Mobilizing Patients in the Intensive Care Unit

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1960 • 10,428 citations

Daily Interruption of Sedative Infusions in Critically Ill Patients Undergoing Mechanical Ventilation

2000 • 2,838 citations

One-Year Outcomes in Survivors of the Acute Respiratory Distress Syndrome

2003 • 2,141 citations

Paresis Acquired in the Intensive Care Unit<SUBTITLE>A Prospective Multicenter Study</SUBTITLE>

2002 • 1,389 citations

Early intensive care unit mobility therapy in the treatment of acute respiratory failure*

2008 • 1,269 citations

PGC-1α protects skeletal muscle from atrophy by suppressing FoxO3 action and atrophy-specific gene transcription

2006 • 926 citations

Early activity is feasible and safe in respiratory failure patients*

2006 • 835 citations

Two-Year Cognitive, Emotional, and Quality-of-Life Outcomes in Acute Respiratory Distress Syndrome

2004 • 707 citations

Physiotherapy for adult patients with critical illness: recommendations of the European Respiratory Society and European Society of Intensive Care Medicine Task Force on Physiotherapy for Critically Ill Patients

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The Long-term Psychological Effects of Daily Sedative Interruption on Critically Ill Patients

2003 • 641 citations

Neuromuscular dysfunction acquired in critical illness: a systematic review

2007 • 600 citations

Quality of life in adult survivors of critical illness: A systematic review of the literature

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Prolonged bed rest decreases skeletal muscle and whole body protein synthesis

1996 • 483 citations

Physical Inactivity Rapidly Induces Insulin Resistance and Microvascular Dysfunction in Healthy Volunteers

2007 • 439 citations

Reduced Quality of Life in Survivors of Acute Respiratory Distress Syndrome Compared With Critically Ill Control Patients

1999 • 431 citations

Risk factors for the development of polyneuropathy and myopathy in critically ill patients

2001 • 357 citations

Impact of Intensive Insulin Therapy on Neuromuscular Complications and Ventilator Dependency in the Medical Intensive Care Unit

2006 • 353 citations

Lower limb skeletal muscle function after 6 wk of bed rest

1997 • 343 citations

Quality of life after acute respiratory distress syndrome: a meta-analysis

2006 • 331 citations

An overview of the issues: physiological effects of bed rest and restricted physical activity

1997 • 311 citations

Patients with respiratory failure increase ambulation after transfer to an intensive care unit where early activity is a priority

2008 • 272 citations

Effects of Physical Training on Functional Status in Patients With Prolonged Mechanical Ventilation

2006 • 267 citations

Sedation algorithm in critically ill patients without acute brain injury

2005 • 245 citations

Pulmonary Function and Health-related Quality of Life in Survivors of Acute Respiratory Distress Syndrome

2003 • 240 citations

Rehabilitation of patients admitted to a respiratory intensive care unit

1998 • 229 citations

Health-related Quality of Life after Acute Lung Injury

1997 • 219 citations

Metabolic Consequences of Muscle Disuse Atrophy

2005 • 187 citations

Transforming ICU Culture to Facilitate Early Mobility

2007 • 182 citations

Impact of whole-body rehabilitation in patients receiving chronic mechanical ventilation

2005 • 175 citations

THE EVIL SEQUELAE OF COMPLETE BED REST

1944 • 174 citations

Pulmonary function and health-related quality of life in a sample of long-term survivors of the acute respiratory distress syndrome

2000 • 171 citations

Epidemiology of sedation and sedation adequacy for mechanically ventilated patients in a medical and surgical intensive care unit*

2007 • 160 citations

The safety of mobilisation and its effect on haemodynamic and respiratory status of intensive care patients

2004 • 137 citations

Inactivity and Inflammation in the Critically Ill Patient

2007 • 107 citations

Acute neuromuscular weakness in the intensive care unit

2006 • 94 citations

Activity in the Chronically Critically Ill

2005 • 88 citations

Mechanisms for decreased exercise capacity after bed rest in normal middle-aged men

1983 • 82 citations

Systemic inflammatory response syndrome increases immobility-induced neuromuscular weakness*

2008 • 69 citations

Intensive care unit exposures for long-term outcomes research: Development and description of exposures for 150 patients with acute lung injury

2007 • 58 citations

The role of future longitudinal studies in ICU survivors: understanding determinants and pathophysiology of weakness and neuromuscular dysfunction

2007 • 40 citations

Neuromuscular Sequelae in Survivors of Acute Lung Injury

2006 • 35 citations

A Method for Augmenting Ventilation During Ambulation

1972 • 31 citations

Early Ambulation of Patients Requiring Ventilatory Assistance

1975 • 25 citations

THE ABUSE OF REST IN BED IN ORTHOPEDIC SURGERY

1944 • 21 citations

The neurological examination in the assessment of polyneuropathy in mechanically ventilated patients

1997 • 20 citations

Disabling Effects of Inactivity and Importance of Physical Conditioning

1990 • 16 citations