Effect of continuous intrathecal infusion of ω-conopeptides, N-type calcium-channel blockers, on behavior and antinociception in the formalin and hot-plate tests in rats

Chronic catheterization of the spinal subarachnoid space

1976 • 2,244 citations

Classes of Calcium Channels in Vertebrate Cells

1989 • 1,082 citations

Omega-conotoxin: direct and persistent blockade of specific types of calcium channels in neurons but not muscle.

1987 • 767 citations

Peptide Neurotoxins from Fish-Hunting Cone Snails

1985 • 742 citations

Calcium Action in Synaptic Transmitter Release

1987 • 742 citations

Antinociceptive actions of spinal nonsteroidal anti-inflammatory agents on the formalin test in the rat.

1992 • 651 citations

Mu and delta receptors belong to a family of receptors that are coupled to potassium channels.

1987 • 616 citations

A new conus peptide ligand for mammalian presynaptic Ca2+ channels

1992 • 487 citations

Calcium Channels in Vertebrate Cells

1990 • 454 citations

Ca2+ channels in rat central and peripheral neurons: High-threshold current resistant to dihydropyridine blockers and ω-conotoxin

1991 • 423 citations

Release of substance P from the cat spinal cord.

1987 • 371 citations

Neuronal calcium channel antagonists. Discrimination between calcium channel subtypes using .omega.-conotoxin from Conus magus venom

1987 • 337 citations

Voltage-sensitive calcium channels in spinal nociceptive processing: blockade of N- and P-type channels inhibits formalin-induced nociception

1994 • 297 citations

Characterization of two kinds of high-voltage-activated Ca-channel currents in chick sensory neurons

1989 • 274 citations

Activation of μ opioid receptors inhibits transient high- and low-threshold Ca 2+ currents, but spares a sustained current

1991 • 202 citations

Characterization of the electrically evoked release of substance P from dorsal root ganglion neurons: methods and dihydropyridine sensitivity

1988 • 190 citations

Do calcium channel classifications account for neuronal calcium channel diversity?

1991 • 178 citations

Modulation of vertebrate neuronal calcium channels by transmitters

1991 • 175 citations

Conotoxins.

1991 • 150 citations

ω-Conotoxin-sensitive voltage-operated calcium channels in vertebrate cells

1991 • 126 citations

Potency of infused spinal antinociceptive agents is inversely related to magnitude of tolerance after continuous infusion.

1989 • 120 citations

Neurochemical evidence for the involvement of N-type calcium channels in transmitter secretion from peripheral endings of sensory nerves in guinea pigs

1990 • 111 citations

Apparent lack of tolerance in the formalin test suggests different mechanisms for morphine analgesia in different types of pain

1981 • 99 citations

Release of calcitonin gene-related peptide like-immunoreactivity induced by electrical field stimulation from rat spinal afferents is mediated by conotoxin-sensitive calcium channels

1992 • 84 citations

Neurobiological Mechanisms of Opioid Tolerance and Dependence

1991 • 84 citations

Pharmacological modulation of voltage-dependent calcium channels in intact cells

2006 • 78 citations

Sufentanil, Morphine, Met-enkephalin, and k-Agonist (U-50,488H) Inhibit Substance P Release from Primary Sensory Neurons

1989 • 69 citations

The spinal pharmacology of facilitation of afferent processing evoked by high-threshold afferent input of the postinjury pain state.

1993 • 67 citations

Properties of Calcium Channels Isolated with Spider Toxin, FTX

1991 • 58 citations

Magnitude of opioid dependence after continuous intrathecal infusion of μ- and δ-selective opioids in the rat

1989 • 26 citations