Bronchoprotective role for endogenous prostaglandin E2

IgE production by normal human lymphocytes is induced by interleukin 4 and suppressed by interferons gamma and alpha and prostaglandin E2.

1988 • 939 citations

Relationship of inhibition of prostaglandin biosynthesis by analgesics to asthma attacks in aspirin-sensitive patients.

1975 • 490 citations

Effects of Prostaglandins on Human Bronchial Muscle

1968 • 240 citations

Effect of Inhaled Prostaglandin E₂on Allergen-induced Asthma

1993 • 203 citations

Cyclooxygenase Metabolism of Endogenous Arachidonic Acid by Cultured Human Tracheal Epithelial Cells

1989 • 202 citations

Effect of inhaled PGE2 on exercise-induced bronchoconstriction in asthmatic subjects.

1994 • 152 citations

The effect of indomethacin on exercise-induced bronchoconstriction and refractoriness after exercise.

1986 • 119 citations

Specific receptors for prostaglandins in airways

1980 • 115 citations

Effect of prostaglandins F2 alpha and E2 on airway conductance in healthy subjects and asthmatic patients.

1975 • 111 citations

Mediator and cytokine mechanisms in asthma.

1993 • 106 citations

Analysis of prostaglandin E2 effect on T lymphocyte activation. Abrogation of prostaglandin E2 inhibitory effect by the tumor promotor 12.0 tetradecanoyl phorbol-13 acetate.

1987 • 92 citations

Actions of indomethacin and prostaglandins on neuroeffector transmission in the dog trachea

1981 • 90 citations

Effect of inhaled prostaglandin E2 on bronchial reactivity to sodium metabisulphite and methacholine in patients with asthma.

1991 • 78 citations

Production of PGE₂ by bovine cultured airway smooth muscle cells and its inhibition by cyclo‐oxygenase inhibitors

1994 • 75 citations

A Comparison of the Refractory Periods Induced by Hypertonic Airway Challenge and Exercise in Bronchial Asthma^1,2

1987 • 64 citations

Inhaled frusemide and exercise induced asthma: evidence of a role for inhibitory prostanoids.

1992 • 61 citations

Aspects of Bronchial Reactivity to Prostaglandins and Aspirin in Asthmatic Patients

1977 • 55 citations

Cyclooxygenase metabolites are compartmentalized in the human lower respiratory tract

1987 • 47 citations

Selective Inhibition of the Cutaneous Late but Not Immediate Allergic Response to Antigens by Misoprostol, a PGE Analog: Results of a Double-blind, Placebo-controlled Randomized Study

1993 • 44 citations

Clinical, functional and pathogenetic aspects of bronchial reactivity to prostaglandins F2alpha, E1, and E2.

1976 • 41 citations

Pre-junctional inhibitory action of prostaglandin E2 on excitatory neuro-effector transmission in the human bronchus

1990 • 37 citations

The effect of indomethacin on the refractory period occurring after the inhalation of ultrasonically nebulized distilled water

1987 • 36 citations

Inhibition of sodium metabisulphite induced bronchoconstriction by frusemide in asthma: role of cyclooxygenase products.

1994 • 25 citations

Analysis of Prostaglandin E2 Effect on T Lymphocyte Activation

1987 • 23 citations

Repeated Methacholine Challenge Produces Tolerance in Normal but Not in Asthmatic Subjects

1992 • 22 citations

Calcium-dependent stimulation of renal medullary prostaglandin synthesis by furosemide.

1982 • 20 citations

Effect of loop diuretics on cholinergic neurotransmission in human airways in vitro.

1994 • 18 citations

Refractoriness to inhaled sodium metabisulphite in subjects with mild asthma

1994 • 16 citations

Cross refractoriness between sodium metabisulphite and exercise induced asthma.

1994 • 16 citations

Inhaled frusemide and asthma

1990 • 14 citations

PRODUCTION OF PGE(2) BY CULTURED AIRWAY SMOOTH-MUSCLE CELLS AND ITS INHIBITION BY PROSTAGLANDIN SYNTHETASE INHIBITORS

1993 • 6 citations