Neurocognitive Assessment in the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) Project Schizophrenia Trial: Development, Methodology, and Rationale

What are the functional consequences of neurocognitive deficits in schizophrenia?

1996 • 3,505 citations

Wisconsin Card Sorting Test Manual – Revised and Expanded

1981 • 2,973 citations

Neurocognitive Deficits and Functional Outcome in Schizophrenia: Are We Measuring the "Right Stuff"?

2000 • 2,955 citations

Neurocognitive deficit in schizophrenia: A quantitative review of the evidence.

1998 • 2,422 citations

Neurocognitive deficit in schizophrenia: A quantitative review of the evidence.

1998 • 2,270 citations

Society for Neuroscience Abstracts

1997 • 1,445 citations

The hopkins verbal learning test: Development of a new memory test with six equivalent forms

1991 • 1,237 citations

Information Processing and Attentional Functioning in the Developmental Course of Schizophrenic Disorders

1984 • 1,159 citations

Neuropsychological Function in Schizophrenia

1991 • 1,158 citations

Neuropsychological Deficits in Neuroleptic Naive Patients With First-Episode Schizophrenia

1994 • 1,099 citations

The Effects of Clozapine, Risperidone, and Olanzapine on Cognitive Function in Schizophrenia

1999 • 1,012 citations

Neuropsychology of First-Episode Schizophrenia: Initial Characterization and Clinical Correlates

2000 • 922 citations

Auditory Working Memory and Wisconsin Card Sorting Test Performance in Schizophrenia

1997 • 810 citations

The Effects of Atypical Antipsychotic Drugs on Neurocognitive Impairment in Schizophrenia: A Review and Meta-analysis

1999 • 698 citations

The role of D1-dopamine receptor in working memory: local injections of dopamine antagonists into the prefrontal cortex of rhesus monkeys performing an oculomotor delayed-response task

1994 • 663 citations

The continuous performance test, identical pairs version (CPT-IP): I. new findings about sustained attention in normal families

1988 • 658 citations

The National Institute of Mental Health Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) Project: Schizophrenia Trial Design and Protocol Development

2003 • 634 citations

Development of Cognitive Instruments for Use in Clinical Trials of Antidementia Drugs

1997 • 581 citations

Neurocognitive Effects of Clozapine, Olanzapine, Risperidone, and Haloperidol in Patients With Chronic Schizophrenia or Schizoaffective Disorder

2002 • 536 citations

Further Evidence for Dementia of the Prefrontal Type in Schizophrenia?

1987 • 524 citations

Emotion perception in schizophrenia: Specific deficit or further evidence of generalized poor performance?

1993 • 519 citations

Symptomatic and Neuropsychological Components of Defect States

1985 • 510 citations

Neuropsychological Change in Early Phase Schizophrenia During 12 Months of Treatment With Olanzapine, Risperidone, or Haloperidol

2000 • 478 citations

Emotion perception in schizophrenia: Specific deficit or further evidence of generalized poor performance?

1993 • 444 citations

Development of cognitive instruments for use in clinical trials of antidementia drugs: additions to the Alzheimer's Disease Assessment Scale that broaden its scope. The Alzheimer's Disease Cooperative Study.

1997 • 440 citations

Does risperidone improve verbal working memory in treatment-resistant schizophrenia?

1997 • 406 citations

Should Schizophrenia Be Treated as a Neurocognitive Disorder?

1999 • 404 citations

Improvement in cognitive functions and psychiatric symptoms in treatment-refractory schizophrenic patients receiving clozapine

1993 • 403 citations

Cognitive Deficits in Schizophrenia

1993 • 371 citations

Neuropsychological functioning of first-episode schizophreniform patients

1992 • 324 citations

The Case for Frontostriatal Dysfunction in Schizophrenia

1990 • 311 citations

Comparative Effect of Atypical and Conventional Antipsychotic Drugs on Neurocognition in First-Episode Psychosis: A Randomized, Double-Blind Trial of Olanzapine Versus Low Doses of Haloperidol

2004 • 310 citations

The comparative efficacy and long-term effect of clozapine treatment on neuropsychological test performance

1994 • 283 citations

Cognitive functioning and positive and negative symptoms in schizophrenia

1991 • 277 citations

Neuroleptics: Effects on Neuropsychological Function in Chronic Schizophrenic Patients

1990 • 275 citations

Effects of clozapine on cognitive function in schizophrenia.

1994 • 200 citations

The effects of neuroleptics on neuropsychological test results of schizophrenics

1988 • 200 citations

The relationship of social cognition to ward behavior in chronic schizophrenia

1996 • 197 citations

Spatial working memory deficits and their relationship to negative symptoms in unmedicated schizophrenia patients

1996 • 183 citations

Neuropsychological change in patients with schizophrenia after treatment with quetiapine or haloperidol.

2001 • 182 citations

Cognitive dysfunction in schizophrenia: comparison of treatment with atypical antipsychotic agents and conventional neuroleptic drugs

1996 • 172 citations

Relations of Symptoms to Cognitive Deficits in Schizophrenia

1993 • 166 citations

Interpersonal Problem Solving and Information Processing in Schizophrenia

1995 • 151 citations

Effects of dopamine depletion from the caudate-putamen and nucleus accumbens septi on the acquisition and performance of a conditional discrimination task

1990 • 137 citations

The psychopathology, neuropsychology, and neurobiology of associative and working memory in schizophrenia

1993 • 126 citations

Risperidone, negative symptoms and cognitive deficit in schizophrenia: an open study

1997 • 122 citations

Effects of neuroleptic medications on the cognition of patients with schizophrenia: a review of recent studies.

1996 • 121 citations

Improvement of Cognitive Function in Schizophrenic Patients Receiving Clozapine or Zotepine: Results from a Double-Blind Study

1997 • 108 citations

Relationships between changes in symptom ratings, neuropsychological test performance and quality of life in schizophrenic patients treated with clozapine

1997 • 104 citations

Affect Recognition in Schizophrenia: A Synthesis of Findings across Three Studies

1997 • 104 citations

Risperidone vs. haloperidol on reaction time, manual dexterity, and motor learning in treatment-resistant schizophrenia patients

1998 • 89 citations

The Effect of Risperidone on Cognition in Patients with Schizophrenia

1996 • 86 citations

The effects of neuroleptics on neuropsychological test results of schizophrenics

1988 • 69 citations

Cognition and Social Functioning in Schizophrenia

1997 • 66 citations

Cognitive dysfunction in schizophrenia and its importance to outcome: the place of atypical antipsychotics in treatment.

1999 • 66 citations

Practice-related improvement in information processing with novel antipsychotic treatment

2000 • 64 citations

The Effect of Risperidone on Cognition in Patients with Schizophrenia

1996 • 63 citations

Long-term impact of clozapine and psychosocial treatment on psychiatric symptoms and cognitive functioning

1996 • 62 citations

Cognitive impairment as a target for pharmacological treatment in schizophrenia

1995 • 60 citations

Effects of clozapine, fluphenazine, and placebo on reaction time measures of attention and sensory dominance in schizophrenia

1994 • 58 citations

Deficient motor synchrony in schizophrenic disorders: Clinical correlates

1985 • 51 citations

Generalization effects of training on the Wisconsin card sorting test for schizophrenia patients

1996 • 51 citations

Full length article

1998 • 47 citations

Should schizophrenia be treated as a neurocognitive disorder?

1999 • 33 citations

Deficit of central executive component of working memory in schizophrenia

1996 • 19 citations

Neuropsychological change in early phase schizophrenia over twelve months of treatment with olanzapine, risperidone, or haloperidol

1998 • 17 citations

Cognitive Effects of Typical Antipsychotic Treatment: Another Look

2000 • 17 citations

Assessing cognitive function in schizophrenics and patients with Alzheimer's disease

1995 • 10 citations