A predicted consensus structure for the protein kinase C2 homology (C2H) domain, the repeating unit of synaptotagmin

The relation between the divergence of sequence and structure in proteins.

1986 • 2,373 citations

Structural design and molecular evolution of a cytokine receptor superfamily.

1990 • 2,104 citations

A novel arachidonic acid-selective cytosolic PLA2 contains a Ca2+-dependent translocation domain with homology to PKC and GAP

1991 • 1,709 citations

Exhaustive Matching of the Entire Protein Sequence Database

1992 • 844 citations

Phospholipid binding by a synaptic vesicle protein homologous to the regulatory region of protein kinase C

1990 • 829 citations

Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate

1994 • 749 citations

The structure, expression, and properties of additional members of the protein kinase C family.

1988 • 706 citations

Structure of the first C2 domain of synaptotagmin I: A novel Ca2+/phospholipid-binding fold

1995 • 680 citations

Sequence similarity of phospholipase C with the non-catalytic region of src

1988 • 541 citations

The PH domain: a common piece in the structural pathcwork of signalling proteins

1993 • 536 citations

The SWISS-PROT protein sequence data bank

1992 • 530 citations

A novel phorbol ester receptor/protein kinase, nPKC, distantly related to the protein kinase C family

1988 • 414 citations

Redefining the goals of protein secondary structure prediction

1994 • 341 citations

SH3 — an abundant protein domain in search of a function

1992 • 280 citations

Structure of the pleckstrin homology domain from β-spectrin

1994 • 233 citations

Solution structure of a pleckstrin-homology domain

1994 • 211 citations

Patterns of divergence in homologous proteins as indicators of secondary and tertiary structure: A prediction of the structure of the catalytic domain of protein kinases

1991 • 173 citations

Similarity of three-dimensional structure between the immunoglobulin domain and the copper, zinc superoxide dismutase subunit

1976 • 162 citations

Interaction of the p85 subunit of PI 3-kinase and its N-terminal SH2 domain with a PDGF receptor phosphorylation site: structural features and analysis of conformational changes.

1992 • 132 citations

Conservation analysis and structure prediction of the SH2 family of phosphotyrosine binding domains

1992 • 107 citations

Crystal structure of liganded and unliganded forms of bovine plasma retinol-binding protein

1993 • 83 citations

The Limits of Protein Secondary Structure Prediction Accuracy from Multiple Sequence Alignment

1993 • 77 citations

An algorithm to generate low-resolution protein tertiary structures from knowledge of secondary structure.

1994 • 73 citations

The crystal structure of pseudoazurin from Alcaligenes faecalis S‐6 determined at 2.9 Å resolution

1987 • 62 citations

Topological and stereochemical restrictions in β-sandwich protein structures

1993 • 55 citations

Tertiary Structure Prediction

1989 • 54 citations

Bona Fide Prediction of Aspects of Protein Conformation

1994 • 53 citations

Physical-chemical studies on the role of the metal ions in concanavalin A

1976 • 51 citations

Interaction of protein kinase C isozymes with phosphatidylinositol 4,5-bisphosphate

1991 • 47 citations

Computational biochemistry research at ETH

1991 • 28 citations

Microbial Energy Transduction: Genetics, Structure, and Function of Membrane Proteins

1986 • 25 citations

A Secondary Structure Prediction of the Hemorrhagic Metalloprotease Family

1993 • 23 citations

Evolution and Structural Theory: The Frontier Between Chemistry and Biology

1990 • 23 citations

Evaluating Predictions of Secondary Structure in Proteins

1994 • 19 citations

A prediction of the secondary structure of the pleckstrin homology domain

1994 • 13 citations