Partial characterization of solubilized platelet imipramine binding sites using a new probe, [3H]3-cyanoimipramine ([3H]Ro 11-2465)

A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples

1978 • 6,494 citations

Reduced uptake of serotonin but unchanged 3H-imipramine binding in the platelets from cirrhotic patients

1981 • 106 citations

Solubilization of the platelet plasma membrane serotonin transporter in an active form.

1980 • 97 citations

Molecular aspects of the imipramine ‘receptor’

1984 • 40 citations

Binding of [3H]Ro 11-2465. Possible identification of a subclass of [3H]imipramine binding sites.

1983 • 36 citations

Temperature dependence of the binding of [3H]mepyramine and related compounds to the histamine H1 receptor.

1983 • 33 citations

Solubilization of imipramine-binding protein from human blood platelets

1983 • 22 citations

Solubilization and assay of [3H]imipramine binding sites from human platelets

1983 • 20 citations

Specific binding sites in rat brain for a new and potent inhibitor of 5-hydroxytryptamine uptake: Ro 11-2465

1980 • 19 citations

Temperature-sensitive reversible loss of [3H]imipramine binding sites: Evidence suggesting different conformational states

1983 • 18 citations

Alterations in temperature and histamine receptor function.

1977 • 13 citations

Temperature-sensitive conformational changes in membrane-bound and solubilized [3H]imipramine binding sites

1983 • 11 citations

Alterations in temperature and histamine receptor function.

1977 • 8 citations

Effects of Ro 11-2465, a new psychotropic agent on the uptake of serotonin by human platelets--in vitro determination of the IC50.

1981 • 7 citations

The effect of multiple rising doses of Ro 11-2465 (serotonin uptake inhibitor) on serotonin content of human platelets

1981 • 6 citations