Neutralizing Antibodies Have Limited Effects on the Control of Established HIV-1 Infection In Vivo

Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection

1995 • 4,310 citations

HIV-1 Dynamics in Vivo: Virion Clearance Rate, Infected Cell Life-Span, and Viral Generation Time

1996 • 3,496 citations

HIV Population Dynamics in Vivo: Implications for Genetic Variation, Pathogenesis, and Therapy

1995 • 1,997 citations

Human monoclonal antibody 2G12 defines a distinctive neutralization epitope on the gp120 glycoprotein of human immunodeficiency virus type 1

1996 • 1,111 citations

Efficient Neutralization of Primary Isolates of HIV-1 by a Recombinant Human Monoclonal Antibody

1994 • 1,106 citations

A conserved neutralizing epitope on gp41 of human immunodeficiency virus type 1

1993 • 1,005 citations

Dual Infection of the Central Nervous System by AIDS Viruses with Distinct Cellular Tropisms

1987 • 831 citations

A large array of human monoclonal antibodies to type 1 human immunodeficiency virus from combinatorial libraries of asymptomatic seropositive individuals.

1991 • 662 citations

Dissociation of gp120 from HIV-1 Virions Induced by Soluble CD4

1990 • 598 citations

Medicine and the Law

1987 • 541 citations

Recognition properties of a panel of human recombinant Fab fragments to the CD4 binding site of gp120 that show differing abilities to neutralize human immunodeficiency virus type 1

1994 • 457 citations

Rapid development of isolate-specific neutralizing antibodies after primary HIV-1 infection and consequent emergence of virus variants which resist neutralization by autologous sera

1990 • 416 citations

Human immunodeficiency virus type 1 neutralization is determined by epitope exposure on the gp120 oligomer.

1995 • 334 citations

Neutralizing Antibody Responses to Human Immunodeficiency Virus Type 1 in Primary Infection and Long‐Term‐Nonprogressive Infection

1997 • 327 citations

Human Immunodeficiency Virus Infection of Human-PBL-SCID Mice

1991 • 277 citations

Passive immunization with a human monoclonal antibody protects hu-PBL-SCID mice against challenge by primary isolates of HIV-1

1997 • 262 citations

Human Immunodeficiency Virus Replication and Genotypic Resistance in Blood and Lymph Nodes after a Year of Potent Antiretroviral Therapy

1998 • 216 citations

Rapid Loss of CD4 ⁺ T Cells in Human-PBL-SCID Mice by Noncytopathic HIV Isolates

1993 • 189 citations

Neutralization of Human Immunodeficiency Virus Type 1 by Antibody to gp120 Is Determined Primarily by Occupancy of Sites on the Virion Irrespective of Epitope Specificity

1998 • 188 citations

Passive Immunization of Newborn Rhesus Macaques Prevents Oral Simian Immunodeficiency Virus Infection

1998 • 171 citations

HIV-1 neutralization: the consequences of viral adaptation to growth on transformed T cells.

1995 • 170 citations

Distinct biological and serological properties of human immunodeficiency viruses from the brain

1988 • 163 citations

Protection against HIV-1 infection in hu-PBL-SCID mice by passive immunization with a neutralizing human monoclonal antibody against the gp120 CD4-binding site

1995 • 154 citations

Evaluation of Monoclonal Antibodies to Human Immunodeficiency Virus Type 1 Primary Isolates by Neutralization Assays: Performance Criteria for Selecting Candidate Antibodies for Clinical Trials

1997 • 149 citations

Autologous HIV-1 Neutralizing Antibodies

1992 • 147 citations

The antibody response in HIV-1 infection.

1997 • 122 citations

hu-PBL-SCID mice can be protected from HIV-1 infection by passive transfer of monoclonal antibody to the principal neutralizing determinant of envelope gp120

1993 • 96 citations

Neutralization of Multiple HIV-1 Isolates from a Single Subject by Autologous Sequential Sera

1990 • 87 citations

Human immunodeficiency virus type 1 mutants that escape neutralization by human monoclonal antibody IgG1b12. off

1997 • 83 citations

Antibody Neutralization-Resistant Primary Isolates of Human Immunodeficiency Virus Type 1

1998 • 72 citations

Pre- and Postexposure Protection against Human Immunodeficiency Virus Type 1 Infection Mediated by a Monoclonal Antibody

1995 • 68 citations

HIV-1 dynamics in vivo.

1995 • 59 citations

Humanization and molecular modeling of the anti-CD4 monoclonal antibody, OKT4A.

1996 • 50 citations

Passive Immunization with a Human Immunodeficiency Virus Type 1-Neutralizing Monoclonal Antibody in Hu-PBL-SCID Mice: Isolation of a Neutralization Escape Variant

1998 • 46 citations

Effect of anti‐V3 antibodies on cell‐free and cell‐to‐cell human immunodeficiency virus transmission

1995 • 28 citations

thy/liv‐SCID‐hu Mice: A System for Investigating the In Vivo Effects of Multidrug Therapy on Plasma Viremia and Human Immunodeficiency Virus Replication in Lymphoid Tissues

1998 • 21 citations

Chemokine Receptor Polymorphism and Autologous Neutralizing Antibody Response in Long-Term HIV-1 Infection

1998 • 11 citations