Evidence for chromatin structure as a regulatory determinant in HLA-DR ?gene expression

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Chromosomal Subunits in Active Genes Have an Altered Conformation

1976 • 1,842 citations

Cytoplasmic dot hybridization. Simple analysis of relative mRNA levels in multiple small cell or tissue samples.

1982 • 1,333 citations

Isolation and Characterization of Full-Length cDNA Clones for Human α-, β-, and γ-Actin mRNAs: Skeletal but Not Cytoplasmic Actins Have an Amino-Terminal Cysteine that Is Subsequently Removed

1983 • 1,220 citations

Continuous culture of human lymphoblasts from peripheral blood of a child with acute leukemia

1965 • 1,213 citations

The 5′ ends of Drosophila heat shock genes in chromatin are hypersensitive to DNase I

1980 • 1,114 citations

The class II molecules of the human and murine major histocompatibility complex

1984 • 664 citations

Genes regulating HLA class I antigen expression in T-B lymphoblast hybrids

1985 • 580 citations

Active chromatin

1982 • 549 citations

Isolation and characterization of full-length cDNA clones for human alpha-, beta-, and gamma-actin mRNAs: skeletal but not cytoplasmic actins have an amino-terminal cysteine that is subsequently removed.

1983 • 546 citations

Selective digestion of transcriptionally active ovalbumin genes from oviduct nuclei.

1976 • 523 citations

Chromatin structure and protein binding in the putative regulatory region of the c-myc gene in burkitt lymphoma

1984 • 443 citations

DNAase I-hypersensitive sites of chromatin

1981 • 410 citations

Activating protein factor binds in vitro to upstream control sequences in heat shock gene chromatin

1984 • 329 citations

Interaction of specific nuclear factors with the nuclease-hypersensitive region of the chicken adult β-globin gene: Nature of the binding domain

1985 • 255 citations

Specific factor conferring nuclease hypersensitivity at the 5' end of the chicken adult beta-globin gene.

1984 • 249 citations

Induction of altered chromatin structures by simian virus 40 enhancer and promoter elements

1984 • 217 citations

Homozygous deletions that simultaneously eliminate expressions of class I and class II antigens of EBV-transformed B-lymphoblastoid cells. I. Reduced proliferative responses of autologous and allogeneic T cells to mutant cells that have decreased expression of class II antigens

1984 • 187 citations

Organization of human δ- and β-globin genes in cellular DNA and the presence of intragenic inserts

1978 • 141 citations

Chromatin changes accompany immunoglobulin κ gene activation: a potential control region within the gene

1982 • 138 citations

Structure and nucleotide sequence of the heavy chain gene of HLA-DR.

1983 • 132 citations

Tissue-specific exposure of chromatin structure at the 5' terminus of the rat preproinsulin II gene.

1981 • 129 citations

A complex of interacting DNAase I-hypersensitive sites near the drosophila glue protein gene, Sgs4

1982 • 126 citations

B-Lymphoid cell lines derived fromHLA-D homozygous donors

1979 • 68 citations

Isolation of a cDNA clone for the human HLA-DR antigen alpha chain by using a synthetic oligonucleotide as a hybridization probe.

1982 • 63 citations

Human Ir Genes: Structure and Function

1983 • 40 citations

Formal discussion: the role of transplantation in the experimental investigation of human leukemia and lymphoma.

1967 • 38 citations

Human T-B lymphoblast hybrids express HLA-DR specificities not expressed by either parent

1982 • 19 citations

Evidence for methylation as a regulatory mechanism in HLA-DR x gene expression

1985 • 17 citations

Expression of T-lymphoblast-encoded HLA-DR antigens on human T-B lymphoblast hybrids

1983 • 12 citations

Isolation and Characterization of a Human Pro α2(I) Collagen Gene Segment

1984 • 12 citations

Analysis of Globin Gene Structure in Patients with β Thalassemia by Restriction Endonuclease Mapping

1981 • 5 citations