating of Immune Cell Products: Analysis of Globulin Class Secretion by Single Cells

1970 • 10 citations

Secretion of Monospecific Anti-Hapten IgG Antibodies by Rabbit Immunocytes

1971 • 7 citations

Comet Plaques: Evidence for Storage of Low Efficiency Hemolysins by Indirect Plaque-Forming Cells

1970 • 1 citations